Search clinical trials for: Phenotype

Total 798 results

Michael J. Fox Foundation for Parkinson's Research
Institute for Neurodegenerative Disorders

Recruiting

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort (PPMI)

Parkinson Disease

United States, Canada, Spain, Israel, Austria, Germany, Greece, Italy, Netherlands, Nigeria, United Kingdom, Luxembourg
Chelsea and Westminster NHS Foundation Trust

Recruiting

PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs (PHENOTYPE)

COVID-19 | Corona Virus Infection | Coronavirus | 2019 Novel Coronavirus Infection | 2019nCoV

United Kingdom
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital of Anhui Medical University; Henan Cancer Hospital and other collaborators

Recruiting

Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients

Induction Chemotherapy | Acute T-Lymphocytic Leukemia | T-cell Lymphoblastic Lymphoma Leukemia | T-cell/Myeloid Mixed Phenotype Acute Leukemia

China
Balgrist University Hospital
University of Zurich

Recruiting

Back Pain - Linking Phenotype to Pain Mechanism and Outcome.

Low Back Pain

Switzerland
Arkansas Children's Hospital Research Institute

Recruiting

Mitochondria (MI) Energy - Linking Bioenergetic Phenotypes in Circulating Cells With Cardiometabolic Health in School-age Children

Healthy

United States
The Institute of Molecular and Translational Medicine...

Recruiting

Assesment of Multiomics Profiles in Health and Disease. (ENIGMA)

Genetic Predisposition to Disease

Czechia
National Human Genome Research Institute (NHGRI)

Recruiting

Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity During the COVID19 Pandemic

Mitochondrial Disease

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Immunodeficiency

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic Syndrome | Refractory Mixed Phenotype Acute Leukemia | Refractory Acute Leukemia... and other conditions

United States
Dr. Rebecca Schule
German Research Foundation; German Center for Neurodegenerative Diseases (DZNE)

Recruiting

Phenotypes, Biomarkers and Pathophysiology in Spastic Ataxias (SPAX-PBP)

Spastic Ataxia

Canada, France, Germany, Italy, Netherlands, Turkey, United Kingdom
Sheba Medical Center

Recruiting

CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expression

Acute Myeloid Leukemia

Israel
Fred Hutchinson Cancer Center
medac GmbH

Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States
Luca Sangiorgi

Recruiting

Registry of Ollier Disease and Maffucci Syndrome (ROM)

Ollier Disease | Maffucci Syndrome

Italy
Luca Sangiorgi

Recruiting

Registry of Multiple Osteonchodromas (REM)

Multiple Osteochondroma

Italy
Luca Sangiorgi

Recruiting

Registry of Ehlers-Danlos Syndrome (RED)

Ehlers-Danlos Syndrome

Italy
M.D. Anderson Cancer Center

Recruiting

Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting

Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Acute Bilineal Leukemia | Acute Biphenotypic Leukemia | T Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
Luca Sangiorgi

Recruiting

Registry of Osteogenesis Imperfecta (ROI)

Osteogenesis Imperfecta

Italy
University Medical Center Groningen
Dutch Cancer Society

Recruiting

Senescence and the Early Ageing Phenotype After Chemotherapy for