Clinical Trials Sponsored by Sheffield Children's NHS Foundation Trust

Total 3469 results

Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca

Completed

SarCaBon: A Randomised Phase II Trial of Saracatinib Versus Placebo for Cancer-induced Bone Pain (SarCaBon)

Cancer

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Bayer

Completed

Testosterone Replacement in Non-alcoholic Steatohepatitis (TEREPINS) (TEREPINS)

Hypogonadism | Nonalcoholic Steatohepatitis

United Kingdom
Sheffield Hallam University
Sheffield Teaching Hospitals NHS Foundation Trust; Rotherham Doncaster and...

Completed

Micronutrient Supplement Effects on Cognitive Outcomes in Post-Acute TBI

Traumatic Brain Injury

United Kingdom
Sheffield Children's NHS Foundation Trust
University of Hull; University of Sheffield; University of Southampton

Withdrawn

Does Vitamin D Alter Bone's Response to Vibration?

Vitamin D Deficiency | Osteoporosis

United Kingdom
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Amgen

Completed

Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty

Revision Surgery of Total Hip Arthroplasty

United Kingdom
Sheffield Hallam University
University of Sheffield; Sheffield Teaching Hospitals NHS Foundation Trust

Unknown

Probiotic Use in Parkinson's Disease

Parkinson Disease

United Kingdom
Nottingham University Hospitals NHS Trust
University Hospitals of Derby and Burton NHS Foundation Trust; Sheffield Children... and other collaborators

Unknown

Clinical Study of Solo Tympanostomy Tube Device (TTD)

Otitis Media | Middle Ear Effusion

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; British Heart Foundation

Completed

Healthy Volunteer Study of Clopidogrel and Rifampicin

Coronary Artery Disease

United Kingdom
University of Sheffield
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Completed

Reflective Tasks With Healthcare Workers During COVID-19

Depression | Wellbeing | Psychological Distress | Happiness | Emotional Distress | Affect

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Queen's Medical Center; The Rotherham NHS Foundation... and other collaborators

Completed

Breakfast Group Interventions in Stroke Rehabilitation (BISTRo)

Stroke

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Diabetes UK

Completed

Study of CBME in the Relief of Painful Diabetic Neuropathy

Diabetic Neuropathy | Painful

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
HRA Pharma

Completed

Glucocorticoid Receptor Antagonism in Subclinical Cushings

Subclinical Cushing's

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
3M ESPE

Unknown

Clinical Study 3MESPE Crowns

Dental Caries

United Kingdom
Papworth Hospital NHS Foundation Trust
University of Sheffield

Suspended

Hyperpolarized Xenon Imaging in Patients With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
University of Sheffield
Barnsley Hospital NHS Foundation Trust

Recruiting

INcorporating VoIce acTivated Communication Aids Into Everyday Communication (INVITE)

Dysarthria

United Kingdom
Sandwell & West Birmingham Hospitals NHS Trust
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Do Patient Anxiety Levels Decrease Urodynamic Test Reproducibility?

Overactive Bladder | Anxiety | Urinary Incontinence, Stress | Urinary Retention | Urinary Incontinence, Urge

United Kingdom
Loughborough University
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Ischaemic Preconditioning and Upper Body Exercise Performance in Persons With Spinal Cord Injury

Spinal Cord Injuries
Sheffield Teaching Hospitals NHS Foundation Trust
Dentsply International

Completed

Clinical Study Class II on Ceram.x Universal and Prime&Bond

Dental Caries

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Schering-Plough

Completed

Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina

Angina Pectoris

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
JP Moulton Charitable Foundation

Completed

RIPC on Activity, Fatigue and Gait in MS (MSIPC-2)

Multiple Sclerosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Novartis; Barts & The London NHS Trust; The Christie NHS Foundation Trust; Oxford...

Terminated

Pasireotide Therapy in Patients With Nelson's Syndrome

Nelson Syndrome

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Juvora Dental Solutions

Completed

OHQoL With Removable Partial Dentures; a Pilot Study

Partial Edentulism | Missing Teeth

United Kingdom
University of Sheffield
Sheffield Health and Social Care NHS Foundation Trust; Howard Morton Trust

Completed

Reducing Stasis Outcomes for Depression in Group Behavioural Activation Therapy

Depression

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

iMpact of therapeUtic Live muSic on Pain and Distress Levels During Interventions in the paediatriC Emergency Department (Music:ED)

Pain

United Kingdom
Alder Hey Children's NHS Foundation Trust

Unknown

Brain Vascular Reactivity to Hypothermic Circulatory Arrest With Antegrade Cerebral Perfusion During Aortic Arch Surgery

Cardiac | Infants | Neonates | Aortic Arch Surgery | Brain Vascular

United Kingdom
Alder Hey Children's NHS Foundation Trust

Withdrawn

Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery (PHOXEY)

