Clinical Trials Sponsored by Central Manchester University Hospitals NHS Foundation Trust

Total 1681 results

The Christie NHS Foundation Trust
University of Manchester

Withdrawn

A Proof of Concept, Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer (IMpALA)

Breast Cancer
University of Manchester
The Christie NHS Foundation Trust

Recruiting

Precision Medicine for Stem Cell Transplantation (PM-SCT)

Haematopoietic Stem Cell Transplantation

United Kingdom
University of Manchester
The Christie NHS Foundation Trust

Recruiting

Biomarkers for Clinical Hypoxia Evaluation in Cervical Cancer (Bio-CHECC)

Cervical Cancer

United Kingdom
Ironwood Pharmaceuticals, Inc.
Manchester University NHS Foundation Trust

Terminated

A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)

Irritable Bowel Syndrome Characterized by Constipation

United Kingdom
The Christie NHS Foundation Trust
University of Manchester

Terminated

The Goals of Care Initiative (GOCI)

Chemotherapy Effect | Decision-Making Oncology

United Kingdom
Manchester University NHS Foundation Trust
Rapid Rhythm Ltd

Completed

Wireless Handheld 8-lead ECG Device Performance in Heart Patients (Rapid Rhythm)

Atrial Fibrillation | Heart Murmurs

United Kingdom
Michelson Diagnostics Ltd.
Manchester University NHS Foundation Trust

Completed

Longitudinal Study of Chronic Wounds Using Novel Wound Measurement Technologies

Diabetic Foot Ulcer

United Kingdom
Lancashire Care NHS Foundation Trust
University of Manchester

Completed

Exploratory Trial of a Group Psychological Intervention for Postnatal Depression in British Mother's of South Asian Origin (ROSHNI-D)

Depression, Postpartum | Postnatal Depression in British South Asian Women

United Kingdom
Royal Victoria Infirmary
Manchester University NHS Foundation Trust

Unknown

Does CBT Improve the Perception/Impact of Cough and Breathlessness in IPF Patients

Cough | Idiopathic Pulmonary Fibrosis | Breathlessness

United Kingdom
Manchester University NHS Foundation Trust
Manchester Metropolitan University; University of Manchester; University of Birmingham

Completed

Transcapillary Plasma Refill in Advanced Chronic Kidney Disease (PRUf)

Haemodynamic Instability

United Kingdom
The Christie NHS Foundation Trust
University of Manchester

Not yet recruiting

Molecular Characterisation of Colorectal Cancer Peritoneal Metastases (COLOMET II)

Colorectal Cancer Metastatic
The Christie NHS Foundation Trust
University of Manchester

Not yet recruiting

Molecular Characterisation of Appendiceal Cancer

Appendiceal Cancer
University of Manchester
The Christie NHS Foundation Trust

Recruiting

Investigating the Tumour Immune Response of Radiotherapy (TIMM-RAD)

Cancer

United Kingdom
The Christie NHS Foundation Trust
University of Manchester

Recruiting

NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

Renal Cell Carcinoma | Cancer | Metastatic Melanoma | Non-small Cell Lung Cancer

United Kingdom
University of Manchester
The Christie NHS Foundation Trust

Recruiting

MR-BIO: A Study to Evaluate Changes in MR Imaging and Biological Parameters (MR-BIO)

Cancer

United Kingdom
The Christie NHS Foundation Trust
University of Manchester

Recruiting

Serial Tumour Biopsies and Blood Biomarkers in Melanoma

Melanoma

United Kingdom
The Christie NHS Foundation Trust
University of Manchester

Enrolling by invitation

Lung Screening in People Cured of Hodgkin Lymphoma

Hodgkin Lymphoma | Lung Cancer

United Kingdom
University of Manchester
The Christie NHS Foundation Trust

Completed

An Evaluation of the Psychological Impact of Early Phase Clinical Trials in Cancer Patients. (EPIC)

Depression | Cancer | Anxiety | Psychological Distress | Hope

United Kingdom
University of Manchester
The Christie NHS Foundation Trust

Unknown

Optimisation of Radiotherapy in Rectal Cancer (ORREC) (ORREC)

Rectal Adenocarcinoma

United Kingdom
Liverpool Women's NHS Foundation Trust
Manchester Metropolitan University

Completed

Use of Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) in Maintaining OAB Symptoms Improvement.

