Clinical Trials Sponsored by 2seventy bio

Total 2450 results

Takara Bio Inc.

Completed

A Study of TBI-1401(HF10) in Patients With Solid Tumors With Superficial Lesions

Solid Tumor

Japan
AB2 Bio Ltd.

Completed

Therapeutic Use of Tadekinig Alfa in Adult-onset Still's Disease

Still's Disease, Adult-Onset

Germany, France, Switzerland
Sesen Bio, Inc.

Terminated

Study of Proxinium for Treating Patients With Squamous Cell Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms | Carcinoma, Squamous Cell | Squamous Cell Carcinoma of the Head and Neck | Neoplasms, Squamous Cell | Mouth Neoplasms

United States, Canada
Entera Bio Ltd.

Completed

A Three Stage, Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of Oral PTH (1-34) in Healthy Subjects

Drug Safety

Israel
PT Bio Farma

Completed

Antibody Persistence, Immune Response and Safety After Doses of Pentabio Vaccine

Healthy

Indonesia
PT Bio Farma

Completed

Evaluation on Immunogenicity and Safety Profile of Trivalent OPV (tOPV Bio Farma)

Healthy

Indonesia
PT Bio Farma

Completed

Safety of Hib Vaccine (Bio Farma)

Healthy

Indonesia
Bio Products Laboratory

Completed

Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.

Primary Immunodeficiency | Wiskott-Aldrich Syndrome | Hypogammaglobulinemia | Common Variable Hypogammaglobulinemia | X-linked Hypogammaglobulinemia | Immunodeficiency With Hyper-IgM

United States
Lotus Bio Inc.

Unknown

Efficacy Evaluation of a Novel Diagnostic Assay Which is the Basis for Seaforia Diagnostic System

Male Fertility

Israel
Ora Bio Ltd.

Unknown

Pilot Study to Evaluate the Safety and Efficacy of Treatment With ORA102 Combined With Avastin (Bevacizumab) Versus Avastin Alone, in Patients With Neovascular Age Related Macular Degeneration (AMD)

Macular Degeneration

Israel
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Statin

Dyslipidemia

Sweden
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe

Hypercholesterolemia

Sweden
Karo Bio AB

Completed

Eprotirome for the Treatment of Dyslipidemia, Efficacy and Safety 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia

Primary Hypercholesterolemia

Sweden
Viela Bio

Withdrawn

Safety and Tolerability of Inebilizumab, VIB4920, or the Combination in Highly Sensitized Candidates Awaiting Kidney Transplantation From a Deceased Donor

Highly Sensitized Patients on Waiting List for Kidney Transplantation

United States
Viela Bio

Terminated

Treatment and Prevention of Acute Lung Injury (ALI) in Patients With COVID-19 Infection (ALI)

Acute Lung Injury

United States
Viela Bio

Completed

A Phase 1b Study of MEDI4920 in Participants With Adult-onset Rheumatoid Arthritis

Adult Onset Rheumatoid Arthritis

United States, Poland
Opna Bio LLC

Not yet recruiting

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Bio-Thera Solutions

Recruiting

A Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of the Combination of BAT8008 With BAT1308 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
International Bio service

Not yet recruiting

Bioequivalence Study of Generic Celecoxib 200 mg Capsules

Healthy Volunteer
International Bio service

Not yet recruiting

Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
International Bio service

Not yet recruiting

Bioequivalence Study of Diacerein 50 mg Capsule in Healthy Thai Volunteers

Healthy Volunteer
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

Severe Asthma

United States, United Kingdom, Canada
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps (VIBRANT)

Chronic Rhinosinusitis With Nasal Polyps

United States
Bio-Thera Solutions

Not yet recruiting

BAT1308 Combined With Platinum-Based Chemotherapy± Bevacizumab For PDL1-Positive (CPS ≥1) Cervical Cancer

Cervical Cancer

China
Inmune Bio, Inc.

