Search clinical trials for: Comparative efficacy;safety;PK; immunogenicity; biosimilar

Total 3406 results

Rajavithi Hospital

Recruiting

Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users

Abnormal Uterine Bleeding | Tranexamic Acid | Estrogen | Depot Medroxyprogesterone Acetate

Thailand
Italfarmaco

Recruiting

A Multicentre, Prospective, Open-label, Non-comparative Study

Contraception

Italy
Asan Medical Center
Samsung Medical Center; Seoul National University Hospital; Kyungpook National... and other collaborators

Recruiting

Efficacy and Safety of Formulation Switching Between SC Infliximab and IV Infliximab in Patients With CD (CHAMELEON)

Crohn's Disease

Korea, Republic of
Tomey Corporation

Recruiting

Comparative Study of the Tomey OA-2000, Tomey CASIA2, and the LenStar LS900

Cataract | Pseudophakia | Aphakic Eye

United States
National Cancer Institute (NCI)

Recruiting

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Stage IV Nasopharyngeal Carcinoma AJCC v8 | Stage II Nasopharyngeal Carcinoma AJCC v8 | Stage III Nasopharyngeal Carcinoma AJCC v8

United States
Perrigo CSCI

Recruiting

Comparative Study for the Evaluation of Two Medical Devices on the Treatment of Head Lice Infestation

Head Lice Infestation

Mauritius
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma

United States
Egymedicalpedia

Recruiting

Comparative Study Between Preoperative and Postoperative Rectal Misoprostol

Blood Loss, Surgical | Blood Loss, Postoperative

Egypt
Mayo Clinic

Recruiting

Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma

Multiple Myeloma

United States
Biocon Biologics UK Ltd

Not yet recruiting

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients
Intuitive Surgical

Recruiting

Lung cAncer Robotic Comparative Study (LARCS)

Lung Cancer

United Kingdom
Sohag University

Not yet recruiting

Ketamine and Dexmedetomidine Comparative Study

Post Operative Pain
Sun Yat-sen University

Recruiting

Perioperative Sintilimab Plus Bevacizumab Biosimilar and TACE-HAIC for HCC Patients With PVTT: A Phase-2 Clinical Trial

Hepatocellular Carcinoma

China
National Cancer Institute (NCI)

Recruiting

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma

United States, Hong Kong
Ankara Yildirim Beyazıt University

Recruiting

Comparative Effect of Palatal Injection in Pediatric Patient

Local Anesthetic Complication

Turkey
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM); Patient-Centered Outcomes Research Institute and other collaborators

Not yet recruiting

Comparative Effectiveness of Individual Versus Group-Level Interventions to Reduce Human Immunodeficiency Virus (HIV)/ Sexually Transmitted Infections (STI) Incidence

HIV | Other STIs

United States
Yih-Ing Hser
National Institute on Drug Abuse (NIDA); University of California, Los Angeles and other collaborators

Not yet recruiting

Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) (RXR)

Substance-Related Disorders | Opioid-Related Disorders | Narcotic-Related Disorders

United States
Abanoub emad fayez

Not yet recruiting

Comparative Study Between Wide Local Excision and Minimal Excision of Pilonidal Sinus

Pilonidal Sinus
Guangdong Second Provincial General Hospital

Recruiting

Comparative Effects of Ciprofol and Propofol on Pain Intensity on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study

Acute Pain | Anesthesia | Risk Reduction

China
GC Aesthetics

Not yet recruiting

Post-market Prospective Clinical Study of Nagor Perle Mammary Implants (PERLE10PMCF)

Breast Augmentation | Breast Reconstruction | Breast Reconstruction Following Mastectomy | Breast Reconstruction Surgery | Breast Implants | Breast Revision | Breast Reconstruction With Silicone Implants | Breast Reconstruction After Mastectomy
Fondazione Don Carlo Gnocchi Onlus

Not yet recruiting

Efficacy of EFA in Acquired Brain Injury

Lung Diseases, Obstructive | Acquired Brain Injury | Comparative Effectiveness Research

Italy
Bapuji Dental College & Hospital Davengere Karnataka

Not yet recruiting

Comparative Evaluation of the Effect of 970 nm Diode Laser With or Without N Acetyl Cysteine on Post Operative Pain After Endodontic Treatment in Teeth With Symptomatic Apical Periodontiti

Evaluation of Post Endodontic Pain

India
Children's Hospital of Chongqing Medical University

Recruiting

Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration

Congenital Diaphragmatic Hernia

China
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
Aesculap AG

Not yet recruiting

Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty (ORMAK)

Joint Diseases | Osteoarthritis, Knee | Rheumatoid Arthritis of Knee | Posttraumatic Arthropathy

Germany
Sohag University

Not yet recruiting

Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture Ribs

Multiple Fracture Ribs
Ain Shams University

Recruiting

A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia

Post Operative Pain, Acute

Egypt
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
Hasan Aksoy

Recruiting

Association Between Biologic Therapy and Demodex Density in Psoriasis Patients: A Comparative Study

Demodicidosis

Turkey
Riphah International University

Recruiting

Comparative Effects of BBT and Active Cycle of Breathing Technique on Dyspnea and Quality of Life in COPD

COPD

Pakistan
Stanford University

Recruiting

A Comparative Study on the Effectiveness of Video vs Text-Based Education in Heart Failure (EDUCATE-HF)

Heart Failure

United States
Ain Shams University

Not yet recruiting

A Comparative Study Between Honey and Alcohol as Topical Skin Disinfectant

Disinfectant Causing Toxic Effect
Mohamed Gamal Thabet

Recruiting

Comparative Study Between Arthroscopic Versus Open Surgical Discopexy for Treatment of Temporomandibular Joint Anterior Disc Displacement Without Reduction (RCT)

Efficacy of TMJ Arthroscopy

Egypt
Hansa Biopharma AB

Recruiting

A Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation and a Non-comparative Transplanted Patient Group (PAES-LTFU)

Long Term Efficacy and Safety

Spain, Sweden, Czechia
Institut de Cancérologie de Lorraine

Recruiting

Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted. (PROTOTOX)

Quality of Life | Cancer | Hearing Disorders | Ototoxicity, Drug-Induced

France
University of California, San Francisco
Patient-Centered Outcomes Research Institute; Johns Hopkins University; Mayo... and other collaborators

Recruiting

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

Myocardial Infarction | Coronary Artery Disease | Heart Valve Diseases | Angina, Stable | Heart Failure, Systolic | Heart Transplant

United States
Riphah International University

Recruiting

Comparative Effects of Dual Task and PNF on Balance ,Cognition and Motor Function in Chronic Stroke Patients .

Stroke

Pakistan
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Comparative Evaluation of Microsurgery vs Diode Laser Technique of Gingival Depigmentation

Melanosis | Gingival Pigmentation

India
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Comparative Evaluation of Microsurgery vs Conventional Surgical Technique of Gingival Depigmentation

Melanosis | Gingival Pigmentation

India
VA Office of Research and Development

Recruiting

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes (BRAVO)

End-Stage Renal Disease | End-Stage Kidney Disease

United States
Nanchong Central Hospital
Guang'an People's Hospital; Pengan County People's Hospital; People's Hospital... and other collaborators

Recruiting

A Comparative Study of 3-point With 1-point Mesh Fixation in TAPP for Gilbert Type III Inguinal Hernia

Infections | Recurrence | Chronic Pain | Hernia, Inguinal | Hematoma | Seroma

China
University of Michigan
Patient-Centered Outcomes Research Institute; University of Pennsylvania; University... and other collaborators

Recruiting

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders (ENHANCE)

Delirium | Neurocognitive Disorders | Alzheimer Disease | Caregiver Burden | Aging | Mild Cognitive Impairment | Patient Satisfaction | Implementation Science | Family Members | Family Support

United States
Assiut University

Not yet recruiting

Fractional Co2 Laser Versus Microbotox Injection in the Treatment of Wide Facial Pores: A Split Face Comparative Study

Skin Abnormalities
Assiut University

Not yet recruiting

Comparative Study Between Autologous Adipose Tissue Graft Versus Microfracture for Treatment of Articular Cartilage Defects

Knee Osteoarthritis
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
Yonsei University
dotter

Recruiting

Comparative Study of Rosuvastatin/Ezetimib 20/10 mg and Atovastatin/Ezetimib 40/10 mg (TOLERANT Trial)

Coronary Artery Disease | Dyslipidemias

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8

United States
Mayo Clinic

Recruiting

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

AL Amyloidosis

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Metastatic Merkel Cell Carcinoma | Metastatic Skin Squamous Cell Carcinoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Basal Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Unresectable... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma

Nodular Lymphocyte Predominant B-Cell Lymphoma | Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma | Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma

United States

Search clinical trials for: Comparative efficacy;safety;PK; immunogenicity; biosimilar

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