Clinical Trials Sponsored by NextCure, Inc.

Total 35721 results

Seagen Inc.
Millennium Pharmaceuticals, Inc.

No longer available

A Treatment-Option Protocol to Provide Brentuximab Vedotin to Eligible Patients Completing Studies SGN35-005 or C25001

Lymphoma, Non-Hodgkin | Lymphoma, T-Cell, Cutaneous | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin

United States, United Kingdom, Belgium, Serbia, Australia, Bulgaria, France, Germany, Hungary, Italy, Poland, Romania, Russian Federation, Spain, Switzerland
EndoCeutics Inc.
AMAG Pharmaceuticals, Inc.

Withdrawn

Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study

Hypoactive Sexual Desire Disorder (HSDD)

United States
Eisai Korea Inc.

Completed

Halaven Post-Marketing Surveillance (PMS)

Breast Cancer

Korea, Republic of
Astellas Pharma Inc
Seagen Inc.

Completed

A Study of Enfortumab Vedotin in Japanese Subjects With Locally Advanced or Metastatic Urothelial Carcinoma

Metastatic Urothelial Cancer

Japan
Eisai Korea Inc.

Completed

Trial Evaluating the Efficacy and Safety of Perampanel Added to Monotherapy in Participants With Partial Onset Seizures With or Without Secondary Generalization

Epilepsy

Korea, Republic of
Illumina, Inc.
Agility Clinical, Inc.

Completed

A Study Collecting Blood Samples From Pregnant Women to Aid in the Development of a Noninvasive Prenatal Test

Pregnancy

United States
UpTru Inc.
Medicor Research Inc.

Completed

The Study of Oral Fluorescite to Confirm the Authenticity of Point of Care Urine Samples

Urine Sample Authenticity

Canada
Ocular Therapeutix, Inc.
ORA, Inc.

Completed

OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis

Chronic Allergic Conjunctivitis
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment

Cancer | Solid Tumor | Hepatic Impairment

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Effect of Tivantinib on the QTC Interval in Cancer Subjects

Solid Tumors

United States
Eisai Korea Inc.

Completed

A Study to Investigate the Efficacy and Safety of Eribulin in Korean Breast Cancer Participants

Locally Advanced or Metastatic Breast Cancer

Korea, Republic of
Cascadian Therapeutics Inc.

Completed

A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants

Healthy

United States
Cascadian Therapeutics Inc.

Completed

Study of the Pharmacokinetics and Pharmacodynamics of Crystalline PX-866 Tablets and Amorphous PX-866 Capsules in Healthy Volunteers

Healthy Volunteer

United States
Cascadian Therapeutics Inc.

Completed

Phase 1b Maintenance Therapy Study of ONT-10 in Patients With Solid Tumors

Solid Tumors

United States
Cascadian Therapeutics Inc.

Completed

Study of PX-866 and Docetaxel in Solid Tumors

Non Small Cell Lung Cancer (NSCLC) | Squamous Cell Carcinoma of the Head and Neck (SCCHN)

United States, Canada
KGK Science Inc.
ChromaDex, Inc.

Completed

A Study Investigating the Effects of Niagen™ in Healthy Adults. (15NRHC)

Bioavailability

Canada
Nicox Ophthalmics, Inc.
ORA, Inc.

Completed

A Multi-Center, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety of AC-170 Ophthalmic Solution

Healthy Subjects

United States
Agensys, Inc.

Completed

A Study of AGS-1C4D4 in Pancreatic Cancer Subjects Previously Treated in Protocol 2008002

Pancreatic Cancer | Pancreatic Disease | Carcinoma, Pancreatic Ductal

United States, Canada
Eisai Korea Inc.

Completed

Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease (SAVE)

Alzheimer's Disease

Korea, Republic of
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Completed

A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer

Breast Neoplasms | Prostatic Neoplasms | Ovarian Neoplasms

United States
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

Clinical Pharmacology Study of Brentuximab Vedotin (SGN-35)

Neoplasms | Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin | Carcinomas

United States
KGK Science Inc.
ChromaDex, Inc.

