Search clinical trials for: Therapeutic Vaccine

Total 22002 results

Insight Therapeutics, LLC
Brown University; Sanofi Pasteur, a Sanofi Company; Case Western Reserve University

Active, not recruiting

Recombinant Influenza Vaccination in U.S. Nursing Homes

Influenza | Influenza, Human | Influenza -Like Illness

United States
Insight Therapeutics, LLC
Brown University; Case Western Reserve University; Seqirus

Completed

Adjuvanted Influenza Vaccination in U.S. Nursing Homes

Influenza | Influenza-like Illness

United States
Gary Archer Ph.D.
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme (ATTAC)

Malignant Neoplasms of Brain

United States
Jaime Leandro Foundation for Therapeutic Cancer...

Enrolling by invitation

Basket Trial of Neoantigen Synthetic Long Peptide Vaccines in Patients With Advanced Malignancy

Cancer | Solid Tumor

United States
OX2 Therapeutics

Active, not recruiting

Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma

Glioblastoma

United States
Stemirna Therapeutics

Active, not recruiting

mRNA Booster Vaccine(SW-BIC-213) Compared With Pfizer andSinopharm Against Emerging VOCs

Efficacy | Safety | Immunogenicity

Lao People's Democratic Republic
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

Pneumococcal Infections

United States, Puerto Rico, Thailand, Turkey
Pfizer

Completed

Immunogenicity and Safety Study of a Vaccine Against Lyme Borreliosis, in Healthy Adults Aged 18 to 65 Years. Randomized, Controlled, Observer-blind Phase 2 Study.

Lyme Borreliosis

United States, Germany, Belgium
Stemirna Therapeutics

Completed

A Phase I/II Clinical Trial in Healthy People Aged 18 Years and Above

COVID-19 Pandemic

Lao People's Democratic Republic
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT) (HELIOS)

Cytomegalovirus (CMV)-Positive Recipients | Allogeneic, Hematopoietic Cell Transplant (HCT)

Japan, Korea, Republic of, United States, Canada, Australia, Belgium, France, Germany, Spain, Sweden, Taiwan
Marker Therapeutics, Inc.

Terminated

Folate Receptor Alpha Peptide Vaccine With GM-CSF Versus GM-CSF Alone in Patients With Platinum Sensitive Ovarian Cancer

Ovarian Cancer | Platinum Sensitive Ovarian Cancer

United States
Ministry of Health, Spain
Sociedad Española de Neumología y Cirugía Torácica; American College of Chest...

Completed

Pulmonary Embolism as a Cause of COPD Exacerbations (SLICE)

Chronic Obstructive Pulmonary Disease | Pulmonary Embolism

Spain
Medicenna Therapeutics, Inc.

Completed

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Glioblastoma | Glioblastoma Multiforme | Grade IV Astrocytoma | Grade IV Glioma

United States
Cellid Co., Ltd.

Completed

Safety and Tolerability Evaluation Study of BVAC-C in Patients With HPV Type 16 or 18 Positive Cervical Cancer

Uterine Cervical Neoplasms

Korea, Republic of
Joshua Brody
Celldex Therapeutics

Completed

In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy

Low-Grade B-cell Lymphoma

United States
Merck Sharp & Dohme LLC

Completed

A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)

Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms

United States, Australia, Hong Kong, Korea, Republic of, New Zealand, Singapore, Taiwan
Talaris Therapeutics Inc.
Northwestern University

No longer available

Induction of Donor-Specific Tolerance in Recipients of Live Donor Stem Cell Infusion (Compassionate Use)

Renal Failure

United States
Nykode Therapeutics ASA
Theradex; Vaccibody AS

Completed

An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3)

High Grade Cervical Intraepithelial Neoplasia

Germany
Arcturus Therapeutics, Inc.

Terminated

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

Covid19 | Corona Virus Infection | SARS-CoV Infection

United States, Singapore
Archivel Farma S.L.
London School of Hygiene and Tropical Medicine

Terminated

Safety of RUTI® Vaccination in MDR-TB Patients

Tuberculosis, Multidrug Resistant

Ukraine
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Aelix Therapeutics

Completed

Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)

HIV-1 Infection

Spain
National Institute of Allergy and Infectious Diseases...

Completed

HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study

HIV Infections

United States, Puerto Rico
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, is Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Evaluate Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Vaccine in Healthy Seronegative Adults Aged 18-64

Covid19 Vaccine

Canada
Anne Margarita Dyrhol Riise
University of Oslo; Haukeland University Hospital; Statens Serum Institut

Completed

Therapeutic Vaccination and Immune Modulation - New Treatment Strategies for the MDR Tuberculosis Pandemic (TBCOX2)

Tuberculosis

Norway
Institut Pasteur

Completed

A Phase I Study of a Therapeutic Vaccine Candidate in Patients With Localized Breast Cancer at High-Risk of Relapse (MAGTRIVACSEIN)

Breast Neoplasms

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Stage IV Anal Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Neoplasm | Stage IV Penile Cancer AJCC v8 | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Stage IV Cervical Cancer AJCC v8 | Stage IVA Cervical Cancer AJCC v8 | Stage IVB Cervical Cancer AJCC v8 | Stage... and other conditions

United States
Bristol-Myers Squibb

Completed

An Investigational Immuno-Therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Participants With Solid Cancers That Are Advanced or Have Spread

Advanced Cancer

United States, Canada, Italy, Netherlands, Spain, Israel
Bursa Yüksek İhtisas Education and Research Hospital

Completed

Evaluation of Deltoid Exercises on Injection Site Pain After (BNT162b2) COVID - 19 Vaccination

Injection Site Reaction | Vaccines, Adverse Effects

Turkey
Transgene
Bristol-Myers Squibb

Completed

A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer Metastatic

Hungary, France, United States, Belgium
National Cancer Institute (NCI)

Terminated

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Colorectal Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center
AstraZeneca; Marker Therapeutics, Inc.

Completed

TPIV200/huFR-1 (A Multi-Epitope Anti-Folate Receptor Vaccine) Plus Anti-PD-L1 MEDI4736 (Durvalumab) in Patients With Platinum Resistant Ovarian Cancer

Ovarian Cancer

United States
Cedars-Sinai Medical Center

Completed

Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma

Glioma | Glioblastoma | Astrocytoma | Brain Tumor | Glioblastoma Multiforme

United States
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor

Advanced Malignant Solid Tumor

China
Zhejiang Provincial People's Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Completed

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Carcinoma

China
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of and Immune Response to HIV Vaccination Followed by Treatment Interruption in HIV Infected Patients

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Protein Sciences Corporation

Completed

Active Immunization of Asymptomatic, HIV-Infected Individuals With Recombinant GP160 HIV-1 Antigen: A Phase I/II Study of Immunogenicity and Toxicity

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

HIV Infections | Sexually Transmitted Diseases

United States, Puerto Rico, South Africa, Brazil
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Comparative Blinded Trial of Several HIV-1 Derived Immunogens in Infected Individuals With >= 500 CD4 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Safety, Tolerability and Immune Response to LC002, an Experimental Therapeutic Vaccine, in Adults Receiving HAART

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I/II Study of Delayed-Type Hypersensitivity (DTH) Reactions to Intradermal HIV Envelope Antigen

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Biocine

Completed

A Phase I Study to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Antigen in Children Born to HIV-Infected Mothers

HIV Infections | HIV Seronegativity

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC; Adult AIDS Clinical Trials Group

Completed

Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy

HIV Infections | Herpes Zoster

United States
National Institute of Allergy and Infectious Diseases...
Biocine

Completed

A Placebo-Controlled, Phase I, Pilot Clinical Trial to Evaluate the Safety and Immunogenicity of ENV 2-3, a Yeast-Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59 in Individuals With HIV Infection (Placebo Patients Receive MF59 Emulsion Only)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Glaxo Wellcome

Completed

A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; MicroGeneSys Inc (nka Protein Sciences Corporation)

Completed

A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Protein Sciences Corporation

Completed

A Phase I/II Dose Escalation Study of Intradermal gp160 to Evaluate Safety, Delayed Type Hypersensitivity (Skin Test) Responses and Immunogenicity in Asymptomatic HIV Seropositive Patients With More Than 400 CD4+ Cells

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Immuno-US

Completed

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and Women

HIV Infections

United States, Puerto Rico, Brazil
National Institute of Allergy and Infectious Diseases...

Completed

Safety of the Candidate Vaccine C4-V3 Alone or With Interleukin-12 (IL-12) in HIV-Infected Patients Receiving Effective Anti-HIV Drug Therapy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Effectiveness of Adding Either an HIV Vaccine, Interleukin-2, or Both to a Patient's Anti-HIV Drug Combination

HIV Infections

United States, Puerto Rico

Search clinical trials for: Therapeutic Vaccine

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