Clinical Trials Sponsored by Institut Guttmann

Total 74887 results

Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Fotemustine in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

France
Institut du Cancer de Montpellier - Val d'Aurelle

Suspended

Gemcitabine With Or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

Bladder Cancer

France
PIQUR Therapeutics AG
Hospital Universitari Vall d'Hebron Research Institute; Institut Català d'Oncologia and other collaborators

Completed

PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

Metastatic Breast Cancer

Spain, United Kingdom
Instituto Nacional de Cancer, Brazil
Cancer Research UK Cambridge Institute

Unknown

A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer (MEGA)

Breast Neoplasm

Brazil
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion (EBOVER)

Macular Edema | Retinal Vein Occlusion

Spain
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Enrolling by invitation

Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository (HiRO-HCM)

Cardiomyopathies | Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy | Familial Hypertrophic Cardiomyopathy

Canada
Karolinska Institutet
Region Stockholm; KTH Royal Institute of Technology

Active, not recruiting

Medication Repurposing to Stop Cognitive Decline in Dementia

Alzheimer Dementia | Dementia Disorders

Sweden
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Completed

Non-isotope Based Imaging Modalities vs Technetium-99m Single-Photon Emission Computed Tomography(99mTcSPECT) (MITNECB5)

Myocardial Ischemia

Canada
Karolinska Institutet
University of Nairobi; Kenya Medical Research Institute

Completed

Post-abortion Care and Contraceptive Counselling by Midwives or Physicians

Pregnancy

Kenya
Saint John's Cancer Institute
National Institutes of Health (NIH)

Completed

Multicenter Selective Lymphadenectomy Trial (MSLT)

Melanoma
National Cancer Institute, Naples
Baxter Healthcare Corporation; Fondazione IRCCS Istituto Nazionale dei Tumori... and other collaborators

Active, not recruiting

A Phase II Prospective, Single Blinded, Randomized Trial of Hemopatch Compared to Standard Techniques to Achieve Air Leak Control After Complex Thoracic Surgical Procedures (Hemopatch)

Thoracic Surgery Lung | Post-operative Thoracic Air Leak

Italy
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
Instituto Universitario de Oftalmobiología Aplicada...

Recruiting

Sphenopalatine Ganglion Stimulation for Ocular and Oral Dryness

Xerostomia | Dry Eye Disease

Spain
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Active, not recruiting

CLinical Utility of Early Intervention Including the 5-Step Precision Medicine (5SPM) Method in First-episode Psychosis: The CLUMP Project (CLUMP)

Psychosis

Spain
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images

Ocular Hypertension | Glaucoma | Glaucoma, Suspect

Spain
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Efficacy and Safety of a Treatment for Dry Eye Syndrome: Thealoz

Moderate Dry Eye Syndrome

Spain
Swiss Federal Institute of Technology
Instituto Venezolano de Investigaciones Cientificas

Completed

Effects of Vitamin A and Carotenoids on Iron Absorption

Iron Absorption

Venezuela
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Ottawa Hospital Research Institute and other collaborators

Completed

Promoting Organ Donor Registration in Family Physician Offices

Organ Donation | Registration for Deceased Organ Donation

Canada
Institut Pasteur

Not yet recruiting

Genetic Determinants of the Antiviral Immune Response in Oceanian Populations (GEDIPOP)

Virus

New Caledonia
Institut Curie

Not yet recruiting

Patient Experience and Quality of Life During the Surveillance Phase of Uveal Melanoma: A Prospective Multi-method Study (SALOME Quali)

Uveal Melanoma
Institut Curie

Recruiting

Study for the Reliability and Validity of the EORTC PATSAT-C33 and the EORTC OUT-PATSAT7 Questionnaires (PATSAT)

Cancer

France
Institut Curie

Recruiting

Digital Phenotyping in Women Over 70 Years of Age Treated for Breast Cancer With Any Type of Treatment (GrannyFit)

Breast Cancer

France
Institut Curie

Recruiting

Characterisation of the Immune Infiltrate and Molecular Features of Thymic Epithelial Tumors Tumors (TETs) (IMMUNO-TET)

Cancer

France
Institut Curie

Recruiting

Personalized First-line Chemotherapy Choice in Advanced Pancreatic Adenocarcinoma Using Transcriptomic Signatures (PACsign)

Carcinoma, Pancreatic Ductal | Prognosis

France
Institut Curie

Recruiting

ProActIF-01 Trial: Randomized Study of Evaluation of an Individualized Program of Nutrition and Adapted Physical Activity in Frail Patients With Advanced Lung or Digestive Cancers (ProActIF-01)

CANCER

France
Institut Curie

Recruiting

Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study. (OFOBA)

Breast Cancer

France
Institut Curie

Recruiting

Comparative Study of Diagnostic and Prognosis Biomarkers of Prostate Cancer in Liquid Biopsy (HOPE)

Prostate Cancer | Healthy Donors

France
Institut Curie

Recruiting

Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4 (ALCINA4)