Cardiac Event
Alder Hey Children's NHS Foundation Trust

Unknown

Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia

Heart Diseases | Anaesthesia | Children | Magnetic Resonance Imaging

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

Circumcision Versus Preputioplasty for BXO in Children (BXO)

Balanitis Xerotica Obliterans (BXO)

United Kingdom
Alder Hey Children's NHS Foundation Trust

Withdrawn

PLAY Therapy Intervention: Re-Modelling Patient Experience (The PLAYTIME Study) (PLAYTIME)

Pain | Anxiety | Rheumatology

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

PlayPhysio: Making Physio Fun

Cystic Fibrosis in Children

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

The LAVA (Lateral Flow Antigen Validation and Applicability) 2 Study for COVID-19 (LAVA2)

SARS-CoV-2 Infection

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19 (LAVA)

Covid19 | This is a Pilot Study Which Aims to Assess the Validity and Applicability of Lateral Flow Assays (LFAs) Which Can be Used as a Point of Care Test for COVID-19

United Kingdom
Alder Hey Children's NHS Foundation Trust

Unknown

The ASsessment and Physiotherapy managEment of Ataxia in Children Following Surgical Resection of Posterior Fossa Tumour (ASPECT)

Ataxia | Posterior Fossa Tumor

United Kingdom
Sheffield Hallam University
King's College London; Sheffield Teaching Hospitals NHS Foundation Trust

Enrolling by invitation

Pilot Testing of an Online Rehabilitation Intervention for People With Heart Failure (PORIAS-HF). (PORIAS-HF)

Heart Failure

United Kingdom
University of Sheffield
Medical Research Council; Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Tele BCI-FES for Upper -Limb Stoke Rehabilitation

Stroke

United Kingdom
Alder Hey Children's NHS Foundation Trust

Recruiting

Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations (ALOHA)

Anorectal Malformations | Hirschsprung Disease

United Kingdom
Alder Hey Children's NHS Foundation Trust

Completed

Evaluation of Faecal Volatile Organic Compounds in the Diagnosis of Paediatric Inflammatory Bowel Disease (VOCs)

Inflammatory Bowel Diseases

United Kingdom
University College, London
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Unknown

Ketogenic Diet in Infants With Epilepsy (KIWE) (KIWE)

Epilepsy

United Kingdom
Nottingham University Hospitals NHS Trust
University of Nottingham; University of Sheffield; Sheffield Teaching Hospitals...

Completed

Nutrition and Metabolic Prehabilitation in HSCT Patients UK and ROI. BSBMT Multi-centre Survey.

Nutrition Aspect of Cancer | Stem Cell Transplant Complications | Prehabilitation | Haematological Malignancy | Nutritional and Metabolic Disease | Bone Marrow Transplant Complications | Exercise Interventions

United Kingdom
Sheffield Hallam University
Chesterfield Royal Hospital NHS Foundation Trust

Not yet recruiting

What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting?

Lower Back Pain | Chronic Low-back Pain | Sleep Disturbance | Persistent Lower Back Pain
Sheffield Teaching Hospitals NHS Foundation Trust
University of Copenhagen

Active, not recruiting

Bone Pain in Multiple Myeloma- a Translational Study (BPMM)

Multiple Myeloma

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Hoffmann-La Roche

Completed

An RCT of Metformin Vs Orlistat in Obese Anovulatory Women

Obesity | Anovulation

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Manchester Metropolitan University

Completed

Pulmonary Hypertension and Measurement of Exercise Capacity Remotely (PERSPIRE)

Pulmonary Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
IntroMedic USA Inc.

Completed

An Observer Blinded Comparison of MACE and Conventional Upper Gastrointestinal Endoscopy in Upper GI Bleeding (MACE)

Gastrointestinal Diseases

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Obstetric Anaesthetist's Association

Completed

Acupuncture for Prevention of Itch in Caesarean Section

Pruritus

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Ondine Biomedical Inc.

Completed

Photodynamic Therapy Plus Root Debridement in Gum Disease Treatment V2 (PDTV2)

Periodontitis

United Kingdom
Sheffield Hallam University
Sheffield Teaching Hospitals NHS Foundation Trust; Northumbria University; Ve...

Completed

Estimating Peak Oxygen Uptake in People Living With Coronary Heart Disease

Coronary Heart Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Liverpool

Completed

Muscle in Obesity: Imaging, Function and microRNA

Muscle Function

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Nutricia UK Ltd

Completed

Investigating the Energy Expenditure of Acute Spinal Cord Injured Patients

Spinal Cord Injury, Acute

United Kingdom

Clinical Trials Sponsored by Sheffield Children's NHS Foundation Trust

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