Clinical Trials Sponsored by Otsuka Pharmaceutical Co., Ltd

Total 3871 results

Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Primary Open-angle Glaucoma

United States
Colorado Prevention Center
Otsuka Pharmaceutical Co., Ltd.

Completed

Evaluation of Cilostazol in Combination With L-Carnitine (ECLECTIC)

Peripheral Arterial Disease | Intermittent Claudication | Peripheral Vascular Disease

United States
Inje University
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Effect of Cilostazol in the Acute Lacunar Infarction Based on Pulsatility Index of Transcranial Doppler (ECLIPse)

Cerebral Infarction

Korea, Republic of
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride (SEATTLE)

Geographic Atrophy

United States
Lundbeck Canada Inc.
Otsuka Pharmaceutical Co., Ltd.

Terminated

Real Life Assessment of Abilify Maintena (ReLiAM)

Schizophrenia

Canada
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome

Dry Eye Syndrome

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy

Geographic Atrophy | Dry Age-related Macular Degeneration

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea

Dry Eye | Keratoconjunctivitis Sicca

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Patients With Dry Eye

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Tolerability of Repeat Doses of ACU-4429 in Healthy Subjects

Healthy

United States
Yonsei University
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Synergistic Effect of Combination Therapy With Cilostazol and Probucol on Plaque Stabilization and Lesion Regression: Serial Intravascular Ultrasound and Virtual Histology Study(SECURE Study)

Therapy

Korea, Republic of
Otsuka Pharmaceutical Europe Ltd

Completed

Predictors of Persistence in Patients With Schizophrenia Treated With Once-monthly Aripiprazole in Spain (PROSIGO)

Schizophrenia

Spain
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain (ALGA)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Spain
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy (ASSERT)

Cancer | Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Italy
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Otsuka Pharmaceutical Europe Ltd

Completed

Demographic and Clinical Predictors of Persistence in Patients Treated With Aripiprazole Once-monthly in Italy (DOMINO)

Schizophrenia

Italy
Otsuka Pharmaceutical Europe Ltd

Unknown

A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe (ACQUIRE)

Autosomal Dominant Polycystic Kidney Disease

Spain, United Kingdom, Germany, France, Belgium, Switzerland, Austria
Otsuka Pharmaceutical Europe Ltd

Completed

Adacolumn in Refractory UC Patients Trial (ART)

Ulcerative Colitis, Active Moderate

France
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Terminated

Efficacy and Safety of Brexpiprazole as Adjunctive Treatment in Elderly Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Major Depressive Disorder

United States
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With an Acetylcholinesterase Inhibitor (STARBRIGHT)

Alzheimer's Disease

United States, Australia, Brazil, Czechia, Germany, Israel, Korea, Republic of, Mexico, Serbia, Singapore, Slovakia, Spain, Switzerland, Turkey, United Kingdom
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Major Depressive Disorder

Finland, Sweden, Estonia, Bulgaria, United States, Canada, Germany, Korea, Republic of, Latvia, Lithuania, Mexico, Poland, Romania, Russian Federation, Ukraine, United Kingdom
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects

Alcohol Dependence

Japan
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole in Patients With Schizophrenia

Schizophrenia

Serbia, Estonia, United States, Poland, Romania, Russian Federation, Slovakia, Ukraine
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole in Patients With Acute Schizophrenia

Schizophrenia

United States
Seoul National Hospital
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

Effect on Metabolic Parameters of Abilify in SPR

Schizophrenia | Metabolic Syndrome

Korea, Republic of
Brigham and Women's Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

The Role of Vasopressin Antagonism on Renal Sodium Handling

Healthy
Japan Cardiovascular Research Foundation
Otsuka Pharmaceutical Co., Ltd.

