Search clinical trials for: Moderate to severe wrinkles and folds such as nasolabial folds

Total 489226 results

Boehringer Ingelheim

Completed

Postmarketing Surveillance Study of Anticholinergics - Prescribing Pattern and Therapeutic Long Term Value in Patients Suffering From Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Hanlim Pharm. Co., Ltd.

Completed

Study of Tisporin Eye Drops Group and Restasis Eye Drops Group After Treatment, Each Treatment Group Comparisons for Evaluation of Efficacy and Safety in Moderate to Severe Dry Eye Disease (HL_TSPR_302)

Dry Eye Syndromes

Korea, Republic of
Croma-Pharma GmbH
FGK Clinical Research GmbH

Completed

Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess® VOLUME in Nasolabial Folds

Nasolabial Folds

Austria
Across Co., Ltd.

Completed

Clinical Study to Evaluate the Efficacy and Safety of Dermalax Implant Plus

Correction of Nasolabial Folds

Korea, Republic of
Merz North America, Inc.

Completed

Belotero Post Approval Study

Nasolabial Folds

United States
Singapore National Eye Centre

Completed

Reproducibility of Anterior Segment Optical Coherence Tomography (AS-OCT) for Imaging Conjunctivochalasis

Dry Eyes

Singapore
Photocure

Completed

Photoactive Porphyrins (PAP) Levels After Topical Visonac Application in Acne Patients

Acne Vulgaris

United States
Revance Therapeutics, Inc.

Completed

A 4-Arm Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Revance Therapeutics, Inc.

Completed

Safety Study of Two Repeat Doses of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Revance Therapeutics, Inc.

Completed

Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Lateral Canthal Lines

United States
Wenzhou Medical University

Completed

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease

Moderate to Severe Dry Eye Syndrome

China
Revance Therapeutics, Inc.

Completed

Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Revance Therapeutics, Inc.

Completed

Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Revance Therapeutics, Inc.

Completed

Efficacy and Safety Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
The New York Eye & Ear Infirmary

Completed

Pilot Evaluation of Platelet Rich Fibrin Matrix (PRFM) for the Correction of Nasolabial Folds

Nasolabial Folds

United States
Elastagen Pty Ltd

Completed

Split-face Comparison Study to Assess ELAPR Compared to Juvéderm® for the Treatment of Nasolabial Folds

Aging

Australia
Alcon Research

Completed

To Evaluate the Physical Effects of Systane(R) Lubricant Eye Drops Compared to Refresh Tears(R) Lubricant Eye Drops

Dry Eye

India
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles

Bilateral Nasolabial Fold Wrinkles

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen Therapy in the Treatment of Nasolabial Fold Wrinkles

Bilateral Nasolabial Fold Wrinkles

United States
Alcon Research

Completed

A Multi-Site Post Marketing Surveillance Study for Systane in Indian Patients

Moderate to Severe Dry Eye
Alcon Research

Completed

Evaluate Artificial Tear Efficacy in Moderate to Severe Dry Eye

Dry Eye
Alcon Research

Completed

Systane Clinical Experience Study

Dry Eye Syndrome
Mentor Worldwide, LLC

Completed

PREVELLE Shape (CX002) Dermal Filler Protocol

Correction of Nasolabial Folds and Lip Augmentation

United States
Steven Fagien

Completed

Comparative Study of Reconstituted JUVÉDERM® Ultra vs COSMODERM® 1 for Lip and Cheek Lines, Folds or Wrinkles (JUVE_COSMO_1)

Intrinsic Aging of Skin

United States
Allergan

Completed

Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome

Arthritis, Rheumatoid | Lupus Erythematosus, Systemic | Scleroderma, Systemic | Keratoconjunctivitis Sicca | Sjogren's Syndrome

United States
University of Zagreb

Completed

The Effect of Ocular Lubricant Eyedrops on Lid Parallel Conjunctival Folds and Other Signs and Symptoms of Dry Eye (LIPCOF)

Dry Eye Syndromes

Croatia
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye Syndrome

Moderate to Severe Dry Eye Syndrome

France
The Plastic Surgery Foundation

Completed

A Trial of Skin Care Protocols for Facial Resurfacing (SPAR)

Facial Photo Damage | Periocular Fine Wrinkles | Perioral Fine Wrinkles

United States
Chulalongkorn University
Allergan

Unknown

Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes

Dry Eye

Thailand
Merz Pharmaceuticals GmbH

Completed

Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds

Nasolabial Folds

Germany
AbbVie

Not yet recruiting

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
Grupo Espanol de Trabajo en Enfermedad de Crohn...
Pfizer

Recruiting

An Active Surveillance, Post-Authorization Study to Characterize the Safety of Tofacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in the Real-World Setting Using Data From the United Registries for Clinical Assessment and Research (UR-CARE) in the European Union (EU) (PASS TOFA)

Ulcerative Colitis

Belgium, Bulgaria, Greece, Lithuania
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Hospital Universitario La Paz
Hospital Universitario del Henares, Madrid, Spain

Not yet recruiting

CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea (CPAPLIP)

Dyslipidemias | Sleep Apnea | Hyperuricemia
AbbVie

Not yet recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

Atopic Dermatitis
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

Clinical Study of Trilinolein Cream for Prevention of Relapse in Remission of Moderate-to-severe Atopic Dermatitis.

Atopic Dermatitis
RemeGen Co., Ltd.

Not yet recruiting

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)

Systemic Lupus Erythematosus
Abivax S.A.

Not yet recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease (ENHANCE-CD)

Moderately to Severely Active Crohn Disease
Medical University of Lodz
Poznan University of Medical Sciences; Medical Research Agency, Poland; Clinical... and other collaborators

Not yet recruiting

Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis (COMBO-UC)

Inflammatory Bowel Diseases | Ulcerative Colitis
AstraZeneca

Not yet recruiting

Phase IIa Study Evaluating AZD7798 in Crohn's Disease (AMALTHEA)

Moderate to Severe Crohn's Disease

United States, Vietnam, Turkey, Malaysia, Taiwan, Spain, Germany, Italy, Chile, Slovakia, Brazil, Japan, Bulgaria, Ukraine, South Africa, Argentina, Australia, Romania, Austria, Mexico, Sweden
Qilu Pharmaceutical (Hainan) Co., Ltd.

Recruiting

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
AbbVie

Recruiting

An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Regina Elena Cancer Institute

Recruiting

Analysis and Evaluation of Smoking Treatment With Cytisine

Moderate or Severe Tobacco Use Disorder

Italy
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Apollo Therapeutics Ltd

Recruiting

A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis

Dermatitis | Eczema | Atopic Dermatitis | Atopic | Eczema, Atopic | Dermatologic Disease | Eczema Atopic Dermatitis

United States, Canada
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China

3

Subscribe