Search clinical trials for: immune tolerance

Total 60020 results

Atlantia Food Clinical Trials
Caelus Pharmaceuticals BV

Completed

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

Glucose Metabolism Disorders | Metabolic Syndrome | Insulin Resistance | Impaired Glucose Tolerance | Insulin Sensitivity | Pre Diabetes

Ireland, United States, United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Tolerance and Pharmacokinetics of SHR1459 in Patients With Recurrent Replased/Refractory Mature B Cell Neoplasmstumor

Mature B Cell Neoplasms

China
ConvaTec Inc.
ClinSearch

Withdrawn

GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter Disorders (FollowAir)

Multiple Sclerosis | Parkinsonian Disorders | Spinal Cord Injuries | Allodynia
Katarzyna Siedzik

Completed

The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response

Glucose Metabolism Disorders | Body Weight | Insulin Resistance | Lipid Metabolism Disorders | Oxidative Stress | Insulin Sensitivity | Ketosis | Ketoses, Metabolic | Body Fat Disorder | Carbohydrate Metabolism Disorder | Somatic Disorders | Immunologic Factors | Trimethylamine N-oxide | Insulin Tolerance

Poland
Youngene Therapeutics Inc., Ltd.
ProSciento, Inc.

Completed

A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes

Diabetes Mellitus | Diabetes | Diabetes Mellitus, Type 1 | Type1diabetes

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

HIV Infections

United States, Puerto Rico, Thailand, Botswana, Argentina, Brazil, Tanzania, South Africa
Hasanuddin University
Arla Foods

Completed

The Tolerance of Organic Formula Milk and Its Fecal Microbiome Characteristic in Infants (TOFeM)

Food Allergy in Infants

Indonesia
University of Vermont Medical Center
National Dairy Council

Completed

Full-fat Yogurt and Glucose Tolerance

Pre-Diabetes

United States
Ogevity Therapeutics, Inc.
National University, Singapore

Completed

Immune Responses With Reduxium

Viral Infection | Immune Tolerance

Singapore
Takeda

Completed

Assessment of Immune Activation and Tolerance in Celiac Disease During Gluten Challenge

Celiac Disease

United States
University of Saskatchewan

Completed

Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild Asthma

Asthma

Canada
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Low Pressure Pneumoperitoneum and Deep Neuromuscular Block Versus Standard Laparoscopy During Robot Assisted Radical Prostatectomy to Improve the Quality of Recovery and Immune Homeostasis; Study Protocol for a Randomized Controlled Study. (RECOVER-2)

Quality of Life | Postoperative Complications | Acute Pain | Immune System Tolerance

Netherlands
Stanford University

Enrolling by invitation

Kidney and Hematopoietic Cell Transplants Using a Regimen to Promote Hematopoietic Cell Engraftment

Immune Tolerance

United States
Massachusetts General Hospital

Completed

Study of Pregnancy Regulation of Insulin and Glucose (SPRING)

Gestational Diabetes Mellitus

United States
GlaxoSmithKline

Completed

A Study to Assess the Local Cutaneous and Ocular Tolerance of Three Developmental Facial Skin-care Formulations.

Skin Care

Germany
Genzyme, a Sanofi Company

Terminated

Immune Tolerance Induction Study

Glycogen Storage Disease Type II (GSD-II) | Pompe Disease | Glycogenesis 2 Acid Maltase Deficiency

United States, Israel
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

Hemophilia A With Inhibitors

United States, Spain, Canada, Belgium, France, Bulgaria, Italy, United Kingdom, Japan, Germany
Diabeter Nederland BV
University Medical Center Groningen

Completed

Biomarkers of Heterogeneity in Type 1 Diabetes

Type 1 Diabetes

Netherlands
Sanofi

Terminated

Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia (ISLAY)

T-cell Type Acute Leukemia-Precursor | T-lymphoblastic Lymphoma/Leukaemia

Hungary, United States, Finland, France, Italy, Lithuania, Russian Federation
Swedish Orphan Biovitrum
Bioverativ Therapeutics Inc.

