Search clinical trials for: Dual-chamber syringe

Total 486 results

Johns Hopkins All Children's Hospital

Completed

COVID-19 Anticoagulation in Children - Thromboprophlaxis (COVAC-TP) Trial

COVID-19 | Thromboses, Venous | Infection Viral

United States
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Active, not recruiting

Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD

Limbal Stem Cell Deficiency

United States, Germany
CSL Behring

Completed

A Study to Compare the Pharmacokinetics of CSL312 Administered by Prefilled Syringe Assembled to Autoinjector to the Pharmacokinetics Administered by Prefilled Syringe Assembled to Needle Safety Device in Healthy Subjects

Healthy Participants

United States
Shire
Takeda Development Center Americas, Inc.

Completed

A Study to Evaluate the Bioavailability of Teduglutide Administered Subcutaneously by Syringe Injection Versus Pen Injector in Healthy Adult Participants

Healthy Volunteers

United States
Sunnybrook Health Sciences Centre
Sanofi

Active, not recruiting

Trial of Hypofractionated IMRT Boost Versus Conventional IMRT Boost for Localized High Risk Prostate Cancer (RCT-PHART2)

Prostate Cancer
Pfizer

Completed

Pharmacokinetic Comparability Study in Healthy Participants - PF-06881894 On-Body Injector Relative to Prefilled Syringe

Healthy Volunteers

United States
Chiayi Christian Hospital

Completed

Comparing the Effects of Water Temperature and Actives in Glucose Solution on Pregnant Women

Gestational Diabetes Mellitus

Taiwan
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
Takeda

Completed

A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Needle Safety Device (PFS+NSD) in Healthy Participants

Healthy Volunteers

United States
Hospital for Special Surgery, New York
Weill Medical College of Cornell University

Completed

PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial

Osteoporotic Fractures

United States
Crossject

Completed

Bioavailability Study of Midazolam Administered as a Solution by Conventional Syringe or ZENEO®

Healthy

South Africa
Eli Lilly and Company

Completed

A Study to Compare Two Formulations of Mirikizumab (LY3074828) in Healthy Participants

Healthy

United States
Pfizer

Terminated

A Study of Marstacimab to Compare Prefilled Pen (PFP) Device to Prefilled Syringe (PFS) Device

Healthy Volunteers

Belgium
University of Washington

Completed

A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula

Pancreatectomy; Hyperglycemia | Pancreatic Fistula | Pancreaticoduodenal; Fistula | Pancreatic Leak

United States
Universidade do Porto

Completed

Evaluation of Postoperative Pain With Eddy Tips (EPPET)

Pain, Postoperative

Portugal
University of Zurich
University Hospital, Geneva; University Hospital Inselspital, Berne; University... and other collaborators

Terminated

Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19

COVID-19 | Pulmonary Embolism, Deep Vein Thrombosis

Switzerland, Germany
Alvotech Swiss AG

Completed

PK, Safety and Tolerability Study of AVT02 (Adalimumab) Pre-filled Syringe (PFS) vs, AVT02 Autoinjector (AI)

Phase 1

New Zealand
AMAG Pharmaceuticals, Inc.

Terminated

Study Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal Women

Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) in Healthy Post-menopausal Women

United States
Novartis Pharmaceuticals

Completed

A Study Evaluating the Effectiveness of AMG 334 Injection in Preventing Migraines in Adults Having Failed Other Therapies

Episodic Migraine

Austria, Belgium, Italy, Spain, Germany, Sweden, Czechia, Netherlands, France, Denmark, Switzerland, United Kingdom, Greece, Finland, Australia, Norway
Bristol-Myers Squibb

Completed

Relative Levels of BMS-986036 in Blood Plasma in Healthy, Overweight, and Obese Participants Following Subcutaneous Administration Via Auto-injector Versus Pre-filled Syringe

Healthy Participants

United States
AbbVie

Completed

A Study to Evaluate the Bioavailability of Risankizumab in Pre-filled Syringe or Auto-injector in Healthy Adult Participants

Healthy Volunteers

United States
American University of Beirut Medical Center

Completed

Breastfeeding Success With the Use of the WHO Syringe Technique for Management of Inverted Nipples in Lactating Women

Breastfeeding | Inverted Nipple

Lebanon
University of Liege
Université Catholique de Louvain

Active, not recruiting

Treating Severe Brain-injured Patients With Apomorphine

Disorder of Consciousness

Belgium
Okan University

Completed

The Effect of Needle-free Injection System During Palatal Anesthesia

Pediatric Anesthesia | Local Anesthesia

Turkey
Hospital Universitari Vall d'Hebron Research Institute

Completed

Remifentanil Effect-site Prediction by Algometry

Conscious Sedation Failure During Procedure

Spain
Shire

Completed

Long-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS)

Short Bowel Syndrome

United States, Canada, Finland, Italy, United Kingdom, Belgium
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab 2 mL Auto-injector (300 mg) in Subjects With Moderate to Severe Plaque Psoriasis (MATURE)

Plaque Psoriasis

Spain, Germany, United States, Iceland, Canada, Poland
Novartis Pharmaceuticals

Completed

A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS Patients

Multiple Sclerosis

United States, Austria, Spain, Czechia, Estonia, Bulgaria, Latvia, Lithuania, Russian Federation
Regeneron Pharmaceuticals

Completed

Study to Evaluate an Aflibercept (EYLEA®) Prefilled Syringe

Chorioretinal Vascular Disease

United States
Janssen Research & Development, LLC

Completed

A Study of Intravenous Formulation of Guselkumab Using Prefilled Syringes and Final Vialed Product in Healthy Participants

Healthy

Germany
UCB Biopharma SRL

Terminated

A Study to Evaluate the Bioequivalence of Bimekizumab Given as 1x2mL or 2x1mL Subcutaneous Injection in Healthy Study Participants

Healthy Study Participants

Germany
University of Colorado, Denver
Sanofi

Completed

Comparison of SoloSTAR With a Syringe-administered Glargine Insulin in Diabetic Patients From the Hospital

Diabetes

United States
Pfizer

Terminated

A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome

Cystitis, Interstitial

Canada, United States, Spain, Belgium, Slovakia, Korea, Republic of, Finland, Hong Kong, Japan, Poland, Romania, Russian Federation, Sweden, Taiwan
Novartis Pharmaceuticals

Completed

Long-Term Safety and Tolerability of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patients

Acute Gouty Arthritis

Germany, United States, Lithuania, Canada
Zealand Pharma

Completed

A Bridging Trial to Compare the PK Profile When Glepaglutide is Administered Via Vial/Syringe Versus Autoinjector.

Healthy

Netherlands
Rawalpindi Medical College

Completed

Effect of Pretreatment of Lignocaine Versus Midazolam in Prevention of Etomidate Induced Myoclonus.

Myoclonic Jerk
Plovdiv Medical University

Completed

Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children

Pain Management | Local Anaesthesia

Bulgaria
Plovdiv Medical University

Completed

Efficacy of Virtual Reality in Reducing Injection Pain and Anxiety During Local Anesthesia in Children

Local Anesthesia | Injection Pain

Bulgaria
Fundacion Miguel Servet

Completed

Clinical Trial of the Use of Anakinra in Cytokine Storm Syndrome Secondary to Covid-19 (ANA-COVID-GEAS) (ANA-COVID-GEAS)

COVID-19 Pnemonia

Spain
Shire

Completed

Safety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Syndrome

Short Bowel Syndrome

Finland, Italy, United Kingdom, France
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site (ACHILLES)

Psoriatic Arthritis | Enthesitis | Axial Spondyloarthritis

Germany, Spain, United Kingdom, Greece, Bulgaria, Italy, Czechia, Slovakia
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder (ADAPT-2)

Methamphetamine Use Disorder

United States
University of Manchester

Terminated

SCIL-1Ra in COVID-19 Feasibility & PK/PD (SCIL_COV19)

COVID-19

United Kingdom
JW Pharmaceutical

Completed

A Study to Evaluate Efficacy and Safety of JTZ-951 Compared to Darbepoetin Alfa in Korean Renal Anemia Patients Receiving Hemodialysis.

Anemia of Chronic Kidney Disease

Korea, Republic of
Boston University
National Institute on Drug Abuse (NIDA)

Withdrawn

Pre-exposure Prophylaxis (PrEP) for People Who Inject Drugs (PWID)

Intravenous Drug Abuse
Calo Psychiatric Center

Completed

Differences in Schizophrenia With One-month and 3-month Paliperidone Palmitate Treatment

Schizophrenics
Medical University of Vienna

Completed

A Study to Evaluate the Efficacy of Tocilizumab as a Remission-Induction and Glucocorticoid-Sparing Regimen in Subjects With New-Onset Polymyalgia Rheumatica (PMR- SPARE)

Polymyalgia Rheumatica

Austria
Celltrion

Completed

To Compare the Pharmacokinetics and Safety of the Auto-injector and Pre-filled Syringe of CT-P17

Healthy

United States
Novartis Pharmaceuticals

Completed

Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration

Neovascular Age Related Macular Degeneration

United States
Ataturk University

Completed

"Syringe Free" Long-Axis In-Plane vs. Short-Axis Out-of-Plane Approach for Central Venous Catheter Placement

Critical Illness | Catheter Complications

Turkey

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