Search clinical trials for: Phase I

Total 492414 results

M.D. Anderson Cancer Center
Active Biotech AB

Not yet recruiting

Open Label Phase 2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-Essential Thrombocytosis Myelofibrosis

United States
Helen Keller International
Eleanor Crook Foundation

Not yet recruiting

Maternal Adherence to MMS in Nepal (NAMASTE MMS)

Pregnancy Related | Supplementation | Postnatal Related
Amsterdam UMC, location VUmc
Dutch Kidney Foundation; B.Braun Avitum AG; Niercentrum aan de Amstel

Not yet recruiting

The Microcirculation, Dialysis Modality and Sequestered Salt (MIMOSA)

End-stage Renal Disease
European Organisation for Research and Treatment...
Novartis

Not yet recruiting

177Lu-DOTATATE for Recurrent Meningioma (LUMEN-1)

Recurrent Meningioma
Riphah International University

Recruiting

Muscle Energy Technique of Lower Limb Muscles in Forward Head Posture

Forward Head Posture

Pakistan
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

CAPABLE Transplant

Depression | Quality of Life | End Stage Renal Disease | Disability Physical

United States
European Institute of Oncology

Recruiting

What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials

Solid Tumor

Italy
Reveal Pharmaceuticals Inc.
National Cancer Institute (NCI)

Recruiting

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

Central Nervous System (CNS) Lesions

United States
Virginia Commonwealth University
Organization for Autism Research

Recruiting

Improving Access to Community-Based Occupations Via a Rideshare Training Program

Autism

United States
Visirna Therapeutics HK Limited

Not yet recruiting

A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients

Nash
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Study Evaluating the Feasibility of an Adapted Physical Activity Program During the Hospitalization Phase in Cancer Patients Undergoing Treatment (PREVAPA)

Cancer
Riphah International University

Recruiting

Effects of Lower Limb Resistance Band Exercises in Phase 1 Cardiac Rehabilitation

Cardiovascular Diseases

Pakistan
The Fourth Affiliated Hospital of Zhejiang University...

Not yet recruiting

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

Postoperative Pain
Vrije Universiteit Brussel
University Ghent; Research Foundation Flanders

Not yet recruiting

Muscular Changes in the First 12 Weeks After Stroke. (StrIMuC12)

Stroke
Rion Inc.
Professional Education and Research Institute

Recruiting

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

Diabetic Foot Ulcer

United States
University of Oxford
Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston...

Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Malaria,Falciparum

United Kingdom
Celgene

Not yet recruiting

A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment

Renal Impairment

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis (LEAKDYN)

Aortic Diseases

France
Dana-Farber Cancer Institute
ImmunityBio, Inc.; Kidney Cancer Association

Not yet recruiting

A Phase 0 Pilot Study of Memory-like Natural Killer (NK) Cell Immune Therapy in Combination With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

Renal Cell Carcinoma | Urothelial Carcinoma | Renal Carcinoma

United States
M.D. Anderson Cancer Center

Not yet recruiting

Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer

Triple Negative Breast Cancer | Stage 1 cT1b-T1cN0M0

United States
UCB Biopharma SRL

Not yet recruiting

A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

Childhood Absence Epilepsy | Juvenile Absence Epilepsy
UCB Biopharma SRL

Not yet recruiting

A Study to Assess the Safety and Pharmacokinetics of a Single Dose of UCB9741 in Healthy Caucasian and Japanese Participants

Healthy Participants
Beijing Friendship Hospital
Changhai Hospital; The First Affiliated Hospital of Anhui Medical University; Fudan University and other collaborators

Recruiting

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer: From a Multicenter Phase II Cohort to a Phase III Randomized Controlled Study

Locally Advanced Rectal Carcinoma

China
Tianjin Hemay Pharmaceutical Co., Ltd

Recruiting

A Phase Ⅲ Study of Hemay022 in Combination With AI In Advanced Breast Cancer

Breast Cancer

China
The University of Hong Kong-Shenzhen Hospital

Not yet recruiting

iTAPVR Study - Phase II Randomized Study

Advanced Tumors
Amgen

Recruiting

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Sjogren's Syndrome

United States
Suzhou Genhouse Bio Co., Ltd.
Shanghai East Hospital; Shandong Tumor Hospital

Recruiting

A Phase I/II Clinical Study to Evaluate The Safety, PK, PD of GH55 in Patients With MAPK Mutant Advanced Solid Tumors

Advanced Solid Tumors With MAPK Signal Pathway Mutant

China
UCB Biopharma SRL

Recruiting

A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Japanese Male Study Participants

Healthy Study Participants

Japan
University of Pennsylvania

Not yet recruiting

Light Therapy in End Stage Kidney Disease

End Stage Renal Disease
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation Phase I Clinical Study to Assess the Safety, Pharmacokinetics, and Immunogenicity of HLX6018 in Healthy Subjects

IPF
Zhejiang Cancer Hospital

Not yet recruiting

Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial

Metastatic Breast Cancer

China
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects

EGFR Overexpression
HC Biopharma Inc.

Recruiting

A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
M.D. Anderson Cancer Center
Novartis Pharmaceuticals

Not yet recruiting

Phase II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Philadelphia Chromosome-Positive

United States
Zhejiang Haichang Biotech Co., Ltd.

Not yet recruiting

Phase 2 Study of WGI-0301 in Combination With Sorafenib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)
M.D. Anderson Cancer Center
Elevar Therapeutics

Not yet recruiting

A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma

Metastatic Olfactory Neuroblastoma | Recurrent Olfactory Neuroblastoma

United States
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase Ib/II Clinical Study of HRS-1167 in Combination With Bevacizumab in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Instituto Valenciano de Infertilidade de Lisboa
Gedeon Richter Ltd.

Recruiting

Assessing the Convenience of Natural Proliferative Phase Frozen Embryo Transfer

Frozen Embryo Transfer

Portugal
Arab Contractors Medical Centre

Not yet recruiting

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy (BASiC-CIC)

Chemotherapy Induced Systolic Dysfunction

Egypt
InnovaGyn, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Phase II Study of Ovulation in Obese Women

Pregnancy Prevention

United States
Instituto de Investigación Hospital Universitario...

Not yet recruiting

Assessing Interest in Web/App Platforms for Early Phase Clinical Trial Recruitment

Assessing Interest in a Platform for Early Phase Clinical Trial Recruitment
Oslo University Hospital
University of Oslo; Sunnaas Rehabilitation Hospital; South-Eastern Norway Regional...

Recruiting

Effectiveness of a Self-management Program After Traumatic Injury (SEMPO)

Trauma Injury | Trauma, Multiple | Polytrauma

Norway
International Agency for Research on Cancer
Centre Leon Berard

Not yet recruiting

Virtual RealiTy and mUsic in the Oncology SEtting - Phase 1 (VRtuose1)

Breast Cancer

France
Suzhou Genhouse Bio Co., Ltd.

Recruiting

A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC

Non-Small Cell Lung Cancer With EGFR Mutation

China
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Merck Sharp & Dohme LLC

Not yet recruiting

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) and Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

Non-small Cell Lung Cancer (NSCLC)
Hospices Civils de Lyon

Not yet recruiting

Early-phase Telecare Programs for Minor Stroke (COGaDOM)

Minor Stroke

France
Guangzhou FineImmune Biotechnology Co., LTD.

Recruiting

Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors (TAL-T)

Advanced Solid Tumor | Immunotherapy | Tumor Associated Lymph Node T Cell

China
N.N. Petrov National Medical Research Center of...

Recruiting

Stereotactic Radiation Therapy for HE2-positive Oligometastatic Breast Cancer

Oligometastatic Disease | HER2-positive Metastatic Breast Cancer

Russian Federation

3

Subscribe