Search clinical trials for: escalated dose

Total 20922 results

University of Oulu
Bayer; Kuopio University Hospital; Tampere University

Completed

Low-Dose Aspirin in in Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) Treatments

Pregnancy | Preeclampsia | Intrauterine Fetal Growth Restriction | Miscarriage Less Than 12 Gestational Weeks | Extrauterine Pregnancy

Finland
Medical University of Vienna
Polymun Scientific, Vienna, Austria

Completed

Recombinant Human Superoxide Dismutase (rhSOD) and Vascular Reactivity

Inflammation

Austria
Neosil, Inc.

Unknown

Dose-Ranging Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss

Androgenetic Alopecia

Germany
University of California, San Francisco

Completed

A Randomized Placebo-Controlled, Crossover-Design Study of the Effects of Low Dose Naltrexone

Multiple Sclerosis

United States
LungenClinic Grosshansdorf

Unknown

Erlotinib Versus Carboplatin/Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) (TIE)

Non-Small Cell Lung Cancer

Germany
Shiraz University of Medical Sciences

Completed

Low Doses of Cholestyramine in the Treatment of Hyperthyroidism

Graves Disease

Iran, Islamic Republic of
GlycaNova Norge AS
Centre for clinical studies, Bergen, Norway

Unknown

Dose Escalation Safety Study of MM-10-001 in Healthy Subjects

Healthy

Norway
Danish Breast Cancer Cooperative Group
Sanofi; Hoffmann-La Roche

Unknown

Vinorelbine Plus (+) Trastuzumab vs Docetaxel Plus (+) Trastuzumab as 1 Line Treatment for HER2 Positive (+) Metastatic Breast Cancer

Breast Cancer

Denmark
Institut de Recherche pour le Developpement
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand

HIV Infections | Pregnancy

Thailand
Netherlands Organisation for Scientific Research

Completed

Single Dose Versus Two Weeks Course of Fluconazole in the Treatment of Oropharyngeal Candidiasis in HIV Infected Individuals in Tanzania (SDVS2WK)

Oropharyngeal Candidiasis

Tanzania
Peregrine Pharmaceuticals

Completed

Repeat-Dose Study of Bavituximab in Patients With Chronic Hepatitis C

Hepatitis C

United States
Children's National Research Institute
Actelion

Completed

Pharmacokinetics, Safety and Tolerability of Zavesca (Miglustat) in Patients With Infantile Onset Gangliosidosis: Single and Steady State Oral Doses

Sandhoff Disease | GM2 Gangliosidoses | Tay-Sachs

United States
Montreal Heart Institute
Pfizer

Terminated

High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients

Hypertension

Canada
Hospital Universitari Son Dureta
Sociedad Española de Neumología y Cirugía Torácica; Fondo de Investigación...

Completed

Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) Exacerbations

COPD

Spain
University of Turku
Sanofi

Unknown

Biweekly Docetaxel in Combination With Capecitabine as First-Line Treatment in Patients With Advanced Gastric Cancer (GAST-TaxXel)

Stomach Neoplasms

Finland
Point Biomedical

Completed

Dose Finding Study of PB127 Ultrasound Contrast Agent in Healthy Volunteers and Patients With Coronary Artery Disease

Coronary Artery Disease | Healthy

United States
Novartis
Novartis Vaccines

Completed

Immunogenicity, Safety and Tolerability of Two Doses of FLUAD-H5N1 Influenza Vaccine in Adult and Elderly Subjects

Influenza

Poland
Cordis Corporation

Completed

Evaluation of Two Reduced Sirolimus Doses in Treatment of de Novo Coronary Artery Lesions (REDOX)

Coronary Artery Disease

Brazil
Sanofi

Completed

ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria

Malaria

Cameroon, Madagascar, Mali, Senegal
Sinovac Biotech Co., Ltd
Centers for Disease Control and Prevention, China

Completed

Safety and Immunogenicity of Booster Dose of An Inactivated,Adjuvanted Whole-Virion Pandemic Influenza(H5N1)Vaccine

Prevention | Pandemic Influenza | Pandemic Influenza Vaccine

China
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma

Asthma, Bronchial | Bronchial Asthma

Russian Federation, Hungary, Germany, Poland, Bulgaria, Ukraine, Czech Republic
Rigshospitalet, Denmark

Completed

Comparison of Acceleromyography (AMG) and Mechanomyography (MMG) for Establishing Potency of Neuromuscular Blocking Agents

Neuromuscular Blockade

Denmark
Tata Memorial Hospital

Unknown

Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Squamous Cell Carcinoma of the Head and Neck

India
Sheba Medical Center

Unknown

Pharmacogenetic Study of Warfarin Dose-Response: a Prospective Trial (PGxWarfarin)

Cardiovascular Diseases

Israel
Sao Jose do Rio Preto Medical School

Completed

Iron-Deficiency Anemia in Infants in Two Weekly Programs (IDA)

Anemia
University of Oxford

Completed

A Study of 2 Doses of a New TB Vaccine, MVA85A, in Healthy Volunteers Previously Vaccinated With BCG

Tuberculosis

United Kingdom
Par Pharmaceutical, Inc.
SFBC Ft. Myers, Inc

Completed

Bioavailability Study of Tranylcypromine 10mg Tablets Under Fasting Conditions

To Determine the Bioavailability of Tranylcypromine

United States
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Completed

Bioavailability Study of Leflunomide Tablets Under Fasting Conditions

To Determine the Bioequivalence Study Under Fasting
Critical Therapeutics

Terminated

Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS

Asthma

United States
University of California, San Francisco
Sandler Family Supporting Foundation

Completed

Effect of an Inhaled Corticosteroid on Airway Gene Expression in Asthma

Asthma

United States
Abbott

Completed

Assessment of the Effect of Adalimumab on Response to Influenza Virus and Pneumococcal Vaccines in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Assistance Publique - Hôpitaux de Paris
French Health Products Safety Agency

Completed

Adjustment of DOses of NIcotine in Smoking Cessation (ADONIS) (ADONIS)

Smoking Cessation

France
Solvay Pharmaceuticals

Completed

A Multinational, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Investigate the Efficacy, Safety and Duration of Effect of a Single Administration of Various Doses of Cetrorelix SR in Subjects With Histologically Confirmed Endometriosis

Endometriosis

Russian Federation, Australia, Belgium, Bulgaria, Germany, Romania, South Africa, Ukraine
University Hospital, Ghent

Completed

Does Low-Dose Aspirin Improve Outcome in In Vitro Fertilisation/Intra Cytoplasmatic Sperm Injection (IVF/ICSI)?

Infertility

Belgium
University of Toronto
Multiple Sclerosis Society of Canada; Direct MS-Proactive Charity

Completed

Safety Trial of High Dose Oral Vitamin D3 With Calcium in Multiple Sclerosis (VitD4MS)

Multiple Sclerosis

Canada
University of Aarhus
The Swedish Research Council for Environment, Agricultural Sciences and Spatial... and other collaborators

Completed

Dose Response Relations for Health Effects Caused by Office Dust

Discomfort Symptoms | Changed Lung Function

Denmark
Gilead Sciences

Completed

Open Label Study of Pharmacokinetics and Safety of Dose of Adefovir Dipivoxil in Children and Adolescents With HBV

Hepatitis B

Belgium, Germany, Poland, United Kingdom
University of Michigan Rogel Cancer Center

Terminated

Companion Pharmacogenetic Study to UMCC 9900/9901

Metastatic Breast Cancer

United States
Shen-Zhen City Maternity and Child Healthcare Hospital

Completed

Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose

Polycystic Ovary Syndrome | Infertility | Anovulation
Newron Pharmaceuticals SPA

Completed

Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist

Idiopathic Parkinson's Disease
Weill Medical College of Cornell University
Pfizer

Completed

An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus)

Diabetic Neuropathy

United States
Newron Pharmaceuticals SPA

Completed

Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist (12 Month Extension)

Parkinson's Disease
STEBA France
STEBA LABORATORIES LTD.

Completed

Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers

Gastroesophageal Reflux | Esophagitis | Duodenal Ulcer | Stomach Ulcer

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria (DESY)

Nephrolithiasis | Dent's Disease

France
PAION Deutschland GmbH

Completed

Dose Escalation of Desmoteplase in Acute Ischemic Stroke (DEDAS) (DEDAS)

Stroke
University of Copenhagen

Completed

Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults

Cardiovascular Disease | Constipation

Denmark
Deutsches Herzzentrum Muenchen

Completed

International PRospective Multicenter Study On RadiaTion Dose Estimates Of Coronary CT AngIOgraphy IN Daily Practice (PROTECTION-I)

Coronary Disease

Germany
AZ-VUB
Sanofi

Unknown

Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Carcinoma

Belgium
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously

Arrhythmia

United States
Azevan Pharmaceuticals

Completed

Multiple Dose Safety Study of SRX251 Capsules in Healthy Volunteers

Healthy

United States

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