Completed

Study of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Failed Previous ITI Therapies (ReITIrate)

Hemophilia A

Ireland, United Kingdom, Germany, United States, Canada, Slovenia, Sweden
Hvidovre University Hospital
University of Copenhagen

Completed

Effect of RYGB on Alpha- and Beta Cell Function and Sensitivity to Incretins in Patients With Type 2 Diabetes (BETASIN)

Obesity, Morbid | Type2 Diabetes

Denmark
University of North Carolina, Chapel Hill
National Center for Complementary and Integrative Health (NCCIH); University... and other collaborators

Completed

FARE Peanut SLIT and Early Tolerance Induction (FARE/SLIT)

Food Hypersensitivity | Peanut Hypersensitivity | Peanut Allergy | Food Allergy

United States
University of Oulu
Business Finland

Completed

Home-based Exercise Training in Cardiac Patients (VAPA-Oulu)

Quality of Life | Physical Fitness | Autonomic Nervous System Imbalance | Patient Adherence

Finland
Pierre Fabre Dermo Cosmetique

Completed

IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Balm)

Hypersensitive | Reactive and Intolerant Skin | Redness-prone Skin | Stinger Subjects

China
University Hospital, Brest

Completed

Study of the Efficacy and Tolerance of Light Therapy in Sensitive Skin (SENSILED)

Sensitive Skin

France
Pierre Fabre Dermo Cosmetique

Completed

IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Cream)

Hypersensitive | Reactive and Intolerant Skin | Redness-prone Skin | Stinger Subjects

China
Santen SAS

Completed

Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)

Conjunctivitis, Vernal

France
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Terminated

Alphanate in Immune Tolerance Induction Therapy

Hemophilia A, Congenital

United States, Spain, Italy, India, Canada, Russian Federation
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB

HIV Infections | Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Dominque Bullens
Jessa Hospital; Imelda Hospital, Bonheiden; AZ Sint-Jan AV; Algemeen Ziekenhuis...

Active, not recruiting

Gradual Egg-tolerance Induction in Hen's Egg Allergic Children (TETI)

Egg Hypersensitivity

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

Escalating Multiple-Dose Safety and Tolerance of WR 6026 Hydrochloride in HIV-Infected Subjects

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Zidovudine Plus Acyclovir in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I Concentration-Controlled Trial to Assess the Safety, Tolerance, Pharmacokinetics and Development of Decreased HIV-1 Susceptibility to the Combination of Atevirdine Mesylate (U-87201E), Zidovudine (AZT), and Didanosine (ddI)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Trial of the Combination of Zidovudine and Recombinant Interleukin-2 in Patients With Persistent Generalized Lymphadenopathy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease

HIV Infections | Cytomegalovirus Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Pharmacokinetic and Tolerance Study of Ribavirin in Human Immunodeficiency Virus (HIV) - Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure

HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Tolerance of Indinavir Plus Ritonavir in HIV-Positive Patients Failing Therapy With Amprenavir, Nelfinavir, or Saquinavir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

HIV Infections | Bacterial Infections | Mycoses

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Evaluate the Safety and Tolerance of Stavudine (d4T) in Combination With Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Evaluate the Safety and Tolerance of Nelfinavir (NFV) Given With Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants

HIV Infections | Pregnancy

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants

HIV Infections | Pregnancy

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I, Dose-Escalating Safety and Tolerance Study of sCD4-PE40 in HIV-Infected Persons

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Biogen

Completed

An Escalating Dose Tolerance Trial of BG8962 (rCD4) in Patients Who Are HIV Antibody Positive

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected Women

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Phase III Study to Evaluate the Safety, Tolerance, and Efficacy of Early Treatment With Zidovudine (AZT) in Asymptomatic Infants With HIV Infection

HIV Infections

United States, Puerto Rico

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