Search clinical trials for: Biological Targets

Total 4539 results

Mayo Clinic

Recruiting

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

Biochemically Recurrent Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8 | Oligometastatic Prostate Carcinoma | Recurrent Prostate Adenocarcinoma

United States
New York Stem Cell Foundation Research Institute

Recruiting

NYSCF Scientific Discovery Biobank

PTSD | Multiple Sclerosis | Cervical Cancer | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Macular Degeneration | Diabetes Mellitus, Type 1 | Parkinson Disease | Amyotrophic Lateral Sclerosis | Dementia | Ovarian Cancer | Alzheimer Disease | ALS | Vulvar Cancer | Post Traumatic Stress Disorder | Lewy Body Disease and other conditions

United States
New York Stem Cell Foundation Research Institute
Charcot-Marie-Tooth Association

Recruiting

Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for iPSC Generation and Biobanking

Healthy | Charcot-Marie-Tooth Disease

United States
National Cancer Institute (NCI)

Recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Elvira Umyarova
Sanofi

Recruiting

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Recurrent Multiple Myeloma

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Alesund Hospital

Not yet recruiting

Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women (PRERISK)

Preeclampsia

Norway
Roswell Park Cancer Institute

Not yet recruiting

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Tumors

Malignant Solid Neoplasm | Lung Neuroendocrine Neoplasm | Digestive System Neuroendocrine Neoplasm | Pancreatic Neuroendocrine Neoplasm

United States
Mayo Clinic

Recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Identification and Clinical Validation of Biomarkers Associated With Clinical Severity in Adults Infected With RSV (ARF-RSV)

Respiratory Syncytial Virus Infections

France
Centre Hospitalier Universitaire Dijon

Not yet recruiting

Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer (CIRCULATE PAC)

Colon or Upper Rectum Adenocarcinoma

France
Xiamen University
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Not yet recruiting

Plateau Antibody Levels of a Recombinant (E.Coli) HPV Nonavalent Vaccine Versus Gardasil®9 in Young Women

Cervical Cancer | Condylomata Acuminata

China
National Cancer Institute (NCI)

Not yet recruiting

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Breast Atypical Hyperplasia

United States
Shanghai Institute Of Biological Products

Not yet recruiting

Clinical Trial of SIBP-03 in Patients With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma
Fudan University
Shanxi Province Cancer Hospital; Inner Mongolia Cancer Hospital Affiliated...

Recruiting

A Retrospective and Prospective Real-world Study of Molecular Typing in the Treatment of Advanced Thyroid Cancer

Advanced Thyroid Cancer Patients Who Received Target Therapy

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
The Institute of Molecular and Translational Medicine...

Not yet recruiting

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Critical Illness | Acute Respiratory Failure

Czechia
Mayo Clinic

Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent... and other conditions

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy

Hypogonadism | Malignant Testicular Germ Cell Tumor

United States
PepsiCo Global R&D

Recruiting

Aspire2B Personalization Pilot Study Program

Behavior | Lifestyle | App Proficiency

United States
Centre Hospitalier Régional Metz-Thionville
University of Lorraine

Recruiting

Kinetics of Urinary Excretion of Gadolinium Contrast Agents Used in MRI Examinations (GADODURABLE)

Magnetic Resonance Imaging

France
IRCCS San Raffaele

Recruiting

Creation of a Biobank of Fertile Men

Fertility

Italy
University of California, Berkeley
University of British Columbia; University College, London; Wellcome Trust; Salk... and other collaborators

Not yet recruiting

Healthy Lifestyles for Bipolar Disorder (HL)

Time Restricted Eating | Diet, Mediterranean

United States
IRCCS San Raffaele

Recruiting

Bank of Biological Material From Patients and Healthy Donors for the Study of Urological and Uro-oncological Pathologies

Urologic Diseases | Infertility | Urologic Cancer

Italy
Biocad

Recruiting

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A (EDELWEISS)

Hemophilia A

Russian Federation
Clinical Hospital Centre Zagreb

Recruiting

Apixaban for the Prevention of Latent Biological Valve Thrombosis

Aortic Valve Replacement | Antithrombotic Therapy | Rapid Deployment Valves | Bioprosthetic Valve Thrombosis

Croatia
National Cancer Institute (NCI)

Not yet recruiting

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Estrogen Receptor-Positive Breast Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple Myeloma

Multiple Myeloma

United States
University Hospital, Strasbourg, France

Recruiting

Performance Evaluation of the Biological Diagnosis of HIT (HIT)

Heparin-induced Thrombocytopenia (HIT)

France
University of Washington
Breast Cancer Research Foundation

Not yet recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic HER2-Negative Breast Carcinoma | Metastatic Hormone Receptor-Positive Breast Carcinoma | Locally Advanced Unresectable HER2-Negative Breast Carcinoma | Locally Advanced Unresectable Hormone Receptor-Positive...

United States
University of Kansas Medical Center
National Cancer Institute (NCI)

Recruiting

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Locally Advanced Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Recurrent Cholangiocarcinoma

United States
IRCCS San Raffaele

Recruiting

SARS-CoV-2, TESTOSTERONE AND MALE FRAGILITY (PROTEGGIMI)

COVID-19 | Infertility, Male | Testosterone Deficiency

Italy
Mamta Parikh
National Cancer Institute (NCI)

Recruiting

Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Advanced Prostate Adenocarcinoma

United States
National Cancer Institute (NCI)

Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Neuroblastoma | Ganglioneuroblastoma, Nodular

United States
National Cancer Institute (NCI)

Recruiting

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Trieste; IRCCS Fondazione Stella Maris; CNR Institute of Neuroscience...

Recruiting

Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) (GAPsy)

Healthy | Depression, Anxiety

Italy
Technische Universität Dresden

Recruiting

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Sleep Apnea, Obstructive

Germany
Northwestern University
National Cancer Institute (NCI)

Recruiting

Pembrolizumab Followed by Chemotherapy for the Treatment of Patients With Classical Hodgkin Lymphoma

Classic Hodgkin Lymphoma

United States
Shalamar Institute of Health Sciences

Not yet recruiting

Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis

Migraine | Prophylaxis

Pakistan
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
CerbaXpert

Recruiting

Infectious Prospective Collection for Biological Analysis (Infectieux1)

Infectious Disease

France
University of Kansas Medical Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Recruiting

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
Steno Diabetes Center Copenhagen
University of Copenhagen; University of Leeds; Glostrup University Hospital,... and other collaborators

Recruiting

Restricted Eating Time in the Treatment of Type 2 Diabetes (RESET2)

Type 2 Diabetes

Denmark
University of Washington
Novartis; Institute for Prostate Cancer Research (IPCR)

Not yet recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking

Cigarette Smoking-Related Carcinoma

United States
CerbaXpert

Not yet recruiting

Collection of Additional Biological Samples From Potentially COVID-19 Patients for Monitoring of Biological Parameters Carried Out as Part of the Routine (CEB Covid-19)

SARS CoV 2 Infection
Xiaomei Shao

Recruiting

Evaluation on Biological Characteristics of Acupoints in Premature Ovarian Insufficiency

Premature Ovarian Insufficiency

China
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Precision Imaging for Early Detection and Targeted Treatment Monitoring in Pancreatic Cancer (PANC-O-MICS)

Pancreas Cancer

France
Region Stockholm

Recruiting

Biological Mechanisms Behind Resynchronization Therapy in Heart Failure

Heart Failure | Cardiac Remodeling, Ventricular

Sweden
IRCCS San Raffaele

Not yet recruiting

WEST-KOaST Study: WES Analysis of Testicular Cancer Patientsand Their First-degree Family Members (West-KOaSt)

Testicular Cancer
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8

United States

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