Clinical Trials Sponsored by Institute of Cancer Research, United Kingdom

Total 3530 results

University College, London
National Institute for Health Research, United Kingdom

Completed

Feasibility Study of Physiotherapy for Functional Motor Symptoms

Conversion Disorder

United Kingdom
University of Nottingham
National Institute for Health Research, United Kingdom; Arthritis Research UK

Completed

Effects of Internet / Web-based Exercises on the Population With Knee Arthritis (Knee OA)

Knee Osteoarthritis | Sleep Disturbance | Knee Pain Chronic

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers (HoT)

Differentiated Thyroid Cancer

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial (NAMinG)

Glaucoma, Open-Angle

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Recruiting

Passive Evaluation in Operational Environment of the AI Clinician Decision Support System for Sepsis Treatment

Sepsis

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia) (CiproPAL)

Acute Lymphoblastic Leukaemia - Category

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

Lymphatic Mapping Of Oropharyngeal Cancer (LOOC)

Oropharyngeal Cancer

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Recruiting

Who Will Benefit From Bariatric Surgery for Diabetes?

Obesity | Diabetes Mellitus, Type 2

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients (PITSTOP)

Head and Neck Fibrosis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

IMAGINATOR 2.0: Co-design and Early Evaluation of a Novel Blended Digital Intervention Targeting Self-harm in Young People (IMAG2)

Mental Health Disorder | Child Behavior Problem | Self Injurious Behavior | Adolescent Behavior Problem

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

RxConnect User Testing Study

Behavior

United Kingdom
Queen's University, Belfast
National Institute for Health Research, United Kingdom

Completed

Stroke Prevention Rehabilitation Intervention Trial of Exercise (SPRITE) (SPRITE)

Cerebrovascular Disorders

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)

ASTHMA | CHRONIC OBSTRUCTIVE PULMONARY DISEASE | HEALTHY SUBJECTS

United Kingdom
Valneva Austria GmbH
National Institute for Health Research, United Kingdom

Completed

Dose Finding Study to Evaluate The Safety, Tolerability and Immunogenicity of an Inactiviated, Adjuvanted SARS-CoV-2 Virus Vaccine Candidate Against Covid-19 in Healthy Subjects

SARS-CoV-2 Virus Infection

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Lipoprotein Apheresis in Refractory Angina Study

Refractory Angina | Raised Lipoprotein(a)>50mg/dL or >500mg/L

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Terminated

Bariatric Surgery and Guided Self-help for Binge Eating Disorder (BED)

Obesity

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Completed

Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Early Breast Cancer (TARGIT)

Breast Cancer | Invasive Breast Cancer

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Recruiting

Imperial Prostate 6 - Cancer Histology Artificial Intelligence Reliability Study. (IP6-CHAIROS)

Prostatic Neoplasms

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

Children's Acute Surgical Abdomen Programme (CASAP)

Surgery | Children, Only | Abdomen, Acute | Perioperative Complication

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Active, not recruiting

Primary Antibiotic Prophylaxis Using Co-trimoxazole to Prevent Spontaneous Bacterial Peritonitis in Cirrhosis (ASEPTIC)

Spontaneous Bacterial Peritonitis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Preschool Wheeze: Inflammation/Infection Guided Management (PrIGMa)

Asthma

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Active, not recruiting

Total Ankle Replacement Versus Arthrodesis Trial (TARVA)

Osteoarthritis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

AARDVARK (Aortic Aneurysmal Regression of Dilation: Value of ACE-Inhibition on RisK) (AARDVARK)

Abdominal Aortic Aneurysm

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Completed

The EXPLORE Study - The Use of Binocular OCT Imaging for the Assessment of Ocular Disease

Eye Diseases | Eye Infections | Eye Inflammation

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Unknown

A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer. (TARGIT-B)

Early Breast Cancer

France, Korea, Republic of, United Kingdom, Italy, United States, China, Malaysia, Saudi Arabia, South Africa, Spain, Switzerland, Thailand
University College, London
National Institute for Health Research, United Kingdom

Unknown

Paediatric Peri-operative Anxiety: Does the Little Journey App Help? (Little Journey)

Surgery | Psychological Distress | Children, Only | Anxiety Acute | Anxiety Fear | Peri-operative
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Splinting to Treat Hand Osteoarthritis (SPLINTOA)

Hand Osteoarthritis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

PPrime: Parents Views on Diagnosis and Information-giving in Neonatal Care (Pilot Study) (PPrime)

Parents of Preterm Infants Born Before 33 Weeks Gestation

United Kingdom
University Hospitals, Leicester
National Institute for Health Research, United Kingdom

Completed

A Diabetes Prevention Study Targeting High Risk Individuals With Education and Ongoing Support (PREVENTION)

Type 2 Diabetes Mellitus

United Kingdom
Royal Marsden NHS Foundation Trust
Wellcome Trust; Institute of Cancer Research, United Kingdom; Biomedical Research...

