Clinical Trials Sponsored by SymBio Pharmaceuticals

Total 19652 results

Johnson & Johnson Pharmaceutical Research & Development...
Janssen Pharmaceutica N.V., Belgium

Completed

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Pharmacokinetics | Advanced Malignancies | Solid Malignancies | Protein Kinase Inhibitors | Maximum Tolerated Dose | Antineoplastic Protocols | Clinical Trial, Phase 1
Institut Bergonié
Bristol-Myers Squibb; Amgen; Aventis Pharmaceuticals; Sanofi-Synthelabo; Chugai Pharmaceutical

Completed

Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment (PHRC2003)

Digestive System Diseases | Lymphoma | Ovarian Diseases | Pulmonary Disease | Bladder Disease | Prostatic Disease

France
Foresee Pharmaceuticals Co., Ltd.
QPS Holdings LLC; Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

Efficacy, Safety, and Pharmacokinetics of Leuprolide Mesylate in Subjects With Central Precocious Puberty

Puberty; Precocious, Central

United States, China, Taiwan, Puerto Rico
Henan Cancer Hospital
Qilu Pharmaceutical Co., Ltd.; Beijing Biostar Pharmaceuticals Co., Ltd.

Not yet recruiting

Utidelone Combined With Bevacizumab in the Treatment of ≥ 2 Lines of HER-2 Negative Advanced Breast Cancer

HER-2 Negative Breast Cancer
Navitor Pharmaceuticals, Inc.
Supernus Pharmaceuticals, Inc.

Completed

Mass Balance Study of NV-5138 in Healthy Male Subjects.

Healthy Volunteers

United Kingdom
Ferring Pharmaceuticals
Ferring Pharmaceuticals Korea, Ltd.

Completed

Long-Term Safety and Tolerability of Degarelix One-Month Dosing Regimen in Korean Patients

Prostate Cancer

Korea, Republic of
Navitor Pharmaceuticals, Inc.
Supernus Pharmaceuticals, Inc.

Recruiting

Open-Label of SPN-820 in Adults With Major Depressive Disorder

Major Depressive Disorder

United States
EMET Pharmaceuticals, LLC
Eagle Pharmaceuticals, Inc.

Completed

A BE Study Comparing Mesalamine 400 mg to ASACOL® 400 mg in Patients With Mild To Moderately Active Ulcerative Colitis

Mild to Moderate Ulcerative Colitis
Navitor Pharmaceuticals, Inc.
Supernus Pharmaceuticals, Inc.

Recruiting

Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression

Treatment Resistant Depression

United States
Teva Pharmaceuticals USA
Teva Pharmaceuticals, Inc.

Completed

Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgaris

Acne Vulgaris

United States
Ionis Pharmaceuticals, Inc.
Elan Pharmaceuticals; Hepasense

Completed

ISIS 14803-CS2, Treatment With ISIS 14803, Administered IV in Patients With Chronic Hepatitis C Virus Infections

Hepatitis C, Chronic

United States
Ferring Pharmaceuticals
Ferring Pharmaceuticals Korea, Ltd.

Completed

Efficacy and Safety of Degarelix One Month Dosing Regimen in Korean Patients With Prostate Cancer

Prostate Cancer

Korea, Republic of
Novartis Pharmaceuticals
Pacira Pharmaceuticals, Inc

Completed

Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combination With Formoterol Certihaler in Patients With Stable Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Switzerland
Regeneron Pharmaceuticals

Not yet recruiting

A First-In Human (FIH) Trial to Find Out if REGN10579 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies

Melanoma | Advanced Solid Tumors | Clear-Cell Renal-Cell Carcinoma (ccRCC)
Constellation Pharmaceuticals

Not yet recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Solid Tumor | Hematologic Malignancy | Advanced Malignancies
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Alnylam Pharmaceuticals

Recruiting

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy (cAPPricorn-1)

Cerebral Amyloid Angiopathy

Canada
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) (ROXI-CATH)

Venous Thromboembolism
Vanda Pharmaceuticals

Recruiting

A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

Dry Eye

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis) (LINKER-AL2)

Relapsed/Refractory Systemic Light Chain Amyloidosis
Regeneron Pharmaceuticals

Not yet recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma

Melanoma
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn How REGN5381 Works and How Safe it is in Adults With Heart Failure With Reduced Ejection Fraction (HFrEF)

Heart Failure

Moldova, Republic of
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-CFB in Adult Healthy Volunteers and Patients With Complement-Mediated Kidney Disease

IgA Nephropathy

New Zealand
Lexicon Pharmaceuticals

Recruiting

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP) (PROGRESS)

Diabetic Peripheral Neuropathic Pain

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma

Melanoma
Kariya Pharmaceuticals

Not yet recruiting

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Tolerance | Safety Issues
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-small Cell Lung Cancer That Can be Treated With Surgery.

Resectable Non-small Cell Lung Cancer
Regeneron Pharmaceuticals

Not yet recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma (LINKER-MGUS1)

Monoclonal Gammopathy of Undetermined Significance (MGUS) | Smoldering Multiple Myeloma (SMM)
Intercept Pharmaceuticals

Not yet recruiting

Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy

Biliary Atresia
Jazz Pharmaceuticals

Recruiting

Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

Pregnancy | Pregnancy Complication | Maternal Complications | Birth Outcomes, Adverse

United States
X4 Pharmaceuticals

Not yet recruiting

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Neutropenia
Anebulo Pharmaceuticals

Recruiting

Observational Study of THC Concentrations in Acute Cannabinoid Intoxication

Acute Cannabinoid Intoxication

United States
Iacta Pharmaceuticals

Recruiting

A Study to Assess the Safety and Efficacy of IC265 Ophthalmic Solution for Dry Eye in Adult Participants

Dry Eye Syndromes

United States
Dizal Pharmaceuticals

Recruiting

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Non-small Cell Lung Cancer

China
Jazz Pharmaceuticals

Recruiting

Ph4 PSG Combined JZP258-407

Narcolepsy | Idiopathic Hypersomnia

United States, Canada
Jazz Pharmaceuticals

Recruiting

A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy

Narcolepsy

United States, Belgium, Spain, France, Italy, Czechia
Dizal Pharmaceuticals

Recruiting

A Study of DZD8586 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

China
Jazz Pharmaceuticals

Recruiting

Long-Term Follow-Up of a Cohort of Participants Prescribed Epidyolex in France in a Real-life Setting (OPERA)

Seizures

France
Regeneron Pharmaceuticals

Recruiting

A Study to Examine the Long-term Safety, Tolerability, and Effectiveness of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (ACCESS-EXT)

Paroxysmal Nocturnal Hemoglobinuria

Taiwan, Korea, Republic of, Turkey, Spain, Thailand, Singapore, Japan, Canada, Malaysia, Poland, Italy
Jazz Pharmaceuticals

Recruiting

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma (EMERGE 101)

Ewing Sarcoma | Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United States, Canada
Dizal Pharmaceuticals

Recruiting

A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Alnylam Pharmaceuticals

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects

Transthyretin-Mediated Amyloidosis

United Kingdom
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Non-Alcoholic Fatty Liver Disease (NAFLD)

Healthy Volunteers | Non-alcoholic Fatty Liver Disease (NAFLD)

United States
Intercept Pharmaceuticals

Recruiting

FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) Study (FRESH)

Alcohol Associated Hepatitis

United States, France, United Kingdom
Cantex Pharmaceuticals

Recruiting

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma

Spain
Longboard Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Dravet Syndrome | Lennox-Gastaut Syndrome | Developmental and Epileptic Encephalopathy

United States, Australia
Cumberland Pharmaceuticals

Recruiting

Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States
Regeneron Pharmaceuticals

Recruiting

A Trial That Evaluates Disease Characteristics in Hemophilia B Adult Male Participants Receiving Prophylaxis With Standard of Care Factor IX Protein (FIX) Replacement Therapy (Honey-B)

Hemophilia B

United States, Germany, United Kingdom, Canada

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