Search clinical trials for: toxicity

Total 1659 results

Rigshospitalet, Denmark
Odense University Hospital; Aarhus University Hospital; Medical University of... and other collaborators

Recruiting

Severe Toxicity Free Survival Following Childhood Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

Denmark
Alexandria University

Not yet recruiting

The Efficacy of L-Carnitine in the Management of Acute Clozapine Intoxication

Clozapine Poisoning
SRI International

Recruiting

Study of Single Oral Doses of HOPO 14-1 Evaluating Safety, Tolerability, Pharmacokinetics

Toxicity;Chemical

United States
Tufts Medical Center

Recruiting

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Infection in Solid Organ Transplant Recipients | Antiviral Toxicity

United States
Taipei Medical University WanFang Hospital
Asia University

Recruiting

Oligo-Fucoidan Decrease Lung Radiation Damage (FIRILI)

Radiation Toxicity

Taiwan
University of Leeds

Not yet recruiting

Prostate Reirradiation Toxicity Outcomes Feasibility Study (RO-PIP)

Prostate Cancer | Radiotherapy Side Effect
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
Ankara University

Recruiting

Povidone Iodine Irrıgation at Hip-Knee Arthroplasty

Osteoarthritis | Hyperthyroidism | Iodine Toxicity

Turkey
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
Laval University

Recruiting

Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation (Oxygap pong)

Respiratory Failure | Oxygen Toxicity

Canada
University Hospital, Lille
Janssen Pharmaceutica N.V., Belgium

Not yet recruiting

Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma (IFM2021-01)

Multiple Myeloma
Namik Kemal University

Recruiting

CARG, VES13, G8 Scales in Predicting Drug Toxicity in Patients Receiving Nivolumab

Nivolumab Related Toxicity

Turkey
Rutgers, The State University of New Jersey

Recruiting

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Cardiac Toxicity | Early-stage Breast Cancer

United States
University of Rochester
Medical College of Wisconsin

Recruiting

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

Prostate Cancer | Radiation Toxicity | Urinary Complication

United States
Richard Dart, MD, PhD
Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division

Recruiting

Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose

Liver Failure | Drug Overdose | Acetaminophen Overdose | Acetaminophen | Drug-induced Liver Injury | Acetaminophen Poisoning | Liver Toxicity

United States
University Hospital, Caen

Recruiting

Pharmacogenetics of Liver Toxicity in Patients With Multiple Sclerosis Treated With Fingolimod

Multiple Sclerosis

France
University of Geneva, Switzerland
All India Institute of Medical Sciences, New Delhi; Swiss National Science... and other collaborators

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia (MPGx-INDALL)

Drug Effect | Pediatric Cancer | Adverse Drug Event | Drug Interaction | ALL, Childhood | Drug Toxicity | Toxicity, Drug | Relapse Leukemia

India
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Medical Checklists in the Emergency Department

Emergencies | Tricyclic Antidepressant Poisoning | Tricyclic Antidepressant Toxicity

Netherlands
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Acquired Immunodeficiency Syndrome
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Lymphoma, B-Cell | Hodgkin Lymphoma | Lymphoblastic Lymphoma | Lymphoma, T-Cell | AML | Hematologic Malignancy | MDS | Acute Undifferentiated Leukemia | ALL | Mixed Phenotype Acute Leukemia | BPDCN

United States, Australia
Jianxing He

Not yet recruiting

Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy

Cough | Drug Effect | Lung Cancer, Nonsmall Cell | Perioperative | Drug Toxicity
Laval University

Not yet recruiting

Activated CHARcoal in Poisoned Patient (CHARPP-RCT)

Charcoal, Decontamination, Poisoning
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer

Chemotherapy Effect | DNA Damage Repair Deficiency | Chemotherapeutic Toxicity | Hormone Sensitive Metastatic Prostate Cancer

China
Institut de cancérologie Strasbourg Europe

Recruiting

Efficacity of Deep Inspiration Breath Hold and Intensity-modulated Radiotherapy in Preventing PErfusion Defect for Left Sided Breast Cancer (EDIPE) (EDIPE)

Breast Cancer

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Predictive Markers of Response and Toxicity in Patients With a Haematological Malignancy Treated With Immunotherapy. (PRONOSTIM)

Blood Cancer

France
Assiut University

Not yet recruiting

Prediction of Chemotherapy Toxicity and Survival in Elderly Cancer Patients by CARG Score

Solid Tumors ,Adults
Centre Francois Baclesse, Luxembourg
BIONEXT; NEOLYS DIAGNOSTICS - ALARA GROUP

Not yet recruiting

Pre-therapeutic Analysis of the Individual Radiosensitivity of Cancer Patients in Luxembourg (APRI-Lux): Prospective National Interventional Study With Minimal Risk

Cancer | Radiation Toxicity | Radiosensitivity
Jules Bordet Institute

Recruiting

Immunological Variables Associated to ICI Toxicity in Cancer Patients

Melanoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma, Malignant | Bladder Cancer | Gastrointestinal Cancer | Merkel Cell Carcinoma | Non-melanoma Skin Cancer | MSI-H Colorectal Cancer

Belgium
The Hospital for Sick Children
Thalassemia Foundation of Canada

Recruiting

Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

Thalassemia in Children

Canada
Bernardino Clavo, MD, PhD
Servicio Canario de Salud; Red de Investigación en Servicios de Salud en Enfermedades... and other collaborators

Recruiting

Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025 (EPOOzo)

Chronic Pain | Radiation Toxicity | Chemotherapeutic Toxicity | Chemotherapy-induced Peripheral Neuropathy | Refractory Pain | Delayed Wound Healing

Spain
Belfast Health and Social Care Trust

Recruiting

Hyperoxia Induced Pulmonary Inflammation and Organ Injury: a Human in Vivo Model

Acute Lung Injury | Oxygen Toxicity | Pulmonary Injury

United Kingdom
University Hospital Hradec Kralove

Recruiting

The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

Brain Damage | Hydrocephalus | General Anesthetics Toxicity

Czechia
University of California, San Francisco

Recruiting

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

Respiratory Depression | Opioid Toxicity | Pupillary Miosis

United States
Medical College of Wisconsin
The Cleveland Clinic

Not yet recruiting

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

Ischemia | Coronary Artery Disease | Heart Failure | Hypertension | Diabetes Mellitus | Cardiomyopathies | Peripheral Artery Disease | Cardiotoxicity

United States
Assiut University

Not yet recruiting

Impact of N-acetylcysteine Infusion and Intralipid Infusion on Myocardial Injury in Aluminum Phosphide Toxicity

Myocardial Injury
Assiut University

Not yet recruiting

Cardiac Toxicity of Hypo Fractionated Radiotherapy in Left Breast Cancer

Breast Cancer Female
NHS Greater Glasgow and Clyde
Pneumowave Ltd

Recruiting

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED)

Respiratory Insufficiency | Overdose of Opiate | Sedative Overdose | Sedative Toxicity

United Kingdom
Anhui Provincial Hospital

Recruiting

Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma

Toxicity, Drug

China
Amsterdam UMC, location VUmc
Dutch Cancer Society

Recruiting

Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients (ABLATIVE-2)

Breast Cancer

Netherlands
Sun Yat-sen University

Recruiting

Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial

Nasopharyngeal Carcinoma

China
Uppsala University Hospital
Swedish Cancer Society; Lantmännen AB; Sjöbergstiftelsen; Onkologiska klinikens...

Recruiting

Role of Antisecretory Factor in Dihydropyrimidine Treatment of Colorectal Cancer (SALFLADMET)

Dihydropyrimidine Induced Gastrointestinal Toxicity in Colorectal Cancer

Sweden
Massimo Falconi

Recruiting

Financial Toxicity and Patient-Reported Outcomes in GEP-NEN During Treatment (FiReNEN)

Neuroendocrine Tumors

Italy
Guangxi Medical University

Not yet recruiting

Hearing Toxicity of Nasopharyngeal Carcinoma After Chemoradiotherapy

Nasopharyngeal Carcinoma
NHS Greater Glasgow and Clyde
Public Health Scotland

Recruiting

ASSIST: A Surveillance Study of Illicit Substance Toxicity (ASSIST)

Drug Effect | Drug Use | Drug Abuse | Drug Toxicity | Illicit Drug Use | Overdose, Drug | Illicit Drug Overdose | Illicit Drug Intoxication

United Kingdom
Central Hospital, Nancy, France
PAPE Elise

Not yet recruiting

Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis (DIFFUPERPED)

Appendicitis | Peritonitis | Children, Only | Antibiotic Toxicity
Memorial Sloan Kettering Cancer Center

Recruiting

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

HPV-Related Malignancy | Oropharynx Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | HPV

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

AC vs TC in Patients With HR-positive, HER2-negative Early Breast Cancer

Breast Cancer | Chemotherapeutic Toxicity

China
Medical College of Wisconsin

Recruiting

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis (REDIRICT)

Solid Tumor

United States
Fundación Pública Andaluza para la gestión de la...

Recruiting

Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material (DURATIOM)

Infections

Spain

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