Recruiting

Study of INKmune in Patients With mCRPC (CaRe Prostate) (CaRe)

Cancer | Metastatic Castration-resistant Prostate Cancer | mCRPC

United States
Bio-Thera Solutions

Recruiting

A Clinical Trial of BAT4406F Injection in Patients With Neuromyelitis Optica Spectrum Disorders

Optic Neuromyelitis Spectrum Disease

China
Solarea Bio, Inc

Recruiting

SBD121, a Synbiotic Medical Food for RA Management

Rheumatoid Arthritis

Australia, New Zealand
Entera Bio Ltd.

Recruiting

Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo

Hypoparathyroidism

Israel
Bio-Thera Solutions

Recruiting

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

Advanced or Metastatic Solid Tumors

China
Cellf Bio LLC

Recruiting

Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence

Fecal Incontinence

United States
Cellevolve Bio Inc

Not yet recruiting

A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML (ASCEND-JC)

Progressive Multifocal Leukoencephalopathy
RedCloud Bio
Parexel

Recruiting

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

Non-small Cell Lung Cancer

United States
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States
Bio-Thera Solutions

Recruiting

Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8006 for Injection

Advanced Solid Tumors

China
Inmune Bio, Inc.

Recruiting

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation (MINDFuL)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment

Australia, Canada, United Kingdom, Poland, Germany
Bio-Thera Solutions

Recruiting

Assessment of Safety , Clinical Efficacy With QLETLI in Non-infectious Uveitis (UV)

Uveitis

China
Bio-Thera Solutions

Recruiting

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors

Advanced Solid Tumor

China
Bio-Thera Solutions

Recruiting

Assessment of Safety and Preliminary Clinical Efficacy With BAT6005 in Advanced Malignant Solid Tumors

Locally Advanced or Metastatic Solid Tumors

China
ABL Bio, Inc.

Recruiting

This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects With Any Progressive Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumor

Korea, Republic of, United States
Adicet Bio, Inc

Recruiting

A Phase 1 Study of ADI-001 in B Cell Malignancies (GLEAN-1)

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma

United States
GID BIO, Inc.

Not yet recruiting

Adipose-derived SVF for Treatment of Erectile Dysfunction (ED)

Erectile Dysfunction

United States
Bio-Thera Solutions

Active, not recruiting

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration

Neovascular (Wet) Age-related Macular Degeneration

China
Solarea Bio, Inc

Active, not recruiting

Food Trial Evaluating the Efficacy of SBD111 Versus Placebo for the Clinical Dietary Management of the Metabolic Processes of Osteopenia

Osteopenia

Australia
Gasherbrum Bio, Inc

Completed

Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

Overweight or Obesity | Type2 Diabetes Mellitus

United States
Avenge Bio, Inc

Terminated

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer | Primary Peritoneal Carcinoma | Neoplasm, Ovarian | Adenocarcinoma Ovary | Serous Adenocarcinoma of Ovary | Serous Adenocarcinoma of Primary Peritoneum | High Grade Serous Adenocarcinoma

United States
Bio-Thera Solutions

Completed

Clinical Study of the Safety and Efficacy of BAT5906 Injection

Diabetic Macular Edema

China
Bio-Thera Solutions

Completed

Comparative Study to Evaluate the Pharmacokinetics of BAT2506 vs Simponi® in Healthy Subjects

Psoriatic Arthritis

China
Bio-Thera Solutions

Active, not recruiting

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumor Patients in China

Advanced Solid Tumors

China
Gritstone bio, Inc.

Completed

Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)

COVID-19 | SARS-CoV-2

South Africa
Passage Bio, Inc.

Suspended

Study of Safety, Tolerability and Efficacy of PBKR03 in Pediatric Subjects With Early Infantile Krabbe Disease (GALax-C)

Leukodystrophy, Globoid Cell

United States, Brazil, Netherlands, United Kingdom, Canada, Israel

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