Clinical Trials Sponsored by Leiden University Medical Center

Total 13613 results

Noordwest Ziekenhuisgroep
Leiden University Medical Center

Not yet recruiting

MR Pulmonary Angiography to Replace CT Pulmonary Angiography for Patients With a Suspicion of a Pulmonary Embolism (MIRACLE)

Pulmonary Embolism | Radiation Exposure
Leiden University Medical Center
Medtronic - MITG

Recruiting

Leiden Trial In Prevention of Post-Operative ThromboEmbolic Events (TIPOTEE)

Deep-Venous Thrombosis

Netherlands
Spaarne Gasthuis
Leiden University Medical Center

Active, not recruiting

ALknee Follow-up Study of the Cementless ATTUNE Rotating Platform and the Cementless LCS Rotating Platform Knee System

Knee Osteoarthritis | Total Knee Arthroplasty | Total Knee Replacement

Netherlands
Leiden University Medical Center
Zimmer Biomet

Completed

Persona Versus NexGen

Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis Arthritis

Netherlands
Universiteit Antwerpen
Leiden University Medical Center

Unknown

Standardization of Lead Placement for Sacral Neuromodulation. Part 1

Overactive Bladder | Non Obstructive Urinary Retention

Belgium
Leiden University Medical Center
Trombosestichting Nederland

Completed

Advanced Diagnostic Management of Suspected Recurrent Ipsilateral DVT With MRDTI (Theia)

Deep Vein Thrombosis

Netherlands, Sweden, Canada, Israel, Norway
Leiden University Medical Center
Stryker Nordic

Terminated

Fluoroscopic and RSA Evaluation of the Triathlon Total Knee Prosthetic Design

Aseptic Loosening | Complications; Arthroplasty, Mechanical

Netherlands
Leiden University Medical Center
Novartis Pharmaceuticals

Unknown

Treatment Of Radiation Retinopathy Trial (TORR)

Uveal Melanoma
Leiden University Medical Center
Medical Center Haaglanden; Voeding Leeft

Active, not recruiting

The Effect of a Multimodal Lifestyle Intervention on Chronic Fatigue in Patients With Inflammatory Bowel Disease (Multi-IBD)

Fatigue | Inflammatory Bowel Diseases

Netherlands
The Netherlands Cancer Institute
Leiden University Medical Center; University Medical Center Nijmegen

Recruiting

Sarcomas and DDR-Inhibition; a Combined Modality Study (SADDRIN-1)

Soft Tissue Sarcoma Adult

Netherlands
Leiden University Medical Center
Comprehensive Cancer Centre The Netherlands; Dutch Cancer Society

Active, not recruiting

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer (PORTEC-4a)

Endometrial Cancer Stage I | Endometrial Cancer Stage II

Netherlands, Germany, Belgium, France, Austria, Czechia, Ireland, Switzerland
Leiden University Medical Center
Medical Center Haaglanden; DePuy International

Completed

RSA RCT: ATTUNE™ TKA Versus PFC Sigma TKA (APKnee)

Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis Arthritis

Netherlands
Leiden University Medical Center
UMC Utrecht; Erasmus Medical Center; Leiden University; Netherlands Institute of...

Completed

West Nile Virus Seroprevalence Under Bird Ringers

West Nile Virus

Netherlands
Medical University of Warsaw
Erasmus Medical Center; Leiden University Medical Center

Recruiting

Study of Virus-specific Lymphocytic Cell Populations in Non-invasive Nasal Mucosa Samples of MIS-C Patients

COVID-19 | MIS-C Associated With COVID-19

Poland
Franciscus Gasthuis
Maastricht University Medical Center; Leiden University Medical Center

Recruiting

Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates. (PROTEA)

Premature | Wheezing | LRTI

Netherlands
Medical Center Alkmaar
University of Amsterdam; Leiden University Medical Center

Unknown

Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD)

