Search clinical trials for: Bioavailability Pharmacokinetics

Total 11962 results

AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
GlaxoSmithKline

Completed

Pharmacokinetics and Safety of GSK1325756 in Elderly Subjects and Adult Subjects of in the Fed and Fasted States and in the Presence of a Proton Pump Inhibitors

Nutritional Status

United States
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Four-way Crossover, Single and Repeat Dose Study to Determine the Dose Proportionality and Absolute Bioavailability of Fluticasone Furoate Inhalation Powder Administered by Novel Dry Powder Inhaler (NDPI)

Asthma

Netherlands
GlaxoSmithKline

Terminated

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Diabetes Mellitus, Type 2

Australia
GlaxoSmithKline

Completed

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate and GW642444 Are Processed by the Body in Healthy Subjects

Asthma

Australia
GlaxoSmithKline

Completed

A Study to Evaluate the Pharmacokinetics and Absolute Bioavailability of GSK962040 Given as an Oral Dose Simultaneously With an Intravenous Microtracer Dose of [14C]-GSK962040 in Healthy Volunteers

Gastroparesis

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Tablet Formulations of GSK2248761 in Healthy Adult Subjects. SGN114435

Infection, Human Immunodeficiency Virus | Infections, Human Immunodeficiency Virus and Herpesviridae

United States
GlaxoSmithKline

Completed

A Fixed Dose Combination Amlodipine + Enalapril Bioavailability Study

Hypertension

Australia
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Study to Evaluate the Pharmacokinetics and the Absolute Bioavailability of SRT2104 Given as a 250mg Oral Suspension and Intravenous Microdose of 100 µg Carbon-14 Radio-labeled SRT2104 in Healthy Male Subjects

Diabetes Mellitus, Type 2

United Kingdom
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Bioavailability of IV and SC MABT5102A in Healthy Volunteers

Healthy Volunteer
GlaxoSmithKline

Completed

A Relative Bioavailability Study of Fluticasone Furoate and Levocabastine

Rhinitis, Allergic, Perennial and Seasonal

Australia
GlaxoSmithKline

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Repeat Escalating Doses of GSK1325756 Solution for Infusion, and Absolute Bioavailability Relative of an Oral Dose, in Healthy Adult Subjects

Infections, Respiratory Tract

United States
GlaxoSmithKline

Completed

A Study to Estimate the Relative Bioavailability, Tolerability and Safety of a Single Dose of Belimumab Self-Administered Subcutaneously (SC) by Healthy Subjects

Systemic Lupus Erythematosus

United States
GlaxoSmithKline
Quintiles, Inc.

Completed

Pharmacokinetic (PK) Study of GSK933776 in Healthy Volunteers

Atrophy, Geographic

United States
GlaxoSmithKline
SingHealth Investigational Medicine Unit, Singapore

Completed

Relative Bioavailability Study of One Amlodipine 10mg Tablet and One Rosuvastatin 20mg Tablet to Two Fixed Dose Combinations of Amlodipine (10mg) and Rosuvastatin (20mg) in Healthy Subjects Under Fasting Conditions

Hypertension

Singapore
GlaxoSmithKline

Completed

Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Repeat IV Doses

Infections, Respiratory Tract

Australia
MedImmune LLC

Completed

A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354

Healthy | Asthma

United States
University of Hohenheim
German Federal Ministry of Economics and Technology

Completed

Absorption and Excretion Kinetics of the Bioactive Ingredients of Rice Bran Extract

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
University of Hohenheim

Completed

Bioavailability of Resveratrol From Vineatrol30 Extract Incorporated Into Micelles

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
AstraZeneca

Completed

Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions

Pharmacokinetics | Relative Bioavailability | AUC | Cmax

United States
Galera Therapeutics, Inc.
INC Research Australia Pty Ltd; Nucleous Network

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of Orally-administered GC4702 in Healthy Volunteers

Healthy Volunteer

Australia
AstraZeneca

Completed

To Determine the Relative Bioavailability of Different Formulations of AZD9291 and the Effect of Food.

Healthy Volunteers

United States
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
Pfizer

Completed

A Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06700841, With Bioavailability/Food Effect Investigation

Plaque Psoriasis

United States
Genentech, Inc.

Completed

A Study to Determine the Relative Bioavailability of a Tablet Formulation of GDC-0941 and the Effect of Ketoconazole on the Pharmacokinetics of the GDC-0941 Tablet

Healthy Volunteer

United States
Merck KGaA, Darmstadt, Germany

Completed

Relative Bioavailability Trial of Oral Dispersible Praziquantel Tablets in Healthy Volunteers

Healthy

Germany
Genentech, Inc.

Completed

A Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and the Effect of Food and Proton Pump Inhibition on GDC-0941 Tablet Pharmacokinetics in Healthy Volunteers

Healthy Volunteers

United States
Heptares Therapeutics Limited

Completed

Relative Bioavailability of HTL0018318 Oral Aqueous Solution Versus Capsules

Bioavailability and Pharmacokinetics

United Kingdom
Takeda

Completed

Bioavailability and Pharmacokinetics of Vedolizumab in Healthy Participants Following Single Subcutaneous Administration

Healthy

United Kingdom
Janssen Scientific Affairs, LLC
Bayer

Completed

Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants

Pharmacokinetics | Healthy Participants | Bioavailability

United States
Region Skane

Completed

Comparative Bioavailability Study of Two Misoprostol Formulations

Labour, Induced

Sweden
University of Hohenheim

Unknown

Bioavailability of Carotenoids and Flavonoids From Fresh Oranges and Orange Juice.

Healthy

Germany
University of Hohenheim
German Federal Ministry of Education and Research

Completed

Oral Bioavailability of Curcumin From Micronized Powder and Liquid Micelles in Healthy Young Women and Men

Pharmacokinetics of Novel Curcumin Formulations | Safety of Novel Curcumin Formulations

Germany
University of Hohenheim
German Federal Ministry of Education and Research

Completed

Improved Oral Bioavailability of Curcumin Incorporated Into Micelles

Pharmacokinetics of New Curcumin Formulations | Safety of New Curcumin Formulations

Germany
Flatley Discovery Lab LLC

Completed

Bioavailability and Pharmacokinetics Study of FDL169 in Healthy Subjects and Subjects With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Mallinckrodt

Completed

Pharmacokinetic, Bioavailability, and Safety Study of COV155 Administered in Healthy Subjects Under Fed and Fasted Conditions

Pharmacokinetics
Mallinckrodt

Completed

Pharmacokinetic, Bioavailability, and Safety Study of COV155 Administered in Healthy Subjects Under Fed and Fasted Conditions

Pharmacokinetics
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
AstraZeneca

Completed

A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers

Healthy Volunteers Bioequivalence or Bioavailability Study

United Kingdom
Pfizer

Completed

A Study To Estimate The Effects Of Food On Drug Fesoterodine Fumarate And The Pharmacokinetics Of 5-Hydroxymethyl Tolterodine (5-HMT) In Healthy Volunteers

Urinary Bladder, Overactive

Singapore
Concert Pharmaceuticals

Completed

Food Effect Study of CTP-656 in Healthy Male Volunteers

Healthy

Australia
Endo Pharmaceuticals
SFBC Anapharm

Completed

Evaluating the Effect of Food on Absorption of Megace ES

Pharmacokinetics | Bioavailability | Absorption

Canada
AstraZeneca

Completed

A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.

Healthy Volunteers Bioavailability Study

United Kingdom
Pain Therapeutics

Completed

Single-Dose, Crossover Study To Compare Bioavailability Of Two Formulations Under Fed And Fasted Conditions

Healthy

United States
Pain Therapeutics

Completed

Effects of Ethanol on Oxycodone Pharmacokinetics in Healthy Volunteers

Healthy

United States
Pain Therapeutics

Completed

Effects of Food on Oxycodone Pharmacokinetics in Healthy Volunteers

Healthy

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study To Estimate The Relative Bioavailability of Ertugliflozin (PF-04971729, MK-8835) in Healthy Adult Participants (MK-8835-039)

Healthy
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

Bioavailability and Pharmacokinetics Study of Sirukumab in Healthy Male Participants

Healthy

United States
University of Parma

Completed

Bioavailability of Phenolic Compounds in Bread

Dietary Modification

Italy

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