Search clinical trials for: Primary sclerosing cholangitis

Total 16502 results

Peking Union Medical College Hospital

Recruiting

Clinical Research of UCDA Reducing Medication Regimen in Stable PBC (UCDA PBC)

Primary Biliary Cholangitis

China
West China Hospital

Recruiting

Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II

Hepatitis, Autoimmune | Primary Biliary Cholangitis

China
University of Aarhus
Aarhus University Hospital; Hvidovre University Hospital

Recruiting

Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

Denmark
West China Hospital

Recruiting

Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy

Hepatitis, Autoimmune | Immunosuppression | Primary Biliary Cholangitis

China
GlaxoSmithKline

Recruiting

Linerixibat Long-term Safety, and Tolerability Study (LLSAT)

Cholestasis

United States, France, Japan, United Kingdom, Bulgaria, Germany, Greece, Italy, China, Argentina, Belgium, Brazil, Canada, Czechia, Israel, Mexico, Poland, Russian Federation, Spain, Switzerland
University of Leipzig
Hannover Medical School; RWTH Aachen University; Academisch Medisch Centrum -... and other collaborators

Recruiting

Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis (PBC-Cohort)

Primary Biliary Cholangitis | PBC

Germany
CymaBay Therapeutics, Inc.

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Korea, Republic of, Belgium, Spain, France, Switzerland, Romania, United Kingdom, Austria, Israel, Australia, Argentina, Canada, Chile, Germany, Greece, Hungary, Italy, Mexico, Netherlands, Poland, Czechia, New Zealand, Turke... and more
OHB Neonatology Ltd.

Recruiting

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

Finland, United States, France, Italy, United Kingdom, Germany, Canada, Ireland, Japan, Netherlands, Portugal, Spain, Sweden
Humanity and Health Research Centre
Beijing 302 Hospital

Recruiting

Performance of Scoring Systems in Chinese Patients With Primary Biliary Cholangitis (PBC) on Ursodeoxycholic Acid

Primary Biliary Cholangitis (PBC)

China
Fondazione Epatocentro Ticino

Recruiting

Swiss Primary Biliary Cholangitis Cohort Study

Liver Cirrhosis, Biliary

Switzerland
University of Birmingham
NHS Blood and Transplant

Recruiting

Selected Mesenchymal Stromal Cells to Reduce Inflammation in Patients With PSC and AIH (Merlin)

Cholangitis, Sclerosing | Hepatitis, Autoimmune

United Kingdom
Xiaoli Fan

Recruiting

Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome

Cholangitis | Hepatitis, Autoimmune | Cholestasis | Liver Cirrhosis, Biliary

China
West China Hospital

Recruiting

Primary Prophylaxis of Gastric Variceal Bleed

Gastric Varices

China
AgoneX Biopharmaceuticals, Inc.

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis

Migraine Prophylaxis
Calliditas Therapeutics Suisse SA

Active, not recruiting

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness (TRANSFORM)

Primary Biliary Cholangitis | Liver Stiffness

United States, Spain, France, Australia, Israel, Canada, Switzerland, Italy, New Zealand, Germany, Poland, Greece, United Kingdom, Belgium, Austria, Czechia, Hungary, Sweden
Zydus Therapeutics Inc.

Active, not recruiting

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis (EPICS-III)

Primary Biliary Cholangitis

United States, Argentina, Iceland, Turkey
Ipsen

Active, not recruiting

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) (ELATIVE)

Primary Biliary Cirrhosis

United States, France, Spain, Belgium, Germany, Switzerland, Brazil, United Kingdom, Argentina, Canada, Chile, Italy, South Africa, Turkey
HighTide Biopharma Pty Ltd

Completed

Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis (PRONTO-PBC)

Biliary Tract Diseases | Cholangitis | Cholestasis | Primary Biliary Cholangitis | Primary Biliary Cirrhosis | Bile Duct Stricture

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Rhabdomyosarcoma | Alveolar Rhabdomyosarcoma | Embryonal Rhabdomyosarcoma | Botryoid-Type Embryonal Rhabdomyosarcoma | Sclerosing Rhabdomyosarcoma | Spindle Cell Rhabdomyosarcoma

United States, Canada, Puerto Rico, Australia, New Zealand
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

Primary Biliary Cholangitis

Netherlands, United Kingdom, Korea, Republic of, Germany, Australia, Estonia, Belgium, France, Czechia, Croatia, Greece, Hungary, Israel, Lithuania, Norway, Poland, Spain
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Primary Biliary Cholangitis

United States
Gannex Pharma Co., Ltd.

Completed

Study to Evaluate the Safety and Efficacy of ASC42 Tablets in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Yilihamu·Abilitifu

Completed

The Effectiveness of Combining Ursodeoxycholic Acid With Vitamin D in Treating Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Medical University of Graz

Active, not recruiting

Secondary Sclerosing Cholangitis in Critically Ill Patients (SSC-CIP)

Secondary Sclerosing Cholangitis

Austria
COUR Pharmaceutical Development Company, Inc.

Active, not recruiting

Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
Target PharmaSolutions, Inc.

Active, not recruiting

A 5-year Longitudinal Observational Study of Patients With Primary Biliary Cholangitis

Biliary Cirrhosis, Primary

United States
University of Alberta
Merck Sharp & Dohme LLC

Completed

Combination Antiretroviral Therapy (cART) for PBC

Primary Biliary Cholangitis

Canada
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
University of Alberta

Completed

Online Wellness Intervention for Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

Canada
Zydus Therapeutics Inc.

Completed

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis (EPICS)

Primary Biliary Cirrhosis

United States
Cascade Pharmaceuticals, Inc

Completed

Study of [14C]CS0159 in China Healthy Subjects

Primary Biliary Cholangitis

China
Salarius Pharmaceuticals, LLC
National Pediatric Cancer Foundation

Active, not recruiting

Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Ewing Sarcoma | Myxoid Liposarcoma | Fibromyxoid Tumor | Sarcoma,Soft Tissue | Desmoplastic Small Round Cell Tumor | Angiomatoid Fibrous Histiocytoma | Extraskeletal Myxoid Chondrosarcoma | Clear Cell Sarcoma | Primary Pulmonary Myxoid Sarcoma | Myoepithelial Tumor | Sclerosing Epithelioid Fibrosarcoma

United States
GlaxoSmithKline

Available

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Pruritus
Hannover Medical School
German Research Foundation

Terminated

Biliary Interventions in Critically Ill Patients With Secondary Sclerosing Cholangitis (BISCIT) (BISCIT)

Secondary Sclerosing Cholangitis

Germany
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Study Group

Withdrawn

A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES-PBC)

Primary Biliary Cholangitis

United States
CymaBay Therapeutics, Inc.

Completed

RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Primary Biliary Cholangitis

United States, Spain, France, Korea, Republic of, Denmark, Australia, Italy, United Kingdom, Belgium, Canada, Russian Federation, Romania, Germany, Hungary, Mexico, Turkey, Argentina, Austria, Chile, Czechia, Greece, Israel, New Zealand and more
Yale University
American Liver Foundation

Suspended

Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cascade Pharmaceuticals, Inc

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS0159 in Chinese Healthy Subjects

Primary Biliary Cholangitis

China
Intercept Pharmaceuticals

Terminated

Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis (COBALT)

Liver Cirrhosis, Biliary

United States, Spain, Korea, Republic of, Australia, Finland, Israel, Lithuania, United Kingdom, Belgium, Netherlands, Estonia, Brazil, Italy, Serbia, Sweden, Argentina, Austria, Canada, Chile, Denmark, France, Germany, Hong Kong, Hun... and more
GlaxoSmithKline

Completed

Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls

Pruritus

United States
University of California, Davis
Mars, Inc.

Completed

Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines

Healthy

United States
Intercept Pharmaceuticals

Terminated

Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment

Liver Cirrhosis, Biliary

United States, Argentina, Spain, Belgium, Germany, Canada, Australia, Estonia, Brazil, Hungary, Italy, Lithuania
University of Alberta

Completed

Mind-body Wellness Intervention in Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

Canada
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Group

Completed

Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES PBC)

Primary Biliary Cholangitis

United States
CymaBay Therapeutics, Inc.

Completed

ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Primary Biliary Cholangitis

United States, Spain, United Kingdom, Israel, France, Korea, Republic of, Australia, Italy, Hungary, Germany, Romania, Belgium, Canada, Greece, New Zealand, Austria, Serbia, Russian Federation, Argentina, Mexico, Netherlands, Chile, Polan...
CymaBay Therapeutics, Inc.

Completed

Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Germany, United Kingdom, Canada
Kiminori Kimura, MD
Japan Agency for Medical Research and Development; Ohara Pharmaceutical Co....

Completed

Safety, Tolerability of OP-724 in Patients With Primary Biliary Cholangitis (Phase I)

Liver Cirrhosis, Biliary | Primary Biliary Cholangitis (PBC)

Japan
Calliditas Therapeutics AB

Completed

Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol.

Primary Biliary Cirrhosis

United States, Israel, Belgium, Germany, United Kingdom, Spain, Greece, Canada, Italy
Arena Pharmaceuticals

Terminated

Safety, Tolerability, and Efficacy of Etrasimod (APD334) in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Australia, New Zealand

Search clinical trials for: Primary sclerosing cholangitis

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