Search clinical trials for: Homologous Recombinant Repair (HRR)-related Genes

Total 10095 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia and other conditions

United States
Memorial Sloan Kettering Cancer Center

Completed

Biological Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Ascension Genesys Hospital

Unknown

Comparison of Patient Perceived Pain and Satisfaction Between Lightweight and Heavyweight Mesh for Laparoscopic Inguinal Hernia Repair

Inguinal Hernia

United States
Ascension Genesys Hospital

Unknown

Study Comparing Patient Function and Satisfaction With Arthroscopic Subacromial Decompression Before and After Repair of Complete Rotator Cuff Tears

Rotator Cuff Tear | Acromial Spur

United States
Tel-Aviv Sourasky Medical Center

Unknown

Pain Relief Following Arthroscopic Rotator Cuff Repair: Perioperative Pregabalin Administration Versus Interscalene Brachial Plexus Block

Pain

Israel
Genesis Center for Fertility & Human Pre-Implantation...

Unknown

Recombinant Versus Highly Purified FSH in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

Cyprus
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

DNA Repair Genes and Outcomes in Patients With Stage III NSCLC

Carcinoma, Non-Small-Cell Lung | Chemotherapy

Taiwan
University Hospital, Basel, Switzerland

Completed

Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma

Melanoma

Switzerland
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Severe Combined Immunodeficiency

United States
Targeted Genetics Corporation
Cystic Fibrosis Foundation

Terminated

Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis

Cystic Fibrosis

United States
IRCCS San Raffaele
Fondazione Telethon

Completed

Gene Therapy for ADA-SCID

Severe Combined Immunodeficiency Syndrome
Tissue Repair Company

Completed

Gene Therapy to Improve Wound Healing in Patients With Diabetes

Wounds and Injuries | Diabetes | Diabetic Foot Ulcers | Foot Wounds

United States
Genesys
Novo Nordisk A/S

Completed

The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit

Sepsis | Respiratory Failure | Renal Failure | Surgical Site Infection

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Descriptive Study of Recombinant Human Insulin-Like Growth Factor for Osteoporosis in Werner's Syndrome

Werner's Syndrome
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec and Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared With Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Effect of Recombinant Human Brain Natriuretic Peptide on Ventricular Remodeling and Cardiac Function in Patients With Acute Anterior Myocardial Infraction Undergoing Percutaneous Coronary Intervention

Ventricular Remodeling | Myocardial Infarction, Anterior Wall

China
Samsun University

Recruiting

The Impact of the Anaesthetic Technique Employed on the Quality of Recovery in Patients Undergoing Hysterectomy Surgery.

Analgesia | Acute Pain | Anesthesia

Turkey
Duke Street Bio Ltd

Not yet recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Advanced Malignancies With Homologous Recombination Deficiency (HRD) (Breast, Ovarian, mCRPC, Brain Metastases)
University Hospital Heidelberg

Not yet recruiting

Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor (PAMSARC)

Synovial Sarcoma | Desmoplastic Small Round Cell Tumor

Germany
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

SUperior Hypogastric Plexus Block During Laparoscopic hysterEctomy (SUBTLE) (SUBTLE)

Hysterectomy
Fujian Cancer Hospital
Zhangzhou Municipal Hospital of Fujian Province

Recruiting

Efficacy and Safety of AK104 Combined With Chemotherapy and Recombinant Human Adenovirus 5 Injection in Cervical Cancer

Cervical Cancer Recurrent

China
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase I Clinical Trial to Evaluate the Safety of 15-valent HPV Vaccine in Healthy Chinese People Aged 18-45 Years

HPV Infection | HPV-Related Carcinoma | Genital Wart | HPV-Related Intraepithelial Neoplasia

China
Verve Therapeutics, Inc.

Not yet recruiting

Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia

Hypercholesterolemia
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Bioequivalence Study of Two Different Dosage Form of Genakumab

Gouty Arthritis (GA)

China
Bayer

Not yet recruiting

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2) (SOHO-02)

Advanced Non-small Cell Lung Cancer | HER2 Mutation

United States, Korea, Republic of, Belgium, China, Hong Kong, Japan, Taiwan, Denmark, Germany, Israel, Poland, Italy, United Kingdom, Bulgaria, Czechia, Portugal, Switzerland, Greece, Turkey, Romania, Sweden, France, Singapore, Mexico, ... and more
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair (HERNIIA-2)

Inguinal Hernia

Netherlands
Assaf-Harofeh Medical Center

Not yet recruiting

Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery

Scoliosis

Israel
Medtronic - MITG

Not yet recruiting

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia (RECOVER)

Hernia | Hernia, Abdominal | Hernia, Ventral | Hernia Abdominal Wall
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.

Breast Cancer Subjects

China
MAXVAX Biotechnology Limited Liability Company

Not yet recruiting

Efficacy, Safety and Immunogenicity Study of Recombinant Zoster Vaccine(CHO Cell) in Adults Aged 40 Years and Older

Herpes Zoster

China
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Bilecik Seyh Edebali Universitesi

Not yet recruiting

The Effect of Mindfulness Training on Postoperative Pain - A Solomon Four Group Design

Postoperative Pain | Mindfulness Training | Inguinal Hernia Repair

Turkey
D. Bradley Welling, MD, PhD
Nobelpharma

Not yet recruiting

In-office Repair of Chronic Tympanic Membrane Perforations

Chronic Tympanic Membrane Perforation

United States
Ascidian Therapeutics, Inc

Recruiting

Prescreening Study to Identify Potential Participants for ACDN-01 Clinical Trials

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Weill Medical College of Cornell University
Intuitive Surgical

Not yet recruiting

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

Hiatal Hernia

United States
Jiaxing Pharmadax Genesis Pharmaceutical Technology...

Not yet recruiting

Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers

Solid Tumor
University Hospital, Angers

Not yet recruiting

Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD (FibroTG-HD)

Huntington Disease

France
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
Teva takeda

Not yet recruiting

A Survey of Recombinant ADAMTS13 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Thrombotic Thrombocytopenic Purpura (TTP)
Shandong University

Not yet recruiting

A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin

CTIT-Chemotherapy Induced Thrombocytopenia
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes (OPTION-DDR)

Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer
National Taiwan University Hospital

Recruiting

Reinterventions of Thoracic Endovascular Aortic Repair: a Retrospective Multicenter Cohort Study

Thoracic Endovascular Aortic Repair

Taiwan
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
The Second Hospital of Nanjing Medical University

Recruiting

Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD

Type A Aortic Dissection

China
Enloe Health
Robert A. Winn Diversity in Clinical Trials Award Program

Not yet recruiting

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention (GENESIS)

Solid Tumor, Adult
Hospital Universitari Vall d'Hebron Research Institute
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital and other collaborators

Recruiting

Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.

Hepatocellular Carcinoma | Portal Hypertension | Advanced Chronic Liver Disease

Spain
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Ovarian Cancer

United States, Germany

Search clinical trials for: Homologous Recombinant Repair (HRR)-related Genes

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