Completed

Cilostazol Stroke Prevention Study for Antiplatelet Combination (CSPS・com)

Noncardioembolic Cerebral Infarction

Japan
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Terminated

Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder

Major Depressive Disorder

United States
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With Donepezil (STARSHINE)

Alzheimer's Disease

Germany, United States, Argentina, Belgium, Bulgaria, Canada, Chile, Czechia, Denmark, France, Italy, Poland, Romania, South Africa, Spain, Ukraine
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Aripiprazole Once-monthly Versus Paliperidone Palmitate in Adult Patients With Schizophrenia

Schizophrenia

United States
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Terminated

Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)

PTSD | Post-traumatic Stress Disorder

Finland, Estonia, South Africa, Poland, United States, France, Italy, Serbia, Sweden
Asan Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study (PICASSO-IMT)

Brain Ischemia | Intracranial Hemorrhages
Asan Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Overcome Biochemical Aspirin Resistance Through Cilostazol Combination (ARCC)

Cerebral Infarction

Korea, Republic of
Seoul National Hospital
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

Prevalence of the Metabolic Syndrome in SPR Taking Antipsychotics

Schizophrenia | Metabolic Syndrome

Korea, Republic of
Chonbuk National University Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

Effectiveness of Aripiprazole Long-acting Injection in Recent Onset and Chronic Schizophrenia Patients

Schizophrenia

Korea, Republic of
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)

Alcohol Dependence

Japan
Seoul National University Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder

Major Depressive Disorder

Korea, Republic of
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil (STARBEAM)

Alzheimer's Disease

United States, Argentina, Brazil, Canada, Croatia, Czechia, Estonia, Finland, France, Hungary, Israel, Italy, Korea, Republic of, Lithuania, Poland, Portugal, Taiwan, United Kingdom, Ireland
National University Hospital, Singapore
Otsuka Pharmaceutical Co., Ltd.

Unknown

Phase IIa Dose-Expansion and Biomarker Study of OPB-111077

NPC | Refractory Tumor

Singapore
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Aripiprazole Once-monthly in Patients With Schizophrenia

Schizophrenia

United States
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Withdrawn

Comparison of the Effectiveness of Brexpiprazole With That of Risperidone (TAILWIND)

Schizophrenia
YongChan Lee
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis (REPAIR)

Gastroesophageal Reflux

Korea, Republic of, China
Asan Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage (PICASSO)

Brain Ischemia | Intracranial Hemorrhages

Korea, Republic of, Philippines, China
M.D. Anderson Cancer Center
Otsuka Pharmaceutical Co., Ltd.

Terminated

Study to Assess OPB-31121 in Advanced Leukemias or Myelodysplastic Syndromes

Leukemia

United States
Lawson Health Research Institute
Otsuka Pharmaceutical Co., Ltd.

Completed

The Effects of Cranberry Juice on Bacterial Adhesion

Bacterial Vaginosis | Oxaluria
Kissei Pharmaceutical Co., Ltd.
JCR Pharmaceuticals Co., Ltd.

Completed

A Phase III Study of JR-131 in Renal Anemia Patients With Chronic Kidney Disease (CKD)

Anemia

Japan
Kissei Pharmaceutical Co., Ltd.
JCR Pharmaceuticals Co., Ltd.

Completed

A Long-term Study of JR-131 in Renal Anemia Patients With Chronic Kidney Disease (CKD)

Anemia

Japan
Taiwan Otsuka Pharm. Co., Ltd

Completed

A Study to Evaluate Efficacy and Safety Effects Using Mikelan® LA Ophthalmic Solution (OS) 2% Versus Timoptol® XE Ophthalmic Solution (OS) 0.5% in Ocular Hypertension Patients

Glaucoma

Taiwan
Taiwan Otsuka Pharm. Co., Ltd

Completed

Aripiprazole in the Treatment of Acutely Relapsed Patients With Schizophrenia

Schizophrenia | Schizoaffective Disorder

Taiwan

Clinical Trials Sponsored by Otsuka Pharmaceutical Co., Ltd

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