Search clinical trials for: Phase I/II

Total 18499 results

MediLink Therapeutics (Suzhou) Co., Ltd.

Not yet recruiting

A Phase 1 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors

Advanced Solid Tumors

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Dose Escalation Study of Intravenous VX-993 in Healthy Adults

Pain

United States
Universitat Politècnica de Catalunya
Institut Català de la Salut; Consorci Hospitalari de Vic; EAP Vic (CAP Remei); Associació...

Recruiting

Effectiveness of a Rehabilitation Exercise Plan at Home to Treat Post-stroke Patients in the Chronic Phase

Stroke | Physical Disability | Motor Disorders

Spain
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
PHARMENTERPRISES LLC

Not yet recruiting

Study to Evaluate the Efficacy and Safety of XC243 in Patients With Exacerbation of Chronic Cystitis

Cystitis

Russian Federation
GenVivo, Inc.

Recruiting

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery

Anesthesia

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain

United Kingdom
Lund University Hospital

Not yet recruiting

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI) (PERELI)

Dedifferentiated Liposarcoma

Sweden, Norway
Ocugen

Recruiting

A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa (liMeliGhT)

Retinitis Pigmentosa

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis

Hepatocellular Carcinoma | Radiotherapy | Pembrolizumab | Tumor Thrombosis

China
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

A Randomized, Double-blind,Dose-escalating, Single-dose, Oral Phase I Clinical Study of Flunotinib Healthy People

Healthy Person

China
BioRay Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase I Study of BR115 for Injection Alone in Subjects With Advanced Solid Malignancies

Advanced Solid Malignancies

China
Luye Pharma Group Ltd.

Not yet recruiting

A Phase 1, SAD Study to Evaluate the Safety and Tolerability of LY03017

Negative Symptoms of Schizophrenia | Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis | Hallucinations and Delusions Associated With Parkinson Disease Psychosis

China
Ascentage Pharma Group Inc.

Not yet recruiting

A Pivotal Phase 3 Study of APG-2575 (Lisaftoclax) Combined With Azacytidine in the Treatment of Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
Belite Bio, Inc

Not yet recruiting

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease (DRAGON II)

Stargardt Disease 1 | STGD1

United States
Novartis Pharmaceuticals

Not yet recruiting

A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Mixed Dyslipidemia | Primary Hypercholesterolemia
Tolmar Inc.
ICON plc

Recruiting

A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months

Hypogonadism

United States
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.

Acute-On-Chronic Liver Failure

India
Letolab

Not yet recruiting

Phase II Clinical Study of LTC004 in Patients With mCRC

Locally Advanced or Metastatic CRC
MediLink Therapeutics (Suzhou) Co., Ltd.
Hoffmann-La Roche

Recruiting

A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
Shanghai Escugen Biotechnology Co., Ltd

Not yet recruiting

A Phase III Study of ESG401 for Locally Advanced or Metastatic HR+/HER2- Breast Cancer

Metastatic Breast Cancer

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Phase 1 Study in Healthy Participants and Participants With Kidney Dysfunction

Healthy

China
Milton S. Hershey Medical Center

Not yet recruiting

Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2

Melanoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Liver Cancer | Genito-Urinary Cancer

United States
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK120 in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Pyramid Biosciences

Not yet recruiting

A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors

Solid Tumor

United States
Letolab

Not yet recruiting

Phase II Clinical Study of LTC004 in Patients With Advanced Sarcoma

Unresectable or Metastatic Sarcoma
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
Blue Blood Biotech Corp.

Recruiting

Phase II Study of BB-101 for the Treatment of Diabetic Lower Leg and Foot Ulcers

Diabetic Foot Ulcer

Taiwan
Norroy Bioscience Co., LTD

Recruiting

A Phase 1/2 Study of 177Lu-NYM032 Injection in mCRPC

Metastatic Castration-resistant Prostate Cancer

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour

Advanced Malignant Tumour
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Myeloid Malignancies | Lymphodepleting Chemotherapy

United States
Azienda Ospedaliera di Padova

Recruiting

Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years (Over70-LT)

Liver Transplantation | Old Age | End Stage Liver DIsease

Italy
Zai Lab (Hong Kong), Ltd.
Zai Lab (US) LLC

Recruiting

A Phase 2 Study of ZL-1102 in Patients With Chronic Plaque Psoriasis

Plaque Psoriasis

Australia
BioMarin Pharmaceutical

Not yet recruiting

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Idiopathic Short Stature
Delta-Fly Pharma, Inc.

Not yet recruiting

Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

United States
Cancer Research UK
UCB Biopharma SRL

Not yet recruiting

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

Uterine Cervical Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Advanced Solid Tumours | Carcinoma, Renal Cell (Clear Cell Only) | Stomach Neoplasms...

United Kingdom
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
University of Roma La Sapienza

Recruiting

Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study

Inguinal Hernia | Post Operative Pain

Italy
Resolution Therapeutics Limited

Recruiting

Study in Patients With Decompensated Liver Cirrhosis (OPAL)

Liver Cirrhosis

United Kingdom
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

Ankylosing Spondylitis

China
Far Eastern Memorial Hospital

Not yet recruiting

Effect of Dialysis-specific Therapeutic Diet on Biochemical Parameters in Dialysis Patients

End-Stage Kidney Disease
Wingate Institute
Weizmann Institute of Science; Kaplan Medical Center; Ministry of Innovation,...

Recruiting

Identifying Periods of High Training Load Considering the Menstrual Cycle Phases in Elite and Non-elite Female Athletes

Physical Activity | Athletes | Menstrual Cycle

Israel
Nanfang Hospital, Southern Medical University

Not yet recruiting

To Optimize Therapeutic Procedures of DPMAS in ACLF Patients: a Prospective, Sigle Arm and Multicenter Study

Acute-On-Chronic Liver Failure
Rigshospitalet, Denmark

Not yet recruiting

Early Detection of Complications During Immunotherapy for Haematological Malignancy

Hematologic Cancer | CRS - Cytokine Release Syndrome
Amgen

Not yet recruiting

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Asthma
Novartis Pharmaceuticals

Not yet recruiting

A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers

Ovarian Cancer | Lung Cancer

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