Inflammation | Chronic Obstructive Pulmonary Disease | Pulmonary Emphysema

Netherlands
University of Turku
Leiden University Medical Center

Completed

The Effect of Right Ventricular Pacing on Myocardial Oxidative Metabolism and Efficiency

Bradycardia

Finland
Sanaria Inc.
Radboud University Medical Center; Leiden University Medical Center

Completed

Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers

Malaria

Netherlands
University of Zurich
Leiden University Medical Center

Active, not recruiting

Metastases of Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients. The "SCOPE-ITSCC Metastases Study"

Squamous Cell Carcinoma

Netherlands, Switzerland
University Hospital, Ghent
Leiden University Medical Center

Completed

Assessment of Surgical sTaging vs Endoscopic Ultrasound in Lung Cancer: a Randomized Clinical Trial (ASTER Study)

Carcinoma, Non-Small-Cell Lung

Belgium, Netherlands, United Kingdom
Leiden University Medical Center
HollandPTC; Varian Medical Systems

Recruiting

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas (CHIPT)

Magnetic Resonance Imaging | Chondrosarcoma | Chordoma | Proton Therapy | Bone Neoplasm of Vertebral Column | PET-CT

Netherlands
Leiden University Medical Center
University of Tasmania

Terminated

Comparison of Oxygen Controllers in Preterm InfanTs (COCkPIT)

Hypoxia | Respiratory Insufficiency | Hyperoxia | Premature Infant

Netherlands
University Medical Center Groningen
Radboud University Medical Center; Erasmus Medical Center; Leiden University...

Unknown

Study of Lanreotide to Treat Polycystic Kidney Disease (DIPAK1)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Netherlands
Steno Diabetes Center Copenhagen
Leiden University Medical Center

Terminated

Bone Marrow Derived Allogeneic Mesenchymal Stromal Cells to Non-healing Diabetic Foot Wounds (REDDSTAR)

Diabetic Foot Ulcer

Denmark
Radboud University Medical Center
University Medical Center Groningen; Erasmus Medical Center; Leiden University...

Withdrawn

Pharmacokinetics of Single-dose Dolutegravir in HIV-seronegative Subjects With Severe Hepatic Impairment Compared to Matched Controls. (POLO)

Hepatic Impairment | HIV-1-infection
Leiden University
Dutch Cancer Society; ISA Pharmaceuticals; Top Institute Pharma

Completed

Hespecta Vaccination in HPV+ Tumors or Malignant Lesions

Tumors or Premalignant Lesions

Netherlands
Leiden University Medical Center
Trombosestichting Nederland; ISTH

Recruiting

Optimizing Diagnosis of Splanchic Vein Thrombosis With MRDTI (Rhea)

Splanchnic Vein Thrombosis

Netherlands, Italy
Natasha Appelman-Dijkstra

Recruiting

DEnosumab for the Treatment of FIbrous Dysplasia/McCune-Albright Syndrome in Adults (DeFiD) (DeFiD)

Fibrous Dysplasia | McCune Albright Syndrome

Netherlands
Leiden University Medical Center
Pierre Fabre Laboratories

Recruiting

(Neo)Adjuvant BRAF/MEK Inhibition in pN1c Melanoma

Melanoma Stage III | In-Transit Metastasis of Cutaneous Melanoma

Netherlands
EJAVerheijen
Spaarne Gasthuis

Recruiting

Prediction of TEI Success in Sciatica (POTEISS)

Lumbar Disc Herniation | Lumbar Spinal Stenosis | Lumbar Radiculopathy

Netherlands
Leiden University Medical Center
Aurinia Pharmaceuticals Inc.

Unknown

Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant Recipients (VOCOVID)

Covid19 | Kidney Transplant Infection

Netherlands
Serge A. Trines

Completed

Cerebral Embolism (CE) in Catheter Ablation of Atrial Fibrillation (AF) (CE-AF)

Atrial Fibrillation

Netherlands
Groene Hart Ziekenhuis
Leiden University Medical Center

Completed

Tourniquet Study: A Clinical Trial Into the Effect of Tourniquet Use on the Coagulation System

Venous Thrombosis

Netherlands
Unilever R&D
Leiden University Medical Center

Completed

Functional Magnetic Resonance Imaging of Human Hypothalamic Responses to Oral Temperature and Glucose Sensing (COLD)

Healthy

Netherlands
Maruho Co., Ltd.
Leiden University Medical Center

Completed

Pharmacodynamics, Safety and Efficacy of Topical Omiganan in Patients With External Genital Warts

Condylomata Acuminata (External)

Netherlands
Leiden University Medical Center
Netherlands Heart Foundation

Completed

Rosuvastatin Use to Improve the Coagulation Profile in Patients With Venous Thrombosis (START)

Deep Vein Thrombosis | Pulmonary Embolism

Netherlands
Örebro University, Sweden
Maastricht University Medical Center; Leiden University Medical Center

Recruiting

CBT Group Treatment for Women With Dyspareunia

Dyspareunia

Netherlands, Sweden
Peter den Hollander
Leiden University Medical Center

Recruiting

RSA-RCT: Attune S+ TKA Versus Sigma TKA (APKnee2-S+)

Rheumatic Diseases | Musculoskeletal Disease | Joint Disease | Osteoarthritis Arthritis

Netherlands
Unilever R&D
Leiden University Medical Center

Completed

fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose

Healthy

Netherlands
Ingrid Jazet
AstraZeneca

Unknown

Exenatide and Brown Adipose Tissue (exe01)

Obesity

Netherlands
Leiden University Medical Center
Netherlands Heart Foundation

Completed

Aspirin in Reduction of Tension II Study (ASPIRETENSION)

Cardiovascular Diseases | Hypertension

Netherlands
Leiden University Medical Center
Andaluz Health Service

Completed

"POWER2DM Evaluation Campaign" (POWER2DMEC)

Diabetes Mellitus | Health Behavior | Self Efficacy | Type2 Diabetes Mellitus | Type1 Diabetes Mellitus

Netherlands, Spain
Unilever R&D
Leiden University Medical Center

Completed

fMRI of Hypothalamic Responses to Taste, Temperature and Glucose (COLD-2)

Healthy

Netherlands
Unilever R&D
Leiden University Medical Center

Completed

RS-fMRI to Nutrient Shakes

Pleasure

Netherlands
Leiden University Medical Center
Medasense Biometrics Ltd

Completed

The Medasense Study

Pain

Netherlands
The Netherlands Cancer Institute
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Not yet recruiting

Upfront Resection of Locally Advanced NSCLC Followed by Chemoradiotherapy (UPLAN-I)

Feasibility | Surgery | Safety | Chemoradiotherapy | Locally Advanced Non-Small Cell Lung Cancer | Cavitation Lung
Leiden University Medical Center
Rivierduinen, Centre for Personality disorders Jelgersma

Completed

Cost- Effectiveness Study of Brief Interventions for Mood and Anxiety Disorders (K&K)

Depressive Disorder | Anxiety Disorder

Netherlands
Leiden University Medical Center
Erasmus Medical Center; The Netherlands Cancer Institute; Medical Center Haaglanden and other collaborators

Unknown

Identifying Novel Variants in the DPYD Gene in Patients of Non-Western Descent (DPYD-NOW)

Neoplasms
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; The Netherlands Cancer Institute; Leiden University...

Recruiting

NKI Therapy Compared to Usual Care of Recurrent Esophagogastric Anastomotic Strictures (SAMURAI)

Esophageal Stricture | Anastomotic Stenosis | Dilation of Esophagus Due to Disease

Netherlands
Johannes Gutenberg University Mainz
Leiden University Medical Center

Recruiting

Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life (SERENITY)

Terminal Cancer

Germany, Netherlands, United Kingdom, Spain, Denmark, France, Italy, Poland

Clinical Trials Sponsored by Leiden University Medical Center

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