Clinical Trials Sponsored by Bionorica SE

Total 253 results

Biotronik SE & Co. KG

Completed

Master Study for the Investigation of Safety and Efficacy of the SIELLO Pacemaker Leads

Cardiac Pacemaker Syndrome

Germany
Biotronik SE & Co. KG

Completed

ProMRI 3T ENHANCED Master Study

Safety of MR (Magnetic Resonance)-Conditional ICDs

Australia, Germany, Switzerland, Austria, Singapore
Biotronik SE & Co. KG

Terminated

European Health Economic Trial on Home Monitoring in ICD and CRT-D Patients (EuroEco) (EuroEco)

Ventricular Fibrillation | Tachycardia, Ventricular | Ventricular Flutter

Spain, Germany, Finland, Belgium, Netherlands, United Kingdom
Biotronik SE & Co. KG

Terminated

Clinical effecT of Heart Failure Management Via Home Monitoring With a Focus on Atrial Fibrillation (effecT) (effecT)

Atrial Fibrillation | Heart Failure (HF)

France, Czech Republic, Germany, Netherlands, Belgium, Sweden, United Kingdom
Biotronik SE & Co. KG

Completed

Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators. (THORN)

Atrial Fibrillation | Ventricular Fibrillation | Ventricular Tachycardia | Sudden Cardiac Death | ICD

France
Biotronik SE & Co. KG

Completed

DF4 Master Study (Safety and Efficacy Study)

Heart Failure | Ventricular Fibrillation | Ventricular Tachycardia | Sudden Cardiac Death

Germany
Biotronik SE & Co. KG

Completed

Assessment of Intracardiac Electrograms Transmitted by Home Monitoring for the Remote Follow-up of Pacemaker (PREMS) (PREMS)

Bradycardia

France
Biotronik SE & Co. KG

Completed

Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study (VIPERS)

Sick Sinus Syndrome

Italy
Biotronik SE & Co. KG

Completed

Iperia/Sentus QP Study

Heart Failure | Tachyarrhythmia

Spain, Netherlands, Denmark, Germany, Switzerland, Finland, Latvia, Italy, Singapore, Austria, United Kingdom
Biotronik SE & Co. KG

Completed

NORDIC ICD (Cardioverter Defibrillator Implantation) Trial

Ventricular Tachyarrhythmia

Germany, Sweden
Biotronik SE & Co. KG

Completed

Survival of Patients With Primary Prophylactic ICD Indication (SPIRIT-ICD)

Tachycardia, Ventricular | Primary Prevention | Sudden Cardiac Death

Israel, Germany, Hungary, Switzerland, Austria, Czech Republic, Latvia, New Zealand, Poland, Slovakia, Spain
Biotronik SE & Co. KG

Completed

BioMonitor Master Study (BioMonitor)

ATRIAL FIBRILLATION, Syncope

Germany
Biotronik SE & Co. KG

Completed

Evia/Entovis HF-T Master Study

Indication for Cardiac Resynchronization Therapy (CRT)

Hungary
Biotronik SE & Co. KG

Completed

Fast VT Episodes Are Terminated by ATP One Shot (FavoriteATP)

Ventricular Tachycardia, Monomorphic

Austria, Finland, Germany, Israel
Biotronik SE & Co. KG

Completed

Lumax 740 Master Study (Lumax 740)

Safety and Efficacy of the Lumax 740 ICD Family

Germany
Biotronik SE & Co. KG

Completed

Linox Smart S DX PME/Master Study

ICD Indication

Germany
Biotronik SE & Co. KG

Completed

Remote Follow-up of Patients Receiving Implantable Cardioverter Defibrillator for Prophylactic Therapy (REFORM)

Ventricular Fibrillation | Ventricular Tachycardia

Germany, Czech Republic
Biotronik SE & Co. KG

Completed

Isthmus Ablation With Gold Electrode for Treatment of Atrial Flutter (AURUM 8)

Atrial Flutter

Germany, Czech Republic, Hungary
Biotronik SE & Co. KG

Completed

Study to Verify Proper Detection of Supraventricular Tachyarrhythmia With Single-Lead Dual-Chamber Implantable Cardioverter-Defibrillators (ADRIA)

Tachyarrhythmia

Germany, Switzerland
BioNTech US Inc.

Recruiting

NEO-PTC-01 in Patients With Advanced or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

Belgium, Netherlands, Spain
Olympus Europe SE & Co. KG

Completed

A Clinical Study With the Medical Device PowerSpiral for Deep Enteroscopy (SAMISEN)

Small Bowel Disease

Finland, Germany, Belgium, Denmark, France, Norway
BioNTech SE
Seventh Framework Programme

Completed

RNA-Immunotherapy of IVAC_W_bre1_uID and IVAC_M_uID (TNBC-MERIT)

Breast Cancer (Triple Negative Breast Cancer (TNBC))

Sweden, Germany
Olympus Europe SE & Co. KG

Recruiting

A Clinical Study on Endoscopic and Histopathological Outcomes of Screening and Surveillance Colonoscopies (CODACO)

Colonic Polyp

Spain, Germany, Sweden
University of Southampton
BioNTech SE

Completed

HARE-40: HPV Anti-CD40 RNA vaccinE (HARE-40)

Unknown Primary Tumors | Head and Neck Neoplasm | Cervical Neoplasm | Penile Neoplasms Malignant | Human Papilloma Virus Related Carcinoma

United Kingdom
Olympus Europe SE & Co. KG

Terminated

A Clinical Study With the Medical Device PowerSpiral for Endoscopic Retrograde Cholangio-Pancreatography (ERCP) (SAMISEN-B)

Cholangiopancreatography, Endoscopic Retrograde

Belgium, Germany, Norway
Hoosier Cancer Research Network
Bionomics Limited

Completed

BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma

Renal Cell Carcinoma

United States, Australia, Singapore
BioNTech Research & Development, Inc.

Recruiting

Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies

Pancreatic Cancer

United States
Biotronik SE & Co. KG
Biotronik, Inc.

Terminated

Sentus QP - Extended CRT Evaluation With Quadripolar Left Ventricular Leads (QP ExCELs)

Heart Failure

United States, Switzerland, Denmark, Israel, Hungary, Italy, Germany, Austria, Australia, Slovakia, Spain
BioNTech RNA Pharmaceuticals GmbH

Completed

RBL001/RBL002 Phase I Clinical Trial (MERIT)

Melanoma

Austria, Germany
Biotronik France
Biotronik SE & Co. KG

Completed

Observational Study of Patient Comprehension, Perception, Fears and Appreciation Following Home-Monitoring Implementation (Educ@t)

Tachycardia | Defibrillators

France
University Medical Center Groningen
BioNTech SE

Terminated

Ovarian Cancer Treatment With a Liposome Formulated mRNA Vaccine in Combination With (Neo-)Adjuvant Chemotherapy (OLIVIA)

Ovarian Cancer

Netherlands
Se-Hoon Lee

Unknown

Genomic Analysis to Identify a Predictive Biomarker for Immunotherapy (LC_Biomarker)

Lung Cancer

Korea, Republic of
BioNTech RNA Pharmaceuticals GmbH

Completed

IVAC MUTANOME Phase I Clinical Trial

Melanoma

Austria, Germany
Biotronik France
Biotronik SE & Co. KG

Completed

Strategy of Early Detection and Active Management of Supraventricular Arrhythmia With Telecardiology (SETAM) (SETAM)

Atrial Fibrillation | Atrial Flutter | Atrial Tachycardia

France
Olympus Europe SE & Co. KG
Cromsource

Recruiting

Safety and Efficacy of the Olympus CADe System in Real-time Colonoscopy (EuroCADe)

Colorectal Cancer

Germany, Spain, Belgium, Sweden
BioNTech Research & Development, Inc.

Terminated

Study of 177Lu Human Monoclonal Antibody 5B1 (MVT-1075) in Combination With a Blocking Dose of MVT-5873 as Radioimmunotherapy

Pancreatic Carcinoma | Tumors That Express CA 19-9

United States
Se-Hoon Lee

Terminated

AZD2811 and Durvalumab (MEDI4736) Combination Therapy in Relapsed Small Cell Lung Cancer (SUKSES-N5)

SCLC, Recurrent

Korea, Republic of
Biotronik France
Biotronik SE & Co. KG

Completed

Evaluate the Benefits of Pacemaker Follow-Up With Home-Monitoring (COMPAS)

Bradycardia | Pacemaker, Artificial

France
University of Chicago
Biotronik SE & Co. KG

Recruiting

Conduction System Pacing International Registry (CONSPIRE)

Heart Failure | Bradyarrhythmia

United States, Netherlands, Sweden, Spain
Memorial Sloan Kettering Cancer Center
BioNTech SE

Active, not recruiting

Study of a New Technique for Imaging Pancreatic Cancer

Pancreatic Cancer | Tumors That Express CA19-9

United States
Se-cure Pharmaceuticals Ltd.
Clalit Health Services

Unknown

A Double-Blind Study to Evaluate the Effect of Femarelle® on Menopausal on Vasomotor Symptoms

Hot Flashes | Menopause

Israel
Se Jun Park

Recruiting

Dabrafenib Plus Trametinib in Patients With Advanced Solid Tumor Having BRAF V600E Mutation or Clinically Actionable BRAF Gene Alterations

Cancer

Korea, Republic of
Se-cure Pharmaceuticals Ltd.
Clalit Health Services

Recruiting

The Effect of BRIZO on Lower Urinary Tract Symptoms (LUTS) Related to Benign Prostatic Hypertrophy (BPH)

BPH Without Urinary Obstruction and Other Lower Urinary Tract Symptoms (LUTS)

Israel
BioNTech Cell & Gene Therapies GmbH

Recruiting

A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors

Solid Tumor

Australia, Germany, Netherlands, Sweden
Erasmus Medical Center
Biotronik SE & Co. KG

Active, not recruiting

Direct Complete Versus Staged Complete Revascularization in Patients Presenting With Acute Coronary Syndromes and Multivessel Disease (BioVasc)

Acute Coronary Syndrome

Netherlands
BioNTech US Inc.
Apexigen, Inc.

Terminated

A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma

Metastatic Melanoma

United States
Biotronik SE & Co. KG
University Hospital Heidelberg

Terminated

Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study

Paroxysmal Atrial Fibrillation

Germany, Netherlands, Switzerland, Hungary, Czechia
R&D Cardiologie
Biotronik SE & Co. KG

Unknown

Hybrid Sirolimus-eluting Versus Everolimus-eluting Stents for Total Coronary Occlusions (PRISON-IV)

Coronary Artery Disease | Coronary Disease | Coronary Stenosis

Netherlands, Belgium
Bionomics Limited
CPR Pharma Services Pty Ltd, Australia

Terminated

A Phase I, Dose Escalation Study of BNC101 in Patients With Metastatic Colorectal Cancer.

Colorectal Cancer

Australia
Biotronik SE & Co. KG
Biotronik Japan, Inc.

Recruiting

To Evaluate the Delivery Timing Safety and Efficacy of AntiTachycardia Pacing (BIO|ATP) (BIO|ATP)

Implantable Cardioverter Defibrillator(ICD)

Japan

Clinical Trials Sponsored by Bionorica SE

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