Search clinical trials for: double-blind phase II study

Total 145723 results

Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women (MIVODON-II)

Infertility, Female | Oocyte Maturation

Spain
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Limited-stage Small Cell Lung Cancer (LS-SCLC)

China, France, United States, Spain, Taiwan, Korea, Republic of, Turkey, Italy, Netherlands, Georgia, Germany, Belgium, Poland, Romania
Akeso

Not yet recruiting

A Phase II Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

A Phase IB/II Clinical Study of SHR-A2009 for Injection in Combination With Other Antitumor Therapies in Patients With Advanced Solid Tumors

Advanced Solid Tumors
JCR Pharmaceuticals Co., Ltd.

Recruiting

Phase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIA

Mucopolysaccharidosis III-A

Germany
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Fudan University

Not yet recruiting

A Phase II Study of T-DXd Plus SRT in HER2-positive Breast Cancer Brain Metastases

Breast Cancer | Brain Metastases | Radiotherapy

China
University of Illinois at Chicago

Recruiting

BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer (BRE-08)

Breast Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)

Prostate Cancer

United States
Peking Union Medical College Hospital

Recruiting

Phase I/II Study of Linperlisib Plus Chidamide for R/R Peripheral T-cell Lymphoma: a Prospective, Multi-center Study

Peripheral T Cell Lymphoma

China
AstraZeneca

Recruiting

A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma (ATHENA)

Hepatocellular Carcinoma

United States, Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer

Recurrence | Thyroid Cancer

China
Sinotau Pharmaceutical Group

Recruiting

Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer

Prostate Cancer

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor (OPTISAGE)

GVHD
University of Texas Southwestern Medical Center

Recruiting

Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy (G-FORCE)

Laryngeal Carcinoma

United States
Vivacelle Bio

Not yet recruiting

A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02) (VBI-S-02)

Sepsis | Septic Shock | Hypovolemia
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
GERCOR - Multidisciplinary Oncology Cooperative...

Recruiting

Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study (DEWI)

Gastric Adenocarcinoma | Adenocarcinoma - GEJ

France
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Phase III Study of SHR-A1811 Injection With or Without Pertuzumab in HER2-Positive Recurrent or Metastatic Breast Cancer

HER2-PositiveRecurrent or Metastatic Breast Cancer
Centre Leon Berard

Recruiting

Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer (PRadR)

Metastatic Clear Cell Renal Cell Carcinoma

France
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Head and Neck Cancer

Taiwan, United States, Korea, Republic of, Spain, Belgium, Israel
Alentis Therapeutics AG

Recruiting

Study of ALE.C04 in Patients With Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States, Hong Kong, Singapore, Spain, Canada, Italy
National Cancer Institute (NCI)

Not yet recruiting

Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease

United States
Sinovac Life Sciences Co., Ltd.

Recruiting

SA55 Injection Phase II Study in the Treatment of Mild/Moderate COVID-19 Patients

Infection of Upper Respiratory Tract Caused by 2019-nCoV

China
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Follicular Lymphoma

United States
Peking Union Medical College Hospital

Recruiting

Phase I/II Study of Linperlisib Plus Chidamide for R/R Cutaneous T-cell Lymphoma: a Prospective, Single-center Study

Cutaneous T-cell Lymphoma

China
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Phase III Study of SY-5007, a RET Inhibitor, in Patients With Locally Advanced or Metastatic RET Fusion-positive NSCLC

Non-Small Cell Lung Cancer

China
Peking University First Hospital
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Recruiting

A Phase II Neoadjuvant Study of Darolutamide Plus ADT in Men With Localized Prostate Cancer

Prostate Cancer

China
Yonsei University

Recruiting

A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) (DOVE)

Uterine Cervical Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Vulvar Cancer | Clear Cell Carcinoma | Vagina Neoplasm

Korea, Republic of
Sun Yat-sen University

Recruiting

Efficacy of Modified Fruquintinib in Colorectal Cancer Liver Metastases: A Phase II Study