Overactive Bladder

United Kingdom
University of Manchester
Lancashire Care NHS Foundation Trust

Completed

Self Directed Positive Parenting Program (Triple P) for Psychosis: A Clinical Case Series

Schizophrenia | Spectrum | Disorders

United Kingdom
University of Edinburgh
Wellcome Trust; NHS Lothian; Manchester University NHS Foundation Trust; Oxford... and other collaborators

Completed

Prediction of Recurrent Events With 18F-Fluoride (PREFFIR)

Myocardial Infarction | Coronary Artery Disease

United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; Hull University Teaching Hospitals... and other collaborators

Completed

Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study (SPiRE)

Stillbirth

United Kingdom
Manchester University NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; Norfolk and Norwich University... and other collaborators

Completed

Flash-glucose Monitoring in Sub-optimally Controlled Type 1 Diabetes (FLASH-UK) (FLASH-UK)

Diabetes Mellitus, Type 1

United Kingdom
University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
University of Manchester
King's College London; Northern Care Alliance NHS Foundation Trust; University... and other collaborators

Completed

The Benefit of Minocycline on Negative Symptoms in Schizophrenia: Extent and Mechanisms (BeneMin)

Schizophrenia and Disorders With Psychotic Features
Prof Corinne Faivre-Finn
The Leeds Teaching Hospitals NHS Trust; University of Leeds; Manchester University... and other collaborators

Recruiting

Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy (ACCOLADE)

Lung Cancer

United Kingdom
University of Cambridge
Norfolk and Norwich University Hospitals NHS Foundation Trust; Barts & The... and other collaborators

Recruiting

Closing the Loop in People With Type 1 Diabetes (CLEAR Phase 2)

Type 1 Diabetes

United Kingdom
University College, London
University Hospital Southampton NHS Foundation Trust; Bangor University; St George... and other collaborators

Recruiting

Cognitive Rehabilitation for People With Cognitive Covid19

Long Covid19

United Kingdom
Portsmouth Hospitals NHS Trust
Manchester Metropolitan University

Completed

Retrospective Observational Analysis of a Cohort With Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
University Hospital Southampton NHS Foundation...
South Central Ambulance Service NHS Foundation Trust

Completed

Do Patients Suffering a Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?

Cardiac Arrest

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Papworth Hospital NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Validation of UK Protocols to Exclude Brain Blood Flow During Normothermic Regional Perfusion (NRP)

Cerebral Blood Flow
Manchester University NHS Foundation Trust
Novo Nordisk A/S

Completed

Comparison of Day and Night Closed-loop With Faster-acting Insulin Aspart With Insulin Aspart (AP-MFT-01)

Diabetes Mellitus, Type 1

United Kingdom
University of Manchester
Northern Care Alliance NHS Foundation Trust

Completed

Neurostimulation for Dysphagia in Parkinson's Disease

Brain Diseases | Parkinson Disease | Dysphagia | Swallowing Disorder.Other Specified

United Kingdom
Manchester University NHS Foundation Trust
Topcon Corporation; Optos, PLC

Withdrawn

Sub-threshold Photocoagulation of Diabetic Macular Oedema (MEM)

Diabetic Macular Oedema

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospital Birmingham... and other collaborators

Completed

A Prospective UK Multicentre Study of Kidney Donors (EARNEST)

Living Kidney Donors

United Kingdom
The Christie NHS Foundation Trust
Manchester University NHS Foundation Trust; Aptus Clinical Ltd.; Zenzium Ltd.

Completed

COntinuous Signs Monitoring In Covid-19 Patients (COSMIC-19)

COVID-19

United Kingdom
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
Vernalis (R&D) Ltd
Manchester University NHS Foundation Trust

Terminated

Phase II Open-Label Pilot Study of V3381 in Chronic Cough

Cough

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; University Hospital Birmingham NHS... and other collaborators

Withdrawn

Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF (RABLAP-AF)

Atrial Fibrillation

United Kingdom
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
University Hospital Southampton NHS Foundation...
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospitals, Leicester and other collaborators

Completed

CPET and Outcome After Oesophagogastric Cancer Surgery

Upper Gastrointestinal Disorders

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca; University of Manchester

Completed

MEK Inhibitor and Thoracic Radiotherapy Trial (MEKRT)

Non Small Cell Lung Cancer

United Kingdom
Northern Care Alliance NHS Foundation Trust
University of Manchester

Unknown

The Effect of Lactisole on the Responses to Glucose Solution

Blood Glucose | Hormones | Therapeutic Uses | Appetite

United Kingdom
University of Cambridge
Medical University of Graz; University Hospital Birmingham NHS Foundation Trust and other collaborators

Completed

24/7 Closed-loop in Older Subjects With Type 1 Diabetes (DAN06)

Hypoglycemia | Type 1 Diabetes Mellitus | Arrythmia

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Portsmouth... and other collaborators

Unknown

The Wessex Fit-4-Cancer Surgery Trial (WesFit)

Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Manchester Metropolitan University

Completed

Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance (PMVI-PiP)

Mitral Regurgitation | Mitral Valve Insufficiency

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

Completed

The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity

Tumor of Esophagus, Stomach and Duodenum

United Kingdom

Clinical Trials Sponsored by Central Manchester University Hospitals NHS Foundation Trust

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