Clinical Trials Sponsored by YM BioSciences

Total 1857 results

Zomagen Biosciences, Ltd

Completed

A Study to Evaluate VTX2735 in Patients With Cryopyrin-associated Periodic Syndrome (Explore)

Cryopyrin Associated Periodic Syndrome

United States
Brii Biosciences, Inc.

Withdrawn

A Safety and Efficacy Study of Human Monoclonal Antibodies, BRII-196 and BRII-198 for the Treatment of Patients With COVID-19

COVID-19

China
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Anwita Biosciences

Recruiting

Phase 1 Study of AWT020 in Advanced Cancer

Advanced Cancer

Australia
Aura Biosciences

Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma (CoMpass)

Ocular Melanoma | Uveal Melanoma | Choroidal Melanoma | Indeterminate Lesions

United States, Australia, United Kingdom
IDEAYA Biosciences

Recruiting

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | Advanced or Metastatic Solid Tumors

United States
DEKA Biosciences

Recruiting

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Kidney Cancer | Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Skin Cancer | Pancreas Cancer

United States
Spruce Biosciences

Recruiting

A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children With CAH

Congenital Adrenal Hyperplasia | 21-OHD

United States
Neurocrine Biosciences

Recruiting

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
IDEAYA Biosciences

Recruiting

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Solid Tumor

United States, Taiwan, Korea, Republic of, France, Spain, Australia, Germany
Persephone Biosciences

Recruiting

ARGONAUT: Stool and Blood Sample Bank for Cancer Patients

Colorectal Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Pancreas Cancer

United States
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Patients With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)

Congenital Adrenal Hyperplasia

United States, United Kingdom, France, Greece, Italy, Spain, Belgium, Canada, Germany, Poland
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
KBP Biosciences

Completed

Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects and Subjects With Renal Impairment

Healthy | Renal Insufficiency

United States
Neurocrine Biosciences

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (ERUDITE)

Schizophrenia

United States, Spain, Serbia, Czechia, Bulgaria, Mexico
Walden Biosciences

Completed

Single Ascending Dose Study of WAL0921 in Healthy Subjects

Healthy

United States
Persephone Biosciences

Active, not recruiting

My Baby Biome: Infant Stool Samples for Microbiome Health (MBB)

Dysbiosis

United States
Neurocrine Biosciences

Completed

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD) (SAVITRI)

Major Depressive Disorder

United States, Czechia, Bulgaria, Poland, Slovakia, Sweden
KBP Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Chronic Kidney Disease

United States
KBP Biosciences

Active, not recruiting

Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe CKD (Clarion-CKD)

Chronic Kidney Diseases

China, Spain, Australia, Hungary, Malaysia, United States, Germany, Bulgaria, Serbia, Hong Kong, Georgia, Bosnia and Herzegovina, Croatia, Czechia, South Africa, Canada, Israel, Korea, Republic of, Latvia, Lithuania, Poland, Taiwan
KBP Biosciences

Completed

Phase 1 Single Ascending Dose Study to Evaluate Safety, Tolerability and Pharmacokinetics of KBP-5074

Healthy
Novadip Biosciences

Active, not recruiting

NVD-003 in the Treatment of Congenital Pseudarthrosis of the Tibia

Congenital Pseudarthrosis of Tibia

Belgium, United States
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Estonia, Germany, Korea, Republic of, Latvia, Lithuania, Poland, Romania, Spain, Sweden, Turkey, Canada, Italy, United Kingdom
Sanguine Biosciences

Completed

A Biospecimen and Clinical Data Study on Patients for Drug & Biomarker Discovery

Multiple Sclerosis | Parkinson's Disease | Amyotrophic Lateral Sclerosis (ALS) | Alzheimer's Disease | Huntington's Disease

United States
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
Origin Biosciences

Completed

Safety & Efficacy Study of ORGN001 (Formerly ALXN1101) in Pediatric Patients With MoCD Type A Currently Treated With rcPMP

Molybdenum Cofactor Deficiency, Type A

United States, Australia, Netherlands, United Kingdom, Tunisia
Neurocrine Biosciences

Completed

Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD (TERPSIS)

Anhedonia | Major Depressive Disorder

United States, Puerto Rico
Asana BioSciences

Terminated

Study to Evaluate Long-Term Safety of ASN002 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Neurocrine Biosciences

Completed

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom, Canada
Asana BioSciences

Completed

Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema

Chronic Hand Dermatitis

United States, Canada
Asana BioSciences

Completed

Study to Evaluate ASN008 Topical Gel (TG)

Dermatitis, Atopic | Pruritus | Dermatitis Eczema

United States, Canada
Pyramid Biosciences

Completed

A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream

Psoriasis | Healthy Volunteers

United States
Pyramid Biosciences

Completed

A Formulation Bridging and Food Effect Study of PBI-200 in Healthy Volunteers

Formulation Bridging and Food Effect in Healthy Volunteers

United States
Ensysce Biosciences

Completed

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
Flame Biosciences

Withdrawn

FL- 101 Study in Non-Metastatic MIBC

Muscle Invasive Bladder Carcinoma
Neurocrine Biosciences

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 in Adults With Congenital Adrenal Hyperplasia

CAH - Congenital Adrenal Hyperplasia

United States
Neurocrine Biosciences

Terminated

Rollover Study for Continuing NBI-98854 Administration in Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

United States, Puerto Rico
Catalyst Biosciences

Terminated

A Natural History Study to Assess the Clinical Outcomes of Patients With Complement Factor I Deficiency-Mediated Disease

Recurrent Bacterial Infection, Autoimmune Disorder

United States
Flame Biosciences

Withdrawn

Phase 1/2a Study to Evaluate FL-301 in Patients With Advanced Solid Tumors

Gastric Cancer | Solid Tumor | Pancreas Cancer
Skyline Biosciences

Withdrawn

This Study is to Evaluate the Safety and Pharmacokinetics of SBS-101 in Patients With Oral Premalignant Lesions

Leukoplakia, Oral

United States
Catalyst Biosciences

Completed

Study of Coagulation Factor VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia A and B

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

Armenia, Georgia, South Africa, Poland, Russian Federation
Knopp Biosciences

Completed

Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211) (CL211)

Amyotrophic Lateral Sclerosis

United States
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
Knopp Biosciences

Completed

Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL201)

Amyotrophic Lateral Sclerosis

United States
Hope Biosciences

No longer available

Individual Patient Expanded Access IND of Hope Biosciences First Blood Relative Allogeneic Adipose-derived Mesenchymal Stem Cells (HB-adMSCs) for Pancreatic Cancer

Pancreatic Cancer

United States
Knopp Biosciences

Completed

Phase 3 Study of Dexpramipexole in ALS (EMPOWER)

Amyotrophic Lateral Sclerosis

United States, United Kingdom, Netherlands, Spain, Belgium, Germany, Australia, Sweden, France, Ireland, Canada
Knopp Biosciences

Completed

Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia (CS201)

Chronic Sinusitis With Nasal Polyps and Eosinophilia

United States
Neurocrine Biosciences

Completed

Persistence of Effect and Safety of Valbenazine for the Treatment of Tardive Dyskinesia

Tardive Dyskinesia (TD)

United States, Puerto Rico
Assembly Biosciences

Completed

A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection

Chronic Hepatitis B

New Zealand, United States, Canada

Clinical Trials Sponsored by YM BioSciences

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