Search clinical trials for: IDH1/2

Total 47770 results

Indiana University

Completed

Rapid SARS-CoV-2 IgG Antibody Testing in High Risk Healthcare Workers (COVID-Antibody)

SARS-CoV-2

United States
Peking University
Centers for Disease Control and Prevention, China; Beijing Pinggu District... and other collaborators

Completed

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination (Trial 2)

SARS-CoV-2

China
Assistance Publique - Hôpitaux de Paris

Completed

NOsocomial Dissemination Risk of SARS-Cov2 (NODS-Cov2)

Sars-CoV2

France
University Hospital, Montpellier
societe SkillCell - 97198 Jarry; CNRS Alcediag UMR9005 - societe Sys2Diag -...

Completed

Evaluation of Quickly Diagnostic Saliva Tests for SARS-CoV-2 (EasyCoV)

SARS-CoV-2

France
CytRx

Withdrawn

A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS

Amyotrophic Lateral Sclerosis

United States, Canada
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Recruiting

Clinical Trail of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021) in Participants Aged 18 Years and Older

SARS-CoV-2

Pakistan
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Not yet recruiting

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

SARS-CoV-2
AIM Vaccine Co., Ltd.

Not yet recruiting

Clinical Trial of SARS-CoV-2 mRNA Vaccine(LVRNA009) as Heterologous Booster in Islamabad

SARS-CoV-2

Pakistan
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Potential Anti-tumor Effects of SSGJ-705 in Patients With Advanced or Metastatic HER2-expressing Solid Tumors

Receptor, ErbB-2
University of Pennsylvania
Inovio Pharmaceuticals

Recruiting

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

BRCA1/2 Mutation

United States
Ridgeback Biotherapeutics, LP
Merck Sharp & Dohme LLC

Completed

The Safety of Molnupiravir (EIDD-2801) and Its Effect on Viral Shedding of SARS-CoV-2 (END-COVID)

SARS-CoV 2

United States
Peking University
Centers for Disease Control and Prevention, China; Beijing Pinggu District... and other collaborators

Completed

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination (Trial 1)

SARS-CoV-2

China
Arcturus Therapeutics, Inc.

Completed

Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects

SARS-CoV-2

Singapore
Washington University School of Medicine
Gateway for Cancer Research; Servier Hellas Pharmaceuticals Ltd.

Recruiting

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Clonal Cytopenia of Undetermined Significance

United States
Chinese PLA General Hospital

Unknown

Treatment of Chemotherapy Refractory Human Epidermalgrowth Factor Receptor-2( HER-2) Positive Advanced Solid Tumors (CART-HER-2)

Advanced HER-2 Positive Solid Tumors | Chemotherapy Refactory | HER-2 Antibody Inhibitor Therapy Refactory

China
Merrimack Pharmaceuticals

Completed

A Study of MM-111 in Combination With Multiple Treatments in Patients With HER2 Positive Cancer

HER-2 Gene Amplification

United States
Centre Hospitalier St Anne
Etablissement Public de Santé Barthélemy Durand; Groupe Hospitalier Paul Guiraud

Not yet recruiting

The IM-ZBULLE Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate (IM-ZBULLE)

Schizophrenia; Psychosis

France
Invibio Ltd
In2Bones

Recruiting

A Post-market Clinical Study to Evaluate the Safety and Performance of the Carbon Fibre Reinforced Polyetheretherketone Metatarso-Phalangeal (MTP) Plate (CoLink® PCR MTP Plate) for the Treatment of Hallux Rigidus

Hallux Rigidus

United States
Turkish Society of Anesthesiology and Reanimation

Recruiting

Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy

Malnutrition | Lung Cancer | Nutritional Deficiency

Turkey
Eli Lilly and Company
Loxo Oncology, Inc.

Active, not recruiting

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Acute Myeloid Leukemia (AML) | Chronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS) | Myeloproliferative Neoplasms (MPNs)

United States, Spain, Korea, Republic of, France, Taiwan, Australia, Belgium, Singapore, Israel, Canada, Germany, Finland
CStone Pharmaceuticals

Completed

A China Bridging Study of Ivosidenib in r/r AML Subjects With an IDH1 Mutation

Relapsed or Refractory Acute Myeloid Leukemia

China
Memorial Sloan Kettering Cancer Center
Phenogen Sciences

Recruiting

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Genetic Testing | BRCA1/2

United States
Massachusetts General Hospital
GlaxoSmithKline

Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

Recurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 Mutation

United States
Vanderbilt-Ingram Cancer Center
Astex Pharmaceuticals, Inc.; Forma Therapeutics, Inc.

Withdrawn

ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome
University Hospital, Strasbourg, France

Completed

Seroprevalence of SARS-CoV-2 in Strasbourg University Hospital, Strasbourg, France (COVID-19) (SeroCoV-HUS)

SARS-CoV-2 Serological Status | SARS-CoV-2 Seroprevalence

France
Verrica Pharmaceuticals Inc.
BioClinica, Inc.; Paidion Research, Inc.; Instat Consulting, Inc.; ALMAC Clinical...