Completed

A Study of the Pharmacokinetics of Three Dosages of Niagen in Healthy Subjects (14NBHC)

Pharmacokinetics

Canada
Astellas Pharma Inc
Seagen Inc.

Completed

A Study to Determine the Maximum Tolerated Dose of ASG-5ME in Subjects With Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States
Catheter Robotics, Inc.
Medpace, Inc.

Completed

Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies

Ventricular Tachycardia | Atrial Flutter

United States, United Kingdom
Astellas Pharma Inc
Agensys, Inc.

Completed

A Phase 1 Study of the Safety and Pharmacokinetics of AGS-8M4 in Subjects With Advanced Ovarian Cancer

Carcinoma | Ovarian Diseases | Ovarian Neoplasms | Ovarian Cancer

United States
Esanex Inc.
Pfizer; Serenex, Inc.

Completed

Safety And Pharmacology Study Of SNX-5422 Mesylate In Subjects With Refractory Solid Tumor Malignancies

Cancer

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic Cancer

Secondary Malignant Neoplasm of Pancreas
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Accelerated Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
All India Institute of Medical Sciences, New Delhi
University of Michigan; NephCure Accelerating Cures Institute; Department of...

Completed

Prednisolone Trial in Children Younger Than 4 Years

Nephrotic Syndrome

India, United States
HeartBeam, Inc.
Meditrial USA Inc.

Not yet recruiting

AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection (VALID-ECG)

Atrial Fibrillation | Arrhythmias, Cardiac | Bradycardia | Tachycardia | Atrial Flutter

United States
GB002, Inc.

Recruiting

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Pulmonary Arterial Hypertension

United States, Spain, Israel, Korea, Republic of, Netherlands, France, Singapore, United Kingdom, Lithuania, Australia, Latvia, Argentina, Portugal, Greece, Czechia, Puerto Rico, Belgium, Italy, Poland, Romania, Serbia, Austria, Chile, Denma... and more
Combangio, Inc
Kala Pharmaceuticals, Inc.

Recruiting

Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED (CHASE)

Persistent Corneal Epithelial Defect

United States
Vivani Medical, Inc
Medpace, Inc.

Not yet recruiting

Assessment of Safety, Tolerability and Drug Levels of NPM-119 in Participants With Type 2 Diabetes (LIBERATE-1)

Type 2 Diabetes
Verastem, Inc.
Mirati Therapeutics Inc.

Recruiting

Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients (RAMP204)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung | Malignant Neoplastic Disease | KRAS Activating Mutation

United States
Criterium, Inc.
Novartis; Seagen Inc.

Recruiting

Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.

HER2-positive Metastatic Breast Cancer

United States
HBI Solutions Inc.
mProbe Inc.

Not yet recruiting

Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test

NAFLD | NASH - Nonalcoholic Steatohepatitis
Neovasc Inc.
Shockwave Medical, Inc.

Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II (COSIRA-II)

Refractory Angina

United States, Canada
Cofactor Genomics, Inc.
Curebase Inc.

Recruiting

A Multicenter Cancer Biospecimen Collection Study

Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Cancer of Head and Neck | Lung Cancer, Nonsmall Cell | Gastroesophageal Junction Adenocarcinoma

United States
AVM Biotechnology Inc
Medpace, Inc.

Not yet recruiting

Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS (AVM0703)

Covid19 | Influenza, Human | ARDS
Edgewise Therapeutics, Inc.
Medpace, Inc.

Completed

A Study of EDG-5506 in Adult Males With Becker Muscular Dystrophy (ARCH)

Becker Muscular Dystrophy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Pioglitazone HCl Tablets 45 mg and Actos® Tablets 45 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Doxycycline Monohydrate Tablets 150 mg and Adoxa Tablets 150 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Cetirizine HCl Tablets 10 mg and Zyrtec® Tablets 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Finasteride Tablets 5 mg and Proscar Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Rabeprazole Sodium Delayed-Release Tablets 20 mg to Aciphex® Tablets 20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Anagrelide Hydrochloride Capsules 1 mg to Agrylin® Capsules 1 mg

Healthy

United States

Clinical Trials Sponsored by NextCure, Inc.

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