Search clinical trials for: Moderate to severe mouth pain

Total 479245 results

Taiwan Mundipharma Pharmaceuticals Ltd.

Unknown

Effect of Good Pain Management (GPM) Ward Program on Moderate to Severe Cancer Pain Patients (GPM)

Pain | Cancer

Taiwan
ProCore Ltd.

Completed

A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis

Osteoarthritis

Israel
Mallinckrodt

Withdrawn

Pharmacokinetics and Safety of MNK-155 in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain

Acute Pain

United States
Pfizer

Completed

A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain

Low Back Pain | Chronic Pain | Analgesia

United States
AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Open-Label Trial to Evaluate the Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg in Patients With Post-Operative Pain

Acute Moderate-to-severe Pain

United States
Mundipharma Korea Ltd

Completed

An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)

Chronic Pain

Korea, Republic of
Novartis Pharmaceuticals

Completed

Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib

Pain

United States
University Hospital Inselspital, Berne
Aalborg University

Completed

Capsaicin-induced Muscle Pain in Humans

Healthy

Switzerland
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; Intensive Care National...

Completed

FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study (FIRST-ABC)

Hypoxia | Respiratory Acidosis | Moderate/Severe Respiratory Distress

United Kingdom
Centrexion Therapeutics

Completed

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Osteoarthritis of the Knee

United States
Pfizer

Completed

Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer Pain

Chronic Noncancer Pain

United States
Charleston Laboratories, Inc

Completed

A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip

Pain | Nausea | Vomiting

United States
Charleston Laboratories, Inc

Completed

Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain

Pain | Nausea | Vomiting

United States
Joseph Hazelton

Completed

A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)

Pain | Nausea | Vomiting

United States
Mallinckrodt

Completed

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

Pain, Postoperative | Bunion

United States
Daewon Pharmaceutical Co., Ltd.

Completed

Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery

Acute Toothache Patients Above Moderate Pain After Teeth Extraction Surgery
Mundipharma Pte Ltd.
Mundipharma Korea Ltd; Mundipharma (Hong Kong) Ltd; Mundipharma Distribution...

Completed

Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain

Osteoarthritis | Rheumatoid Arthritis | Lower Back Pain | Joint Pain | Muscle Pain

Hong Kong, Korea, Republic of, Philippines
Norwegian University of Science and Technology

Completed

Respiratory Treatment of Patients With Moderate and Severe Traumatic Brain Injury

Traumatic Brain Injury

Norway
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain

Low Back Pain | Low Back Pain, Recurrent

United States, Belgium, Canada, Netherlands
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)

Pain | Mononeuropathies | Neuralgia | Neuralgia, Postherpetic

United States, Spain, Belgium, Netherlands
Shanghai Jiao Tong University School of Medicine

Unknown

Efficacy and Mechanism Study of Bariatric Surgery to Treat Moderate to Severe Obesity in Han Chinese Population

Morbid Obesity

China
Menarini Group

Completed

Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID lap)

Acute Pain

Romania, Poland, Hungary, Latvia, Lithuania, Russian Federation, Slovakia, Spain
Neil Singla
Mallinckrodt

Terminated

A Randomized, Open Label, Prospective Study to Explore the Clinical Characteristics of Oral MNK155 and Norco 7.5mg/325 When Used for the Treatment of Moderate to Severe Post Operative Pain

Post Operative Pain

United States
Menarini Group

Completed

Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID-art)

Acute Pain

Serbia, Latvia, Spain, Hungary, Lithuania, Poland, Taiwan, Czech Republic, Germany, Ukraine
Antonios Likourezos

Completed

Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department

Pain

United States
KLOX Technologies Inc.

Completed

Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis

Moderate to Severe Chronic Periodontitis

Canada
Purdue Pharma LP

Withdrawn

Pharmacokinetics, Safety, and Efficacy of Intravenous Dosing of Buprenorphine in Pediatric Patients Who Require Opioid Analgesia for Acute Moderate to Severe Pain

Other Acute Postoperative Pain | Prolonged Endotracheal Intubation
Janssen Research & Development, LLC

Completed

A Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Cancer-related Pain

Pain, Radiating | Pain, Burning | Pain, Crushing | Pain, Migratory | Pain, Splitting

United States, France, Spain, Poland, Portugal
Mario Negri Institute for Pharmacological Research

Completed

RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder. (CERP)

Cancer | Cancer Pain

Italy
Janssen Pharmaceutica

Withdrawn

A Safety and Effectiveness Study of Prolonged Release Tapentadol Hydrochloride Among Filipino Patients With Moderate to Severe Chronic Non-Cancer Pain

Moderate to Severe Chronic Non-cancer Pain
Purdue Pharma LP

Completed

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Janssen Pharmaceutica

Withdrawn

A Safety and Effectiveness Study of Immediate Release Tapentadol Hydrochloride Among Filipino Patients With Moderate to Severe Acute Non-Cancer Pain

Moderate to Severe Acute Non-Cancer Pain
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine Surgery

Postoperative Pain | Chlorzoxazone

Denmark
Purdue Pharma LP

Completed

Long-Term Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children Who Completed OTR3001

Pain

United States, Israel
Pain Therapeutics

Completed

Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers

Healthy

United States
Pain Therapeutics

Completed

Pharmacokinetics And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers

Healthy

United States
Francisco Campos-Rodriguez
Sociedad Española de Neumología y Cirugía Torácica; Fondo de Investigacion...

Completed

Effect of CPAP Treatment in Women With Moderate-to-severe OSA.

Obstructive Sleep Apnea

Spain
Kythera Biopharmaceuticals

Completed

Patient Experience Study of Deoxycholic Acid Injection

Moderate or Severe Submental Fullness

United States
Goethe University

Completed

Activated MMP-8 as Diagnostic Test for Periodontitis (MMP-8)

Generalized Chronic Periodontitis
Merck Sharp & Dohme LLC

Withdrawn

Safety and Efficacy Study of an Etoricoxib and Tizanidine Fixed Dose Combination in Participants With Moderate to Severe Acute Low Back Pain (MK-0663B-164)

Low Back Pain
Lake Erie Research Institute

Completed

RESTIFFIC™ Foot Wrap Reduces Moderate to Severe Restless Leg Syndrome (RESTIFFIC)

Restless Leg Syndrome

United States
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Wayne State University
Abbott

Terminated

Addition of Modulators of Homocysteine to Adalimumab Therapy in the Treatment of Moderate to Severe Plaque Psoriasis

Psoriasis
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Government Dental College and Research Institute...

Completed

1% Metformin in Moderate and Severe Periodontitis

Periodontitis
Olatec Therapeutics LLC

Completed

Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee

Osteoarthritis of the Knee

United States
Wex Pharmaceuticals Inc.

Completed

Safety & Efficacy Study of Subcutaneous Tetrodotoxin for Moderate to Severe Inadequately Controlled Cancer-related Pain (TEC-006)

Pain | Cancer

Canada
Amneal Pharmaceuticals, LLC
Symbio, LLC

Completed

Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)

Uncomplicated Urinary Tract Infections

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)

Pain | Postherpetic Neuralgia

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain

Pain | Osteoarthritis | Low Back Pain

United States, Australia, Canada, New Zealand

3

Subscribe