Cancer

France
Institut Curie

Recruiting

Exenteration: Quality of Life Study and Rehabilitation Rate According to the Reconstruction Technique (ETRE) (ETRE)

Cancer

France
Institut Curie

Recruiting

Real Life Study Evaluating the Clinical and Organisational Impact of Moovcare® Lung Connected Medical Device in Lung Cancer Patients : REAL-MOOV-LUNG (REAL-MOOV-LUNG)

Lung Cancer

France
Institut Bergonié

Recruiting

Impact of Specific Monitoring of Intraoperative Analgesia Under General Anesthesia on Chronic Pain After Ovarian Cancer Surgery (MONIALC)

Ovarian Neoplasm

France
Institut Pasteur

Recruiting

Study of the Incidence of Jarisch-Herxheimer Reaction in Leptospirosis Patients in New Caledonia (LEPJARNC)

Leptospirosis | Jarisch Herxheimer Reaction

New Caledonia
Institut Curie

Recruiting

First-in-human Phase I to Evaluate PEP-010 as Single Agent and in Combination With Paclitaxel or With Gemcitabine (CleverPeptide)

Metastatic Solid Tumor Cancer

France
Institut Curie

Recruiting

Chemotherapy Monitoring by ctDNA in HER2- Metastatic Breast Cancer (MONDRIAN)

HER2-negative Metastatic Breast Cancer

France
Institut Pasteur

Recruiting

Creation of a Prospective Cohort of Healthy and Sick Subjects and of a Collection of Associated Biological Resources, for the Study of the Immune System and of Its Genetic and Environmental Determinants. (CoSImmGEn)

Immune System and Related Disorders

France
Institut Pasteur

Recruiting

Simian Foamy Virus Transmission to Humans

Simian Foamy Virus Infection (Disorder)

Cameroon
Institut Curie

Recruiting

Prospective Biobanking Study in Ovarian, Breast, Head and Neck and Cervical Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) (SCANDARE)

Cervical Cancer | Head and Neck Cancer | Ovarian Cancer | Triple-Negative Breast Cancer

France
Institut Bergonié

Recruiting

Regional Central Database Recording of Chronic Myeloid Leukemia (LMC)

Chronic Myeloid Leukemia

France
Institut Rafael

Completed

Survey of Sexual Health in Cancer Patients (S&C)

Integrative Oncology

France
Institut Curie

Terminated

Study to Assess the Impact of Personalized Coaching on the Time Period and Quality of Return to Work After Breast Cancer (OPTICOACH)

Breast Cancer | Surgery

France
Institut Rafael

Active, not recruiting

Patient Preference Between a Prefilled Syringe or a Prefilled Pen Device for Administration of Pegfilgrastim (PELGRAZ)

Patient Satisfaction | Patient Preference | Febrile Neutropenia, Drug-Induced

France
Institut Curie

Active, not recruiting

SHIVA02 - Evaluation of the Efficacy of Targeted Therapy Based on Tumor Molecular Profiling in Patients With Advanced Cancer Using Each Patient as Its Own Control (SHIVA02) (SHIVA02)

Cancer | Solid Tumor, Adult

France
Institut Curie

Active, not recruiting

The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers: Impact on Quality of Life, Care Pathways and Support for Caregivers (HDJ-SPI)

Cancer, Advanced

France
Institut Curie

Active, not recruiting

Improvement of Local Control in Skull Base, Spine and Sacral Chordomas Treated by Surgery and Protontherapy Targeting Hypoxic Cells Revealed by [18F]FAZA) PET/CT Tracers (PROTONCHORDE01)

Skull Base Chordoma | Vertebral Chordoma

France
Institut Curie

Completed

Use of Specific Genetic Alteration s of Tumoral Cells Identified by the Next Generation Sequencing Techniques (NGS) to Follow Peripheral Samples of Children With Metastatic and/or High Risk Solid Tumor - NGSKids (NGSKids)

Metastatic and/or High Risk Solid Tumor of Children

France
Institut Curie

Completed

Study of Circulating Tumoral DNA in Metastatic Choroidal Melanoma

Choroidal Melanoma, Diffuse

France
Institut Curie

Completed

Circulating Tumoral DNA in Choroidal Melanoma (ctDNA MU) (ctDNA MU)

Choroidal Melanoma

France
Institut Bergonié

Active, not recruiting

Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients (OPTIMUNELUNG)

Non Small Cell Lung Cancer

France
Institut Curie

Completed

MIRs 04 : Interpectoral Nerve Block With Ropivacaine Versus Placebo Before Breast Cancer Surgery

Malignant Neoplasm of Breast

France
Institut Curie

Active, not recruiting

Use of Virtual Reality Mask or Music Therapy for Analgesia and Anxiolytic Purpose When Totally IVAD for Chemotherapy Under Local Anesthesia (REVCCI)

Implanted Venous Access Device

France

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