Clinical Trials Sponsored by Exact Sciences Corporation

Total 595 results

McMaster University
Hamilton Health Sciences Corporation

Completed

Remote Ischemic Preconditioning in Cardiac Surgery Trial (Remote IMPACT)

Cardiac Surgery

Canada, United States
Hamilton Health Sciences Corporation
McMaster University

Completed

Post-Operative Impact of Nasogastric Tubes on Rates of Emesis in Infants Diagnosed With Pyloric Stenosis (POINTS)

Pyloric Stenosis

Canada
Hamilton Health Sciences Corporation

Unknown

Study of a Tiotropium Inhaler For Shortness of Breath in Advanced Non-Small Cell Lung Cancer (TIDAL)

NSCLC | Dyspnea

Canada
Hamilton Health Sciences Corporation
McMaster University

Withdrawn

Ultrasound Guided Diagnostic Lumbar Medial Branch Blocks

Back Pain

Canada
McMaster University
Hamilton Health Sciences Corporation

Completed

Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment

Post Operative Pain | Total Knee Replacement

Canada
Hamilton Health Sciences Corporation

Withdrawn

Biochemical Approach to Measuring Surgical Trauma

Total Knee Replacement

Canada
Hamilton Health Sciences Corporation

Completed

Angiotensin Converting Enzyme Inhibitors & Contrast Induced Nephropathy in Patients Receiving a Cardiac Catheterization

Kidney Failure

Canada
McMaster University
Hamilton Health Sciences Corporation

Unknown

A Pilot Study of ALTENS in Improving Dysphagia Induced by IMRT for Head and Neck Cancers

Head and Neck Cancer | Dysphagia

Canada
Hamilton Health Sciences Corporation

Completed

Comparing Point of Care Clotting Tests in the OR Versus Standard Laboratory Clotting Tests

Coronary Artery Bypass Grafting

Canada
Hamilton Health Sciences Corporation

Completed

The Effects Of Methacholine Challenge Administered Using Three Different Nebulizers On Small Airways Function

Asthma

Canada
Hamilton Health Sciences Corporation

Completed

Targeting Inflammation in Acute Coronary Syndrome Using Colchicine (COOL)

Acute Coronary Syndrome

Canada
Hamilton Health Sciences Corporation

Unknown

Functional Behavioural Skill Training for Young Children With Severe Autism

Autistic Disorder

Canada
Hamilton Health Sciences Corporation

Completed

Luteal Phase Administration of Paroxetine for the Treatment of PMDD (PMDD)

Premenstrual Dysphoric Disorder

Canada
Hamilton Health Sciences Corporation

Unknown

Pentastarch Use in Cardiac Surgery

Cardiac Surgery | Cardiopulmonary Bypass

Canada
Hamilton Health Sciences Corporation

Completed

Older Adult Training Study With Creatine and CLA (OTR)

Sarcopenia

Canada
Hamilton Health Sciences Corporation

Unknown

Two Approaches to Providing HIV/AIDS Services in the Community to People Living With HIV/AIDS

HIV Infection

Canada
McGill University
Posit Science Corporation

Completed

Cognitive Training for the Remediation of Functional Brain Health in HIV

Cognitive Impairment | HIV - Human Immunodeficiency Virus

Canada
Nuralogix Corporation
University Health Network, Toronto; Hamilton Health Sciences Corporation

Not yet recruiting

Peri-operative Mobile Application for Contactless Screening and Vital Signs Measurement (MAC-VITAL)

Vital Signs

Canada
Orion Corporation, Orion Pharma
PRA Health Sciences

Terminated

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of ODM-108: in Healthy Male Volunteers (FIMTRIP)

Healthy

Netherlands
Hamilton Health Sciences Corporation
Sunovion

Completed

Evaluation of the Effect of Levalbuterol on Allergen Induced Airway Inflammation In Subjects With Atopic Asthma

Asthma
Hamilton Health Sciences Corporation
Abbott

Terminated

State of Obesity Care in Canada Evaluation Registry

Obesity | Morbid Obesity

Canada
Wake Forest University Health Sciences
Omeros Corporation

Completed

No Drop Post-Op Cataract Surgery

Cataract

United States
McMaster University
Pfizer; Hamilton Health Sciences Corporation

Completed

A Study of Pregabalin (Lyrica) Augmentation in Serotonin Reuptake Inhibitor-Refractory Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder

Canada
Hamilton Health Sciences Corporation
AstraZeneca

Completed

Does Fluticasone Propionate Reduce the Late Allergic Reaction When the Drug is Given Post-allergen?

Mild Intermittent Asthma

Canada
McMaster Children's Hospital
Hamilton Health Sciences Corporation

Completed

Photographic Email Correspondence for Pediatric Urology Post-Operative Patients

Post-Operative Complication | Pediatric Urology

Canada
Hamilton Health Sciences Corporation
GlaxoSmithKline

Unknown

Fondaparinux to Prevent Thrombotic Complications and Graft Failure in Patients Undergoing Coronary Artery Bypass Graft Surgery: The Fonda CABG Study (Fonda CABG)

Coronary Bypass Graft Failure/Occlusion

Canada
Posit Science Corporation
University of Minnesota

Completed

Care Improving Cognition for ADolescents on the Autism Spectrum (CICADAS)

Autism Spectrum Disorder

United States
Vinh Hoan Corporation
KGK Science Inc.

Completed

Efficacy of Vinh Wellness Collagen on Skin Health

Skin Manifestations | Skin Abnormalities

Canada
Posit Science Corporation
University of Iowa

Completed

Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease (PACR-AD)

Older Adults, Aging Brain

United States
Hamilton Health Sciences Corporation
Pfizer

Terminated

Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders

Obsessive-Compulsive Disorder | Anxiety Disorders | Phobia, Social | Major Depressive Disorder | Panic Disorder | Agoraphobia

Canada
Alison Fox-Robichaud

Completed

Studies of Blood DNA in Patients With Severe Infection DYNAMICS (DYNAMICS)

Sepsis | Shock | Trauma

Canada
McMaster University
Pfizer; Hamilton Health Sciences Corporation

Terminated

Pregabalin Versus Placebo as an Add on for Complex Regional Pain Syndrome (CPRS) of the Upper Limb Managed by Stellate Ganglion Block (The PREGA Study) (PREGA)

Complex Regional Pain Syndromes

Canada
Hamilton Health Sciences Corporation
Actelion

Unknown

A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Hypertension, Pulmonary | Connective Tissue Disease

Canada
Hamilton Health Sciences Corporation
AstraZeneca

Completed

Cognition, Functioning and Quality of Life

Schizophrenia

Canada
Hamilton Health Sciences Corporation
Tehran University of Medical Sciences; Tohoku University

Recruiting

Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting

Functional Dyspepsia | Peptic Ulcer | Gastro Esophageal Reflux | Normal Control

Canada, Iran, Islamic Republic of, Japan
Hamilton Health Sciences Corporation
Sunnybrook Health Sciences Centre; Medtronic

Completed

Second Canadian Trial of Physiologic Pacing (CTOPP II): Pilot Trial

Pacemaker Dependence

Canada
Hamilton Health Sciences Corporation
One Fertility

Not yet recruiting

Supplementation for Male Subfertility (FertEnhancer)

Male Infertility

Canada
Hamilton Health Sciences Corporation
Juravinski Cancer Centre Foundation

Not yet recruiting

Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma (IGNITE-V)

Vulvar Cancer
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology-3 Trial (PVC-RAM-3)

Surgery

Canada
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery (ASPIRE-AF)

Stroke | Atrial Fibrillation

Canada, Australia, Germany, Denmark, Switzerland, Spain, Korea, Republic of, New Zealand, Argentina, India, Netherlands, United Kingdom, Brazil, Italy, Nepal, Sweden, Pakistan
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Low INR to Minimize Bleeding With Mechanical Valves Trial (LIMIT)

Bleeding Post-mechanical Valve Replacement | Thromboembolism Post-mechanical Valve Replacement

Canada, Spain, Belgium, Russian Federation, Netherlands, Brazil
Population Health Research Institute
Hamilton Health Sciences Corporation

Completed

Ross for Valve Replacement in AduLts Trial (REVIVAL)

Aortic Valve Disease

Canada
Mohawk College
Hamilton Health Sciences Corporation; Ryerson University

Completed

Detection of Motor Seizures Using WBAN (DMS-WBAN)

Seizures, Tonic-Clonic

Canada
McMaster University
GlaxoSmithKline; Novartis; Hamilton Health Sciences Corporation

Completed

A Trial of Eltrombopag or Intravenous Immune Globulin Before Surgery for Immune Thrombocytopenia Patients

Immune Thrombocytopenic Purpura

Canada, Netherlands
Population Health Research Institute
Hamilton Health Sciences Corporation

Completed

Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial)

Type 2 Diabetes Mellitus

Canada
Hamilton Health Sciences Corporation
Population Health Research Institute

Terminated

Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy (BAV Study) (BAV)

Cardiac Disease

Canada
Hamilton Health Sciences Corporation
Population Health Research Institute

Unknown

Apixaban Dose Reduction in Patients With Elevated Drug Levels (ADREL)

Atrial Fibrillation

Canada
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Surgical Ablation of AF Efficacy Trial (SAFE)

Heart Failure | Atrial Fibrillation

Canada
Wake Forest University Health Sciences
Boston Scientific Corporation

Recruiting

Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy (SASS)

Stress Urinary Incontinence | Pelvic Floor Disorders

United States, South Africa
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial (DANCE)

Bleeding Post Cardiac Surgery | Indication for Anticoagulation

Canada

Clinical Trials Sponsored by Exact Sciences Corporation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cameroon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations