Do Patients Suffering a Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?

Do Patients Suffering an Out-of-hospital Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?

A cardiac arrest is often preceeded by a varying period of physiological deterioration which if acted upon may prevent the cardiac arrest. We aim to review patients presenting to the ambulance service with cardiac arrest so see if they had contacted the ambulance service in the preceeding 48 hrs to understand if warning symptoms were missed or not acted upon appropriately.

Study Overview

• Status: Completed
• Conditions: Cardiac Arrest
• Intervention / Treatment: Diagnostic test: NEWS2 score

Detailed Description

The UK ambulance services are called to attend 60,000 out-of-hospital cardiac arrests (OHCA) each year. Hospital studies have shown that many patients who suffer an in-hospital cardiac arrest (IHCA) have been deteriorating for the preceeding 48 hrs and suggest that many IHCA are potentially avoidable if this deterioration is identified and actued on promptly. No similar study has been performed to see if patients suffering OHCA have also presented with warning signs in the preceeding 48 hrs that were overlooked.

• Study Type: Observational
• Enrollment (Actual): 200

Contacts and Locations

Study Locations

• United Kingdom
  • Hampshire
    • Otterbourne, Hampshire, United Kingdom, SO21 2RU
      • South Central Ambulance Service

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients calling for an emergency ambulance in the South Central Ambulance Service region, where an emergency ambulnace was dispatched and a patient intervention occurred.

Description

Inclusion Criteria:

• All patients seen by SCAS ambulance crews and suffering a cardiac arrest within the following 48 hrs

Exclusion Criteria:

• None

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Out-of-hospital cardiac arrest; Patients suffering an out-of-hospital cardiac arrest to who the ambulance service was requested to attend.	Diagnostic test: NEWS2 score; Patients seen by ambulance crews within the preceeding 48 hrs of their cardiac arrest will have a NEWS2 score performed to assess the level of physiological deterioration at the time of thei intial assessment.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Out-of-hospital cardiac arrest	Cardiac arrest following ambulance assessment	48 hours

Collaborators and Investigators

• Sponsor: University Hospital Southampton NHS Foundation Trust
• Collaborators: South Central Ambulance Service NHS Foundation Trust
• Investigators: Principal Investigator: Charles D Deakin, MD, Divisional Medical Director

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2018
• Primary Completion (Actual): February 19, 2020
• Study Completion (Actual): February 20, 2020

Study Registration Dates

• First Submitted: October 21, 2020
• First Submitted That Met QC Criteria: October 21, 2020
• First Posted (Actual): October 27, 2020

Study Record Updates

• Last Update Posted (Actual): April 13, 2022
• Last Update Submitted That Met QC Criteria: April 5, 2022
• Last Verified: February 1, 2020

More Information

Terms related to this study

• Keywords: Cardiac arrest; Ambulance; Triage; Deterioration
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest
• Other Study ID Numbers: 3724/18

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No