Completed

Cantharidin and Occlusion in Verruca Epithelium (COVE-1)

Skin Diseases | Virus Diseases | DNA Virus Infections | Skin Diseases, Infectious | Warts | Papillomavirus Infections | Skin Diseases, Viral | Tumor Virus Infections | Common Wart | Verruca Vulgaris | Warts Hand | Verruca

United States
Massachusetts General Hospital
National Cancer Institute (NCI)

Active, not recruiting

Proton Radiation Therapy for Gliomas

Low Grade Glioma | WHO Grade 3 Glioma With IDH1 Mutation | WHO Grade 3 Glioma With 1p/19q Codeletion

United States
Xijing Hospital
Ningbo No.2 Hospital

Recruiting

PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients

COVID-19 | Postoperative Complications | Post Traumatic Stress Disorder

China
Azienda Sanitaria Locale Napoli 2 Nord

Recruiting

ProSpectic Italian Laparoscopic Hybrid mEsh hErnia Repair in Obese patientS Trials (PSICHE-EROS)

Obesity | Uncomplicated Ventral Incisional Hernia

Italy
Bond Avillion 2 Development LP
Parexel

Active, not recruiting

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Asthma

United States
M.D. Anderson Cancer Center

Recruiting

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Hematopoietic and Lymphoid System Neoplasm | Myeloproliferative Neoplasm

United States
Neonc Technologies, Inc.

Recruiting

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

Glioblastoma Multiforme

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Italian Registry on the Prevalence of IDH1/IDH2 Mutations in Patients With Acute Myeloid Leukemia

AML, Adult

Italy
National Institute of Public Health, Cambodia
Emory University; World Vision International; World Vision, Hong Kong; World Vision...

Completed

Innovative Nutrition and mHealth Evidence Building Project

Underweight Children Aged 6-23 Month Old (WAZ < -1)

Cambodia
Eleven Biotherapeutics

Completed

Phase 3 Study of EBI-005 in Dry Eye Disease (EBI-005)

Dry Eye Disease (DED)

United States
Zhongnan Hospital

Recruiting

The Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (SYS6006) as Heterologous Booster in Participants Aged 18 Years and Older Vaccinated With Inactivated SARS-CoV-2 Vaccine

SARS-CoV-2 | Safety | Immunotoxicity

China
Horizon Pharma USA, Inc.

Completed

Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism

Aldehyde Dehydrogenase-2 (ALDH2) Deficiency

United States
Izmir Bakircay University

Not yet recruiting

Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery

Quality of Life | Pain, Postoperative | Disability Physical

Turkey
University Hospital, Montpellier
Fondation Jérôme Lejeune; association autour des Williams; réseau de santé Maladies...

Unknown

Cognitive and Behavioral Therapy of Anxiety in Williams Syndrome (WILL-COPE)

Anxiety | Williams Syndrome

France
Charles University, Czech Republic

Unknown

Fluid Responsiveness in Septic Shock Evaluated by Caval Ultrasound Doppler Examination (FRIEND)

Septic Shock | Vein Collapsibility | Intravascular Doppler | Volume Responsiveness in Septic Shock

Czechia
Affiliated 2 Hospital of Nantong University

Recruiting

Artificial Intelligence Model for Traumatic Cervical Spinal Cord Injury Based on Radiomics and Genomics

Spinal Cord Injuries

China
RenJi Hospital
Ningbo No.2 Hospital

Not yet recruiting

Construction of Symptom Network in Maintenance Hemodialysis Patients

Hemodialysis Complication | Symptoms and Signs | Hemodialysis-Associated Pruritus | Symptom Cluster

China
Xijing Hospital
Ningbo No.2 Hospital

Recruiting

Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial) (COIN)

Postoperative Complications

China
Azienda Sanitaria Locale Napoli 2 Nord

Recruiting

Use of Resorbable Prosthetic Mesh "Ante Rectus" as Prevention of Parastomal Hernia.

Parastomal Hernia

Italy
Peyrachon Romane

Enrolling by invitation

Exercise Intervention for Patients With Cancer Cachexia: Effects of a 12-week Program and One-year Follow-up. (2CAPA)

Cachexia-Anorexia Syndrome

France
Azienda Sanitaria Locale Napoli 2 Nord

Completed

Early Surgical Outcomes in the Use of Hybrid Mesh for Incisional Hernia Repair: Results From a Multicenter Italian Study (SHIELD)

Hernia | Incisional Hernia | Laparoscopic

Italy
Azienda Sanitaria Locale Napoli 2 Nord

Enrolling by invitation

Sleeve Gastrectomy: Outcome, Morbidity and Mortality. A Multicentric Retrospective Trial (PSICHE)

Morbid Obesity
Charles University, Czech Republic

Active, not recruiting

Evaluation of the LMWH Thromboprophylaxis in Pregnancy

Pregnancy

Czechia
Charles University, Czech Republic

Completed

Dynamic Parameters in Evaluation of Fluid Responsiveness

Surgery | Hypotension | Hypovolemia

Czechia
Eastern Mediterranean University

Not yet recruiting

The Effect of Laughter Yoga on Self-Care, Quality of Life and Stress Level in Menopause

Stress | Menopause | Laughter | Self

Cyprus

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