Colorectal Cancer Metastatic

China
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE

Lupus Erythematosus, Systemic

China
Samsung Medical Center

Not yet recruiting

An Open Label Phase II Study of First-Line Maintenance Enzalutamide Following Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Castration-Naive Prostatic Adenocarcinoma

Prostatic Adenocarcinoma

Korea, Republic of
AstraZeneca
Parexel

Not yet recruiting

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus (LAVENDER)

Cutaneous Lupus Erythematosus

United States, Belgium, Germany, Italy, Spain, France, Korea, Republic of, Philippines, United Kingdom, China, Austria, Australia, Netherlands, Bulgaria, South Africa, Taiwan, Denmark, Poland, Serbia, Argentina, Chile, Brazil, Colombia and more
Avistone Biotechnology Co., Ltd.

Recruiting

A Phase Ⅱ Study Assessing the Safety and Efficacy of PLB1004 in EGFR ex20ins Mutation Patients With Advanced and Metastatic Non-small Cell Lung Cancer(NSCLC) (Kannon)

Non-Small-Cell Lung Cancer

China
Empros Pharma AB
CTC Clinical Trial Consultants AB

Recruiting

A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers

Overweight or Obesity

Sweden
The First Affiliated Hospital with Nanjing Medical...
First Affiliated Hospital of Wenzhou Medical University

Recruiting

A Phase II Clinical Study of Treatment With Disitamb Vedotin Plus Pyrotinib in HER2-positive Early Breast Cancer

Breast Cancer

China
Sun Yat-sen University

Not yet recruiting

A Single Arm, Phase II Exploratory Clinical Study of Pemitinib in Advanced Gastric Cancer With Previous Standard Therapy Failure the FGFR Variant

Locally Advanced Unresectable Gastric Cancer

China
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

Phase I/II FIH Study of 9MW2921 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Skyline Therapeutics (US) Inc.

Recruiting

Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Neovascular Age-related Macular Degeneration

China, United States
Institut Paoli-Calmettes
Merck KGaA, Darmstadt, Germany; National Cancer Institute, France

Not yet recruiting

I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers (MATRIX)

Breast Cancer

France
Novartis Pharmaceuticals

Recruiting

A Phase I/II, Open-label, Multi-center Study of [225Ac]Ac-PSMA-R2 in Men With PSMA-positive Prostate Cancer With or Without Prior 177Lu-PSMA Radioligand Therapy.

Metastatic Castration-resistant Prostate Cancer (mCRPC)

France
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology

Gastric Adenocarcinoma | Carcinomatosis

United States
Zurich Regional Health Center

Recruiting

Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study

Neurologic Symptoms

Switzerland
Michael, Levy M.D.,Ph.D.
Jazz Pharmaceuticals

Not yet recruiting

A Phase IIb Study of Nabiximols for Spasticity Due to Neuromyelitis Optica Spectrum Disorders (SENS-NMO)

Spasticity, Muscle | NMO Spectrum Disorder

United States
Sohag University

Not yet recruiting

Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study

Post Operative Sore Throat
Zhejiang Cancer Hospital

Recruiting

Phase II Study of Fruquintinib Combined With Sintilimab and TACE for Inoperable Primary Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Fudan University

Not yet recruiting

Phase II Study of Sufantinib Combined With AG Versus AG First-line in the Treatment of LAPC or mPC

Pancreatic Neoplasms

China
Beijing Tide Pharmaceutical Co., Ltd

Recruiting

A Phase I/II Clinical Study in Patients With Advanced Solid Tumor.

Patients With Advanced Solid Tumors

China
Taiho Oncology, Inc.

Recruiting

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. (REZILIENT2)

Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

United States, Japan, Spain, France, Australia, Italy, Korea, Republic of, United Kingdom, Canada, Germany, Turkey, Hong Kong

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