Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration

The imaging manifestations of diaphragmatic hernia and diaphragmatic distension were retrospectively analyzed and summarized, combined with the surgical findings, to summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, so as to achieve the purpose of differential diagnosis.Research contents: (1) To summarize the characteristics of indirect imaging signs in patients with diaphragmatic hernia, to sum up the incidence of each sign, to find new signs and the prognosis of each sign; (2) Summarize the characteristics of indirect imaging signs in patients with diaphragmatic distension, summarize the incidence of each sign, and search for new signs and the prognosis of each sign; (3) To summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, as well as the differences in their incidence, and combined with their surgical findings, to summarize their image identification points

Study Overview

• Status: Recruiting
• Conditions: Congenital Diaphragmatic Hernia
• Intervention / Treatment: Other: imaging diagnosis

• Study Type: Observational
• Enrollment (Estimated): 300

Contacts and Locations

• Study Contact: Name: song yan; Phone Number: 13637921652; Email: doctorsongyan@163.com
• Study Contact Backup: Name: shi yuan

Study Locations

• China
  • Chongqing, China
    • Recruiting
    • Children's Hospital of Chongqing Medical University
    • Contact: song yan

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

The Bochdalek hernia and the congenital diaphragmatic eventration were included in the study. They had undergone surgical treatment.The imaging results and the surgical results were analysis

Description

Inclusion Criteria:

• Clinical diagnosis of diaphragmatic hernia with surgical treatment
• Clinical diagnosis of congenital diaphragmatic eventration with surgical treatment

Exclusion Criteria:

• Diaphragmatic hernia or congenital diaphragmatic eventration without surgical treatment
• Diaphragmatic hernia or congenital diaphragmatic eventration without imaging examination

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
The Bochdalek hernia group	Other: imaging diagnosis; no intervention
the congenital diaphragmatic eventration group

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The position of the stomach	The position of the stomach through imaging examination and operation	1 day during the test
The position of the small intestine	The position of the small intestine through imaging examination and operation	1 day during the test

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The morphology of the small intestine	The normal morphology, dilation and stenosis of the small intestine through imaging examination	1 day during the test
The position of the colon	The position of the colon through imaging examination and operation	1 day during the test
The morphology of the colon	The normal morphology, dilation and stenosis of the colon through imaging examination	1 day during the test

Collaborators and Investigators

• Sponsor: Children's Hospital of Chongqing Medical University

Publications and helpful links

General Publications

• Alamo L, Gudinchet F, Meuli R. Imaging findings in fetal diaphragmatic abnormalities. Pediatr Radiol. 2015 Dec;45(13):1887-900. doi: 10.1007/s00247-015-3418-5. Epub 2015 Aug 9.
• Brown BP, Clark MT, Wise RL, Timsina LR, Reher TA, Vandewalle RJ, Brown JJ, Saenz ZM, Gray BW. A multifactorial severity score for left congenital diaphragmatic hernia in a high-risk population using fetal magnetic resonance imaging. Pediatr Radiol. 2019 Dec;49(13):1718-1725. doi: 10.1007/s00247-019-04478-2. Epub 2019 Aug 14.
• Goodfellow T, Hyde I, Burge DM, Freeman NV. Congenital diaphragmatic hernia: the prognostic significance of the site of the stomach. Br J Radiol. 1987 Oct;60(718):993-5. doi: 10.1259/0007-1285-60-718-993.

Study record dates

Study Major Dates

• Study Start (Actual): March 18, 2022
• Primary Completion (Estimated): October 31, 2023
• Study Completion (Estimated): December 31, 2023

Study Registration Dates

• First Submitted: July 20, 2023
• First Submitted That Met QC Criteria: August 9, 2023
• First Posted (Actual): August 14, 2023

Study Record Updates

• Last Update Posted (Actual): August 14, 2023
• Last Update Submitted That Met QC Criteria: August 9, 2023
• Last Verified: August 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Digestive System Diseases; Congenital Abnormalities; Pathological Conditions, Anatomical; Internal Hernia; Digestive System Abnormalities; Hernia; Hernias, Diaphragmatic, Congenital; Hernia, Diaphragmatic; Diaphragmatic Eventration
• Other Study ID Numbers: ysong

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No