Search clinical trials for: cardiovascular safety

Total 101297 results

Kukje Pharma

Not yet recruiting

A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Korea, Republic of
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions (Mini-Bentall)

Aortic Dissection | Minimally Invasive Surgical Procedures | Aortic Root Aneurysm

China
Hanmi Pharmaceutical Company Limited

Not yet recruiting

A Study to Evaluate Efficacy and Safety of HGP2102 in Essential Hypertension Patients

Hypertension
Genoss Co., Ltd.

Recruiting

Safety and Effectiveness of GENOSS DES in Patients With Multivessel Coronary Artery Disease (GENOSS-MV)

Percutaneous Coronary Intervention | Multivessel Coronary Artery Disease

Korea, Republic of
Second Xiangya Hospital of Central South University

Recruiting

Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy (SAFECARE)

Hypertrophic Obstructive Cardiomyopathy | Stereotactic Body Radiotherapy

China
Edwards Lifesciences

Not yet recruiting

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Mitral Regurgitation | Mitral Valve Disease | Mitral Stenosis
Yongtao Sun

Not yet recruiting

Efficacy and Safety of Liposomal Bupivacaine in Thoracic Paravertebral Nerve Block

Postoperative Analgesia | Thoracic Paravertebral Block | Thoracoscopic Lobectomy

China
Boryung Pharmaceutical Co., Ltd

Recruiting

A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C

Essential Hypertension | Primary Hypercholesterolemia

Korea, Republic of
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety of Empliciti® (Elotuzumab) When Treating Patients With Multiple Myeloma in Taiwan

Relapsed or Refractory Multiple Myeloma

Taiwan
Shanghai Wallaby Medical Technologies Co.,Inc.
Phenox GmbH; Beijing Wallaby Medical Technologies Co.,Inc.

Recruiting

To Evaluate the Safety and Effectiveness of Flow Modulation Device for Intracranial Aneurysms

Intracranial Aneurysm

China
Shanghai Wallaby Medical Technologies Co.,Inc.
Phenox GmbH; Beijing Wallaby Medical Technologies Co.,Inc.

Recruiting

To Evaluate the Safety and Efficacy of Intracranial Stent Assisted Endovascular Treatment of Intracranial Aneurysms

Intracranial Aneurysm

China
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Glaukos Corporation

Recruiting

Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, United Kingdom, Spain, Germany, Australia, Canada, Puerto Rico, Bulgaria, Poland, Romania
Akura Medical

Recruiting

Safety and Effectiveness of the ATC System in the Treatment of Acute PE

Pulmonary Embolism Acute

Brazil, Dominican Republic
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Evaluate the Efficacy and Safety of Edoxaban on Prevention of Catheter-related Thrombosis (CRT) in Cancer Patients (Thrombosis)

Cancer | Catheter Complications | Thrombosis, Venous

China
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Chronic Kidney Disease

United States
Ever Supreme Bio Technology Co., Ltd.

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells as an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients

ST Elevation Myocardial Infarction

Taiwan
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

Korea, Republic of
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease

Behçet's Disease

China
Wuhan Union Hospital, China

Recruiting

Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma

Multiple Myeloma | Extramedullary Multiple Myeloma | Primary Plasma Cell Leukemia

China
Anterogen Co., Ltd.

Recruiting

A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-302 Clinical Trial

Diabetic Foot Ulcer

Korea, Republic of
Yi Yang

Not yet recruiting

Safety and Efficacy of Urinary Kallidinogenase for Large Artery Atherosclerosis Acute Ischemic Stroke

Acute Ischemic Stroke

China
Pan Xiangbin

Recruiting

A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Efficacy for the Treatment of Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

China
The First Affiliated Hospital of University of...

Not yet recruiting

Advancing Stroke Safety and Efficacy Through Early Tirofiban Administration After Intravenous Thrombolysis (ASSET-IT) (ASSET-IT)

Acute Ischemic Stroke

China
Xuzhou Medical University
Yake Biotechnology Ltd.

Recruiting

Safety and Efficacy of APRIL-BAFF-Bicephali CAR-T in Relapsed, Refractory Multiple Myeloma (CAR-T)

Multiple Myeloma

China
Novartis Pharmaceuticals

Recruiting

Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GCA or PMR

Giant Cell Arteritis | Polymyalgia Rheumatica

United States, Spain, Switzerland, Italy, Portugal
Liquidia Technologies, Inc.

Recruiting

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH (ASCENT)

Pulmonary Hypertension | Interstitial Lung Disease

United States
Bristol-Myers Squibb

Recruiting

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) (AURORA-HFpEF)

Heart Failure

United States, Spain, Canada, Italy, Poland
Chinese PLA General Hospital

Not yet recruiting

Safety and Efficacy Study of Implantable Neuromodulation for Poststroke Hemiplegia

Stroke | Hemiplegia | Stroke Sequelae | Deep Brain Stimulation | Vagus Nerve Stimulation | Motor Recovery

China
Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Canada
The Affiliated Hospital of Xuzhou Medical University
RainMed Medical

Recruiting

Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI Patients (FlashIV)

STEMI | Microvascular Coronary Artery Disease

China
Sirius Therapeutics Co., Ltd.

Recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants

Thrombosis

Australia
Jing Huang
The Second Affiliated Hospital of Chongqing Medical University

Not yet recruiting

The Safety and Efficacy of Carotid Body Modulation Therapy in Hypertensive Patients by External Ultrasonic Micro-bubble

Primary Hypertension

China
AceLink Therapeutics, Inc.
Tigermed Consulting Co., Ltd

Recruiting

Study of the Safety and Biologic Activity of AL01211 in Treatment Naive Males With Classic Fabry Disease

Fabry Disease

China
PT Bio Farma

Recruiting

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Safety Issues | Effect of Drug

Indonesia
Seoul National University Hospital

Recruiting

Safety and Efficacy of Paclitaxel Coated PTCA Balloon Catheter With a Shellac Plus Vitamin E Excipient (GENOSS® DCB) in Patients With Coronary In-stent Restenosis (ISR): A Prospective, Multi-center, Observational Study (SFRGENISTA)

Coronary Artery Disease | In-stent Restenosis

Korea, Republic of
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Beijing Tiantan Hospital

Recruiting

Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO) (ANGEL-BAO)

Acute Ischemic Stroke | Basilar Artery Occlusion

China
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR)

Aortic Regurgitation

China
Pacertool AS

Not yet recruiting

Pacertool Early Feasibility Study - Safety and Performance

Heart Failure With Reduced Ejection Fraction | Dyssynchrony | Medical Device Performance

Georgia
Cvaid Medical
Donawa Lifescience Consulting

Not yet recruiting

A Multi-center, Non-interventional Prospective Clinical Trial to Evaluate the Safety and Effectiveness of CVA-FLOW

Stroke

United States, Spain
Massachusetts General Hospital

Recruiting

Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF (POLARIS)

Atrial Fibrillation

United States
Endomatic Ltd.

Recruiting

Safety and Performance of ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device

Atrial Fibrillation

Georgia
Bilix Co.,Ltd.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants

Ischemia-reperfusion Injury

Australia
Novartis Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Coronary Heart Disease | Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Germany, Canada, United States
Newel Health SRL

Not yet recruiting

Assessment of Efficacy and Safety of Amicomed®, for the Management of Essential Hypertension

Essential Hypertension | Primary Hypertension
Starton Therapeutics, Inc

Recruiting

Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Lenalidomide in Multiple Myeloma (MM)

Multiple Myeloma

United States
Pfizer

Recruiting

A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India

Transthyretin Amyloid Cardiomyopathy

India
Genoss Co., Ltd.

Recruiting

Evaluation of Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENCOMX)

Coronary Artery Disease | Percutaneous Coronary Intervention

Korea, Republic of

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