Search clinical trials for: DAPT De-escalation

Total 310 results

M.D. Anderson Cancer Center
Cubist Pharmaceuticals LLC

Completed

Catheter Related - Gram Positive Bloodstream Infections

Bloodstream Infection

United States
Cubist Pharmaceuticals LLC

Terminated

Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)

Infective Endocarditis

United States
Oncurious NV
Beat Childhood Cancer

Completed

A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma

Relapsed or Refractory Medulloblastoma (MB), Neuroblastoma (NB), Ewing Sarcoma (ES) and Alveolar Rhabdomyosarcoma (ARMS)

United States
Icahn School of Medicine at Mount Sinai
AstraZeneca

Completed

Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention (TWILIGHT)

Cardiovascular Disease | Interventional Cardiology

United States
Medtronic Vascular

Completed

A Randomized Controlled Trial With Resolute Onyx in One Month Dual Antiplatelet Therapy (DAPT) for High-Bleeding Risk Patients (Onyx ONE)

Coronary Artery Disease

Korea, Republic of, Spain, Australia, Hong Kong, United Kingdom, Singapore, Thailand, Belgium, New Zealand, Sweden, France, Switzerland, Netherlands, Italy, Slovakia, Lithuania, Austria, Malaysia, Bulgaria, Ireland, Latvia, Norway, ...
Zhongnan Hospital

Unknown

A Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney

Infection | Outcome, Fatal

China
Hospices Civils de Lyon

Unknown

Description of Eosinophilic Pneumonia in BJI/PJI Treated by Daptomycin

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
Federation Francophone de Cancerologie Digestive

Terminated

De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer (HIGH-LIGHT)

Colorectal Neoplasms

France
Scripps Health
Medtronic

Completed

Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside) (SEASIDE)

Coronary Artery Disease | Coronary Thrombosis

United States
Shenyang Northern Hospital

Unknown

Optimal antiPlatelet Therapy for High Bleeding and Ischemic RISK Patients Trial (OPT-BIRISK)

Prolonged DAPT in ACS Patients With Hisk of Both Ischemic and Hemorrhage

China
CeloNova BioSciences, Inc.
ClinLogix. LLC

Terminated

COBRA SHIELD OCT Study

Stable Angina

Finland
Boston Scientific Corporation

Completed

EVOLVE Short DAPT Study

Coronary Artery Disease

United States, Germany, Latvia, Japan, Sweden, Brazil, Switzerland
McGill University Health Centre/Research Institute...

Completed

Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia (DASH)

Bacteremia | Methicillin Susceptible Staphylococcus Aureus Septicemia

Canada
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Unknown

The Efficacy and Safety of Daptomycin in the Treatment of Gram-positive Bacterial Infection.

Antibiotic

China
Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Comparison Three vs Twelve Months of Dual Anti-Platelet Therapy After Stent Implantation

Percutaneous Coronary Intervention | Drug-Eluting Stents

China
The First Affiliated Hospital with Nanjing Medical...

Unknown

OPTImal Management of Antithrombotic Agents: OPTIMA-5

Acute Coronary Syndrome (ACS)

China
Bergen University College
Helse-Bergen HF

Completed

Evaluation of Training in De-escalation

De-escalation Skills

Norway
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae (SIMPLIFY)

Enterobacteriaceae Infections

Spain
Bloodworks
National Blood Foundation

Unknown

Reversal of Dual Antiplatelet Therapy With Cold Stored Platelets (R-DAPT)

Bleeding | Platelet Dysfunction Due to Drugs | Platelet Dysfunction

United States
Second Hospital of Jilin University
Siping Central Hospital; Beihua University; Meihekou Central Hospital; Yanbian... and other collaborators

Unknown

Acute Myocardial Infarction Study in Northeastern China

Acute Myocardial Infarction

China
Heinrich-Heine University, Duesseldorf
German Research Foundation

Completed

Staphylococcus Aureus Bacteremia Antibiotic Treatment Options (SABATO)

Staphylococcus Aureus Infection

France, Germany, Netherlands, Spain, United Kingdom
Biosensors Europe SA
European Cardiovascular Research Center

Completed

e-BioMatrix 6 Month DAPT France

Ischemia | Stable Angina | STEMI | NSTEMI - Non-ST Segment Elevation MI | Coronary Artery Stenoses
University of Roma La Sapienza

Completed

Repetitive Assessement of PRECISE-DAPT Score (RE-SCORE)

Cardiovascular Diseases | Interventional Cardiology

Italy
University of Sao Paulo General Hospital

Completed

Evaluation of Platelet Aggregability in the Release of CABG in Patients With ACS With DAPT.

Bleeding

Brazil
Cubist Pharmaceuticals LLC

Completed

Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard Antibiotics

Gram-positive Bacterial Infections

United States
Yonsei University

Unknown

A Randomized Controlled Comparison Between One Versus More Than Six Months of Dual Antiplatelet Therapy After Biolimus A9-eluting Stent Implantation

Coronary Artery Disease

Korea, Republic of
CAMC Health System

Completed

Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis

MRSA Infections

United States
Cumberland Pharmaceuticals

Terminated

A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial

Bacteremia

United States
East and North Hertfordshire NHS Trust
University of Hertfordshire

Unknown

Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS (VaLiDate-R)

Acute Coronary Syndrome

United Kingdom
CirQuest Labs, LLC

Completed

Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation (SEARCH)

Acute Coronary Syndrome

United States
Catharina Ziekenhuis Eindhoven
Erasmus Medical Center

Completed

Mean Systemic Filling Pressure Continuous Diuretics Critical Care Patients

Heart Diseases | Heart Failure | Sepsis | Septic Shock | Surgery | Critically Ill

Netherlands
Cubist Pharmaceuticals LLC

Completed

Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia

Pneumonia, Bacterial
Cubist Pharmaceuticals LLC

Completed

Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia Due to S. Pneumoniae

Pneumonia, Bacterial
Cubist Pharmaceuticals LLC

Completed

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Gram Positive Infection | Concurrent Antibiotic Treatment

United States
Cubist Pharmaceuticals LLC

Completed

Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics

Gram Positive Bacterial Infection

United States
Chaosu Hu

Unknown

De-escalation Protocols in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Terumo Europe N.V.

Unknown

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry (e-Ultimaster)

Coronary Artery Disease

Netherlands, France, United Kingdom, Austria, Ireland, Spain, Bulgaria, South Africa, Israel, Hungary, Switzerland, Chile, Belgium, Japan, Argentina, Portugal, United Arab Emirates, Serbia, Malaysia, Brazil, India, Poland, Indonesia, ... and more
University Hospital, Ghent

Completed

DetermInants of Antimicrobial Use aNd De-escalAtion in Critical Care (DIANA) (DIANA)

Infection

Belgium
Humanitas Hospital, Italy

Unknown

Bioresorbable Polymer-Coated EES in Patients at High Bleeding Risk Undergoing PCI Followed by 1-Month DAPT (POEM)

Coronary Artery Disease | Acute Coronary Syndrome

Italy
Fudan University

Unknown

De-escalation Protocols in HPV-related Oropharyngeal Carcinoma in Chinese Populations

Oropharyngeal Carcinoma | De-escalation

China
University Hospital, Montpellier

Completed

Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients (DVN)

Surgical Site Infection | Infective Endocarditis | Mediastinitis | Infection Related to Ventricular Assist Device | Infection Related to Vascular Prothesis

France
Cardiovascular Academy Society, Turkey

Completed

Demographical and Clinical Profile of Patients on Dual Antıplatelet Therapy and Mean Precise-DAPT and DAPT Scores in Turkey

Anti-platelet Therapy

Turkey
University Hospital Tuebingen

Completed

Daptomycin Concentration in Drainage Fluid and Blood Samples of ICU Patients

Heart Assist Device

Germany
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
University of Bologna

Unknown

A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis

Invasive Candidiases | Abdominal Infection

Italy
Japan Cardiovascular Research Foundation
Otsuka Pharmaceutical Co., Ltd.

Completed

Cilostazol Stroke Prevention Study for Antiplatelet Combination (CSPS・com)

Noncardioembolic Cerebral Infarction

Japan
Yonsei University

Completed

DETErmination of the Duration of the Dual Antiplatelet Therapy by the Degree of the Coverage of The Struts on Optical Coherence Tomography From the Randomized Comparison Between Everolimus-eluting Stents(EES) Versus Biolimus A9-eluting Stents(BES) (DETECT-OCT)

Ischemic Heart Disease

Korea, Republic of
Ospedale Santa Croce-Carle Cuneo

Unknown

Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)

Platelet Aggregation Inhibitors
Federico II University

Unknown

Effects of Prolonged DAPT After Lower Extremity Percutaneous Transluminal Angioplasty (PTA) in Patients With LE-PAD (LONGDAPTPAD)

Peripheral Artery Disease

Italy
Diagram B.V.

Completed

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent (REDUCE)

Acute Coronary Syndrome

Search clinical trials for: DAPT De-escalation

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