Search clinical trials for: Dual MEK

Total 102653 results

Chang Gung Memorial Hospital

Completed

Efficacies of Hybrid and High-dose Dual Therapies for the First-line Anti-H Pylori Treatment

Helicobacter Pylori Infection

Taiwan
Harbin Medical University
LanZhou University; Hebei General Hospital; The First Hospital of Jilin University and other collaborators

Active, not recruiting

EROSION II: OCT Guided PPCI in STEMI

ST-segment Elevation Myocardial Infarction

China
University of Chicago
Abbott

Completed

A Research Study to See if a Change in Therapy for HIV Infection Can Improve the Immune Response to Treatment

HIV Infections

United States
University of Alberta

Withdrawn

The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack (MENA-TIA)

Transient Ischemic Attacks | Minor Stroke

Canada
Shenyang Northern Hospital
Changhai Hospital; ANKON medical technologies (Shanghai)Co.,LTD

Completed

Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation (OPT-PEACE)

Ischemic Heart Disease | Gastrointestinal Injury

China
Abbott Medical Devices

Completed

XIENCE 28 USA Study

Coronary Artery Disease | Renal Insufficiency | Ischemic Stroke | Anemia | Thrombocytopenia | Coagulation Disorder | Hemorrhagic Stroke | Bleeding Disorder | Hematological Diseases

United States, Hong Kong, Canada, China, Spain, Belgium, Germany, Portugal, Switzerland, Taiwan, United Kingdom, Austria, Italy, Netherlands, Singapore
Radboud University Medical Center

Active, not recruiting

Trained Immunity by Dual-pathway Inhibition in Coronary Artery Disease (DUALCAD)

Coronary Artery Disease

Netherlands
Pedro Cahn
ViiV Healthcare

Withdrawn

Dolutegravir-Lamivudine as Dual Therapy in naïve HIV-Infected Patients With Documented M184V Mutation:A Pilot Study (PADDLE184V)

HIV-1 Infection

Argentina
Vanderbilt-Ingram Cancer Center
AstraZeneca; Syndax Pharmaceuticals

Terminated

Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers

Fallopian Tube Cancer | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Endometrioid Adenocarcinoma | Recurrent Endometrial Carcinoma | Ovarian Clear Cell Adenocarcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Primary Peritoneal... and other conditions

United States
University of Maryland, Baltimore

Withdrawn

Long Acting Paliperidone in Dually Diagnosed People With Schizophrenia: An Open-label Pilot Study

Schizophrenia

United States
Imperial College London
North Eastern German Society of Gynaecological Oncology; Takeda Pharmaceuticals...

Active, not recruiting

Dual mTorc Inhibition in advanCed/Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (of Clear Cell, Endometrioid and High Grade Serous Type, and Carcinosarcoma) (DICE)

Ovarian Neoplasms | Fallopian Tube Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Serous Adenocarcinoma | Primary Peritoneal Serous Adenocarcinoma | Primary Peritoneal Carcinoma | Ovarian Carcinosarcoma

United Kingdom, Germany
Organon and Co

Completed

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

Dyslipidemia
University Hospital, Bordeaux

Completed

Hyper-synchronicity in Hypertrophic Cardiomyopathy (HCM) : Description, Mechanism and Origin With a Multi-imaging Approach to Predict Dual Chamber Pacing Response (HSYNC)

Hypertrophic Cardiomyopathy | Mechanical Hyper-synchronicity

France
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes (SURPASS-2)

Type 2 Diabetes

United States, Puerto Rico, Australia, United Kingdom, Mexico, Argentina, Brazil, Israel, Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
Yonsei University

Completed

Hemostatic Powder Following Injection Therapy Versus Conventional Dual Therapy for Endoscopic Hemostasis for Non-variceal Upper Gastrointestinal Bleeding

Upper Gastrointestinal Bleeding

Korea, Republic of
Radboud University Medical Center

Completed

DUAL Pathway Inhibition to Improve Endothelial Function in Peripheral Artery Disease (DUAL-PAD)

Peripheral Artery Disease

Netherlands
Rose Research Center, LLC
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use (DUAL)

Cigarette Smoking | Nicotine Addiction

United States
Assistance Publique - Hôpitaux de Paris
Bayer; Action Research Group

Completed

Assessment of Dual Antiplatelet Therapy Versus Rivaroxaban In Atrial Fibrillation Patients Treated With Left Atrial Appendage Closure (ADRIFT)

Hemorrhage | Atrial Fibrillation | Atrial Appendage

France
Dr. Grace Parraga
Novartis Pharmaceuticals

Withdrawn

Investigating the Effects of QVM149 on MRI Ventilation Defects (XPERTT)

Asthma

Canada
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...

Completed

Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected People

HIV Infections

United States
Instituto Nacional de Cardiologia Ignacio Chavez

Terminated

Drug-eluting Balloon Versus Drug-eluting Stent for High Bleeding Risk Angioplasty (DEBORA)

Coronary Artery Disease (CAD) | Percutaneous Coronary Intervention (PCI) | High Bleeding Risk

Mexico
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone (SURPASS-1)

Type 2 Diabetes Mellitus

United States, Japan, India, Puerto Rico, Mexico
Dartmouth-Hitchcock Medical Center
Harvard Medical School (HMS and HSDM); National Institute on Drug Abuse (NIDA) and other collaborators

Completed

Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?

Schizophrenia | Dual Diagnosis | Psychotic Disorder | Cannabis Use Disorder

United States
Theravance Biopharma
GlaxoSmithKline

Completed

A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Shanghai Jiao Tong University School of Medicine

Completed

High Dose of Dual Therapy Plus Metronidazole for Helicobacter Pylori RescueTreatment

Helicobacter Pylori Infection

China
Hospitales Universitarios Virgen del Rocío
Instituto de Salud Carlos III

Completed

Tripe Versus Dual Antiretroviral Therapy in HIV-infected Patients With Virological Suppression (Tridual) (Tridual)

HIV Infections

Spain
Duke University
Georgetown University; University of Michigan

Withdrawn

Impact of New Product Standards for JUUL Among Dual JUUL/Combusted Cigarette Users

Smoking | Cigarette Smoking | E-cigarette Use
University of Texas Southwestern Medical Center
Stanley Medical Research Institute

Completed

Ondansetron for Bipolar Disorder and Alcohol Use Disorders

Bipolar Disorder | Alcohol Use Disorder | Dual Diagnosis

United States
ECRI bv
University of Bern; European Cardiovascular Research Center; Terumo Medical Corporation and other collaborators

Completed

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT)

Coronary Artery Disease | PCI | High Bleeding Risk

Netherlands, France, United Kingdom, Australia, Singapore, Japan, Italy, Poland, Spain, Switzerland, Israel, Argentina, Austria, Bahrain, Bangladesh, Belgium, Bulgaria, Czechia, Denmark, Estonia, Germany, Hungary, India, Korea, Republic... and more
Rhizen Pharmaceuticals SA

Completed

Efficacy and Safety Study of Tenalisib (RP6530), a Novel PI3K δ/γ Dual Inhibitor in Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (iNHL)

Non Hodgkin Lymphoma

United States, Australia
The First Affiliated Hospital of Dalian Medical...

Completed

Ticagrelor in Elderly Patients Undergoing Percutaneous Coronary Intervention

Percutaneous Coronary Intervention | Aged | Platelet Aggregation Inhibitors | Dual Anti-Platelet Therapy

China
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA); Columbia University; University of Vermont and other collaborators

Completed

Cannabis and Schizophrenia: Self-Medication and Agonist Treatment

Schizophrenia | Schizoaffective Disorder | Dual Diagnosis | Psychotic Disorder | Cannabis Use Disorder

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Terminated

Effects of E-Cigarette Power and Nicotine Content in Dual Users and Vapers

Electronic Cigarettes

United States
Weill Medical College of Cornell University
Celgene Corporation

Completed

Phase II Study of Biaxin, Revlimid, and Dexamethasone for Untreated Multiple Myeloma

Multiple Myeloma

United States
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Janssen-Cilag Ltd.

Completed

Capacity of the Dual Combination Raltegravir/Etravirine to Maintain Virological Success in HIV-1 Infected Patients of at Least 45 Years of Age- ANRS 163 ETRAL

HIV-1 Infection

Spain, France
Actelion

Completed

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension (TRITON)

Pulmonary Arterial Hypertension

United States, Spain, Denmark, Canada, Germany, United Kingdom, Belgium, Austria, Netherlands, Australia, France, Ireland, Sweden, Italy, Switzerland
Xijing Hospital of Digestive Diseases

Enrolling by invitation

Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis | Dyspepsia | Gastric Cancer | Peptic Ulcer | Helicobacter Pylori Infection

China
The Catholic University of Korea
Chonnam National University Hospital

Completed

TicAgrelor Versus CLOpidogrel in Stabilized Patients With Acute Myocardial Infarction: TALOS-AMI

Acute Myocardial Infarction

Korea, Republic of
Samsung Medical Center

Completed

Study of AZD6738 and Olaparib Combination Therapy in Relapsed Small Cell Lung Cancer Patients [SUKSES-N2]

SCLC

Korea, Republic of
Dong-A University

Unknown

3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI (BULK-STEMI)

ST Elevation Myocardial Infarction

Korea, Republic of
Jihong Liu

Unknown

Anlotinib and Niraparib Dual Therapy Evaluation in Platinum-resistant Recurrent Ovarian Cancer (ANNIE)

Platinum-resistant Ovarian Cancer

China
University of Manitoba
University of Oregon; Centre for Addiction and Mental Health; Research Manitoba

Terminated

Building Regulation in Dual Generations (BRIDGE)

Depression | Child Development | Self-regulation

Canada
University of Turin, Italy

Withdrawn

Pharmacokinetics of Maraviroc and Boosted Atazanavir Dual Regimen in Stable HIV-infected Patients

HIV Infection

Italy
Gilead Sciences

Completed

Study to Evaluate the Effect of Ranolazine and Dronedarone When Given Alone and in Combination in Patients With Paroxysmal Atrial Fibrillation (HARMONY)

Atrial Fibrillation

United States, Italy, Poland, Germany, Israel, Netherlands, United Kingdom
Brown University
National Institute on Drug Abuse (NIDA)

Completed

Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia

Schizophrenia | Tobacco Use Disorder

United States
CeloNova BioSciences, Inc.
ClinLogix. LLC

Terminated

COBRA SHIELD OCT Study

Stable Angina

Finland
M.D. Anderson Cancer Center

Terminated

Biochemotherapy With Temozolomide for Metastatic Melanoma

Melanoma

United States
Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Comparison Three vs Twelve Months of Dual Anti-Platelet Therapy After Stent Implantation

Percutaneous Coronary Intervention | Drug-Eluting Stents

China

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