Search clinical trials for: Dose reduction

Total 25105 results

University of Aarhus
The Swedish Research Council for Environment, Agricultural Sciences and Spatial... and other collaborators

Completed

Dose Response Relations for Health Effects Caused by Office Dust

Discomfort Symptoms | Changed Lung Function

Denmark
Gilead Sciences

Completed

Open Label Study of Pharmacokinetics and Safety of Dose of Adefovir Dipivoxil in Children and Adolescents With HBV

Hepatitis B

Belgium, Germany, Poland, United Kingdom
University of Michigan Rogel Cancer Center

Terminated

Companion Pharmacogenetic Study to UMCC 9900/9901

Metastatic Breast Cancer

United States
Shen-Zhen City Maternity and Child Healthcare Hospital

Completed

Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose

Polycystic Ovary Syndrome | Infertility | Anovulation
Newron Pharmaceuticals SPA

Completed

Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist

Idiopathic Parkinson's Disease
Weill Medical College of Cornell University
Pfizer

Completed

An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus)

Diabetic Neuropathy

United States
Newron Pharmaceuticals SPA

Completed

Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist (12 Month Extension)

Parkinson's Disease
STEBA France
STEBA LABORATORIES LTD.

Completed

Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers

Gastroesophageal Reflux | Esophagitis | Duodenal Ulcer | Stomach Ulcer

United States
AstraZeneca

Completed

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/12.5 and 32/25 mg in Comparison With Candesartan 32 mg

Hypertension

United Kingdom, Germany, Sweden, Estonia, Lithuania, Poland, Ukraine, Denmark, Netherlands, France, Former Serbia and Montenegro
Assistance Publique - Hôpitaux de Paris

Terminated

Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria (DESY)

Nephrolithiasis | Dent's Disease

France
PAION Deutschland GmbH

Completed

Dose Escalation of Desmoteplase in Acute Ischemic Stroke (DEDAS) (DEDAS)

Stroke
University of Copenhagen

Completed

Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults

Cardiovascular Disease | Constipation

Denmark
USGI Medical

Completed

Endoscopic Stomach and Pouch Reduction in Patients With Weight Regain Following Roux-En-Y Bypass Surgery

Obesity

United States
Deutsches Herzzentrum Muenchen

Completed

International PRospective Multicenter Study On RadiaTion Dose Estimates Of Coronary CT AngIOgraphy IN Daily Practice (PROTECTION-I)

Coronary Disease

Germany
AZ-VUB
Sanofi

Unknown

Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Carcinoma

Belgium
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously

Arrhythmia

United States
Azevan Pharmaceuticals

Completed

Multiple Dose Safety Study of SRX251 Capsules in Healthy Volunteers

Healthy

United States
Tel-Aviv Sourasky Medical Center

Unknown

Low-Dose Risperidone Treatment for Subjects Suffering From Borderline Personality Disorder

Borderlone Personality Disorder

Israel
National Center for Complementary and Integrative...

Completed

Meditation-Based Stress Reduction in Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Weill Medical College of Cornell University
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety Study of Low Dose Interleukin 2 (IL-2) Plus PEG-IFN/RBV In Chronic Hepatitis C Virus Genotype I

Hepatitis C

United States
Aeris Therapeutics

Terminated

Israeli 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation

Pulmonary Emphysema

Israel
Aeris Therapeutics

Completed

US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study

Pulmonary Emphysema

United States
NeurogesX

Completed

NGX-4010 for the Treatment of Postherpetic Neuralgia

Pain | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Shingles

United States
NeurogesX

Completed

Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy

HIV Infections | Pain | Peripheral Nervous System Diseases

United States
NeurogesX

Terminated

Study of NGX-4010 for Treatment of Painful HIV-Associated Neuropathy

HIV Infections | Pain | Peripheral Nervous System Diseases

United States
Aeris Therapeutics

Completed

US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation

Pulmonary Emphysema

United States
NeurogesX

Completed

Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia

Pain | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster

United States
National Cancer Institute (NCI)

Completed

Antimetabolite Induction, High-Dose Alkylating Agent Consolidation and Retroviral Transduction of the MDR1 Gene Into Peripheral Blood Progenitor Cells Followed by Intensification Therapy With Sequential Paclitaxel and Doxorubicin for Stage 4 Breast Cancer

Breast Neoplasms | Neoplasm Metastasis

United States
National Institutes of Health Clinical Center (CC)

Completed

The Early Reversibility of Rocuronium After Different Doses of Neostigmine

Paralysis

United States
National Institute of Mental Health (NIMH)

Completed

Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112

Healthy

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency

Healthy | Cushing's Syndrome | Adrenal Gland Hyperfunction | Adrenal Gland Hypofunction

United States
National Institute of Neurological Disorders and...

Completed

Intravenous Immunoglobulin (IVIg) for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Demyelinating Diseases | Paraproteinemias

United States
Charite University, Berlin, Germany
Techniker Krankenkasse

Completed

Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents (GERSHWIN)

Coronary Artery Disease

Germany
National Cancer Institute (NCI)

Completed

Phase I Study of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Escalating Dose I.P. Platinum for Gastrointestinal Peritoneal Carcinomatosis

Stomach Neoplasms | Peritoneal Neoplasms

United States
National Cancer Institute (NCI)

Completed

New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastoma

Neuroblastoma | Rhabdomyosarcoma | Ewing's Sarcoma

United States
National Institute of Neurological Disorders and...

Completed

Treatment of Parkinson's Disease With a Transdermal Skin Patch

Parkinson Disease

United States
National Cancer Institute (NCI)

Completed

A Pilot Study to Investigate the Clinical Utility of the Peregrine Monte Carlo Dose Calculation System for Radiation Therapy Treatment Planning

Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver

Neoplasm Metastasis | Liver Neoplasms

United States
National Institute of Neurological Disorders and...

Completed

Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity

Healthy

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver

Neoplasm Metastasis | Colorectal Neoplasm | Liver Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of AC (Adriamycin, Cyclophosphamide) Chemotherapy With G-CSF (Granulocyte Colony-Stimulating Factor) Followed by Infusional Taxol (Paclitaxel) as Adjuvant Treatment for High Risk Stage II and Stage III Breast Cancer Patients

Breast Cancer | Breast Neoplasms

United States
National Cancer Institute (NCI)

Completed

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

Brain Neoplasms | Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Treatment of Patients With Cancer With Genetically Modified Salmonella Typhimurium Bacteria

Cancer | Neoplasm Metastasis | Neoplasm

United States
National Institute of Neurological Disorders and...

Completed

Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory Myopathies

Dermatomyositis | Polymyositis | Inclusion Body Myositis

United States
National Institute of Neurological Disorders and...

Completed

High-Dose Intravenous Immunoglobulin to Treat Cerebellar Degeneration

Spinocerebellar Degenerations

United States
National Cancer Institute (NCI)

Completed

Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma

Lymphoma | Testicular Neoplasms | Breast Neoplasms | Neoplasm Metastasis

United States
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
National Institute of Dental and Craniofacial Research...

Completed

Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction

Pain

United States
National Cancer Institute (NCI)

Completed

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

Neoplasm Metastasis | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2

Gastrointestinal Diseases | Candidiasis, Oral | Stomatitis

United States

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