Search clinical trials for: Hepatic Impairment,

Total 10215 results

Biogen

Completed

BG9928 in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196

Hepatic Insufficiency

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Pretomanid in Adults With Hepatic Impairment

Tuberculosis

United States
Universidad de Zaragoza

Recruiting

Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities

Mild Cognitive Impairment | Randomized Controlled Trial | Subjective Cognitive Impairment

Spain
Vanderbilt University
Tennessee Department of Education

Recruiting

Providing Access to the Visual Environment

Vision Impairment

United States
University of California, San Francisco
Federal University of Minas Gerais

Completed

Better Memory With Literacy Acquisition Later in Life

Memory Impairment

Brazil
Westat
United States Social Security Administration

Completed

Supported Employment Demonstration (SED)

Mental Impairment

United States
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
Loewenstein Hospital

Completed

Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment

Graphomotor Impairment

Israel
Porter Adventist Hospital

Terminated

Donepezil Memory Preservation Post ECT

Memory Impairment

United States
Stanford University
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Age-related Longitudinal Changes in Aviator Performance

Memory Impairment

United States
US Department of Veterans Affairs

Completed

Restricted Useful Field View as a Risk Factor in Older Adults

Vision Impairment

United States
Intercept Pharmaceuticals

Completed

Hepatic Impairment Trial of Obeticholic Acid

Hepatic Impairment

United States
VA Office of Research and Development

Not yet recruiting

User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems (Squishycushion)

Mobility Impairment

United States
Ufuk University

Completed

Effects of Single-task Versus Dual-task Training on balancePERFORMANCE

Balance Impairment
Dr. Jose Antonio SERRA-REXACH
Instituto de Salud Carlos III

Completed

Physical Training in Hospitalized Elderly (AGECAR)

Functional Impairment

Spain
David Merrill, MD, PhD

Completed

Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints (MET)

Memory Impairment

United States
Neurolgy Institute for Brain Health and Fitness
DSM Nutritional Products, Inc.

Unknown

Cerebrovascular and Cognitive Improvement by Resveratrol (resVida) and Fruitflow-II (CCIRF-II) (CCIRF-II)

Memory Impairment

United States
Yale University

Completed

The Effects of Minocycline in Humans

Memory Impairment

United States
University of Manitoba

Unknown

Examining the Effect of a Simple Memory Tool

Memory Impairment

Canada
University of Manitoba

Unknown

Memory Intervention for Older Adults - (Social) (Social)

Memory Impairment
Gilead Sciences

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Chronic Hepatitis C

United States, Puerto Rico
University Hospital, Bonn
Maximilian Kiebs, M.Sc. - University Hospital Bonn (Department of Medical...

Recruiting

Prediction of the Cognitive Effects of Electroconvulsive Therapy Via Machine Learning and Neuroimaging (CoEffECT)

Depression | Cognitive Impairment | Memory Impairment | ECT

Germany
Wayne State University
St Vincent's Hospital; University of California, San Francisco Fresno

Completed

Cantharone for the Treatment of Perenial Warts

Wart, Genital
National Jewish Health

Completed

IV Colistin for Pulmonary Exacerbations: Improving Safety and Efficacy

Cystic Fibrosis

United States
Sichuan Haisco Pharmaceutical Group Co., Ltd
The First Affiliated Hospital of Zhengzhou University

Completed

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions

Chronic Renal Impairment

China
AstraZeneca

Recruiting

A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693

Hepatic Impairment

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Study to Evaluate Orelabrutinib Tablets in Subjects With Hepatic Impairment and Healthy Subject

Hepatic Impairment

China
CTI BioPharma
PPD

Recruiting

Study to Evaluate the Safety, Tolerability, and PK of Pacritinib

Hepatic Impairment

United States
Eisai Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

Hepatic Impairment

Japan
Novartis Pharmaceuticals

Completed

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Hepatic Impairment

Hungary
Chipscreen Biosciences, Ltd.

Completed

Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

China
SK Life Science, Inc.

Completed

Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment

Hepatic Impairment

Poland, Slovakia
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Hepatic Impairment
Institut de Recherches Internationales Servier

Completed

A Study of Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function

Hepatic Impairment

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
Pfizer

Completed

Single-Dose PK and Safety Study of GBT440 in Subjects With Hepatic Impairment

Hepatic Impairment

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Hepatic Impairment

Hepatic Impairment

China
Concert Pharmaceuticals

Completed

Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543

Hepatic Impairment

United States
Janssen Research & Development, LLC

Terminated

A Study of JNJ-53718678 in Participants With Hepatic Impairment

Hepatic Impairment

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics of BAF312 in Patients With Hepatic Impairment

Hepatic Impairment

Hungary, Russian Federation
Sichuan Haisco Pharmaceutical Group Co., Ltd
The First Hospital of Jilin University

Completed

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Hepatic Impairment

Hepatic Impairment

China
Novartis Pharmaceuticals

Completed

INC280 in Healthy Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function

Hepatic Impairment

United States
Novartis Pharmaceuticals

Completed

A Trial to Evaluate the Pharmacokinetics of ABL001 in Healthy and Hepatic Impaired Subjects

Hepatic Impairment

United States
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, United States, Hungary
Novartis Pharmaceuticals

Terminated

Pharmacokinetics of Dabrafenib in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989

Hepatic Impairment

Germany
Celgene

Completed

A Study to Assess the Pharmacokinetics of Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment.

Hepatic Impairment

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment

Hepatic Impairment

Switzerland
Pfizer

Completed

A Hepatic Impairment Study for PF-04965842.

Hepatic Impairment

United States

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