Completed

A Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)in Patients With Solid Tumours (PanRAF)

Melanoma | Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Sanofi; Janssen, LP; Menarini Group; University of Twente; Prostate Cancer UK

Terminated

Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer (CTC-STOP)

Adenocarcinoma of the Prostate

United Kingdom
University Hospital Southampton NHS Foundation...
Bristol-Myers Squibb; Cancer Research UK; Institute of Cancer Research, United...

Completed

The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer (ICE)

Extensive Stage Small Cell Lung Cancer

United Kingdom
European Organisation for Research and Treatment...
Institute of Cancer Research, United Kingdom; Arbeitsgruppe Lebermetastasen...

Terminated

Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

Netherlands, United Kingdom, Belgium, France, Germany, Sweden, Hungary, Austria, Egypt, Italy
Queen Mary University of London
National Institute for Health Research, United Kingdom

Completed

Achieving Control of Asthma in Children In Africa (ACACIA)

Asthma

Ghana, Malawi, Nigeria, South Africa, Uganda, Zimbabwe
Heart of England NHS Trust
National Institute for Health Research, United Kingdom

Unknown

Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD (E-CHECKED)

Cognitive Impairment

United Kingdom
University of Bath
National Institute for Health Research, United Kingdom; Earswitch Ltd.

Not yet recruiting

Technical Evaluation of Earswitch Phase B

Motor Neuron Disease
St George's, University of London
National Institute for Health Research, United Kingdom

Recruiting

Understanding Blood Pressure Changes After Birth

Hypertension in Pregnancy

United Kingdom
University of Nottingham
National Institute for Health Research, United Kingdom; Boots UK

Completed

The Experiences of People Prescribed Opioid Pain Medicines

Pain | Opioid Use

United Kingdom
University of Bath
National Institute for Health Research, United Kingdom; Earswitch Ltd.

Not yet recruiting

Technical Evaluation of Earswitch Phase A (Earswitch)

Motor Neuron Disease
University of York
National Institute for Health Research, United Kingdom; Keele University

Not yet recruiting

A Prognostic Model to PREDICT Relapse of Depression in Primary Care (PREDICTR)

Depression
Hazel Everitt
National Institute for Health Research, United Kingdom

Completed

Management of Irritable Bowel Syndrome in Primary Care (MIBS Trial) (MIBS)

Irritable Bowel Syndrome

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; Verastem, Inc.; Chugai Pharmaceutical

Recruiting

Phase I Trial of VS-6766 Alone and in Combination With Everolimus (RAF/MEK)

Multiple Myeloma | Ovarian Cancer | Lung Cancer | Solid Tumours

United Kingdom
Hoffmann-La Roche
Institute of Cancer Research, United Kingdom; German Low Grade Lymphoma Study...

Completed

A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM)

Non-Hodgkin's Lymphoma

Italy, Belgium, Canada, United Kingdom, Australia, China, Germany, United States, Russian Federation, Spain, Taiwan, Israel, Czechia, Hungary, Japan, France, Finland, Sweden
University of the West of England
National Institute for Health Research, United Kingdom

Not yet recruiting

Feasibility Study of ABC for Women Treated for Breast Cancer

Breast Cancer Female

United Kingdom
University of Oxford
National Institute for Health Research, United Kingdom; University of Dundee

Completed

A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 Years (I2S2)

Transient Hypothyroxinemia

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; Institute of Cancer Research, United Kingdom

Terminated

PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck (PEACH)

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma

United Kingdom
Royal Marsden NHS Foundation Trust
Pfizer; Roche Pharma AG; Institute of Cancer Research, United Kingdom

Unknown

PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib (PIPA)

Breast Cancer | Advanced Solid Tumours

United Kingdom
University of Exeter
University of Leeds; National Institute for Health Research, United Kingdom

Completed

Exploring 'VOLITION' in Context - a Study to Inform the Implementation of a New Intervention (VOLITION)

Aged | Multimorbidity | Decision Making | General Practice

United Kingdom
NSABP Foundation Inc
Royal Marsden NHS Foundation Trust; Pfizer; Institute of Cancer Research, United...

Completed

A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer (PALLET)

Breast Cancer | Breast Tumors | Breast Carcinoma

United Kingdom, United States, Canada

Clinical Trials Sponsored by Institute of Cancer Research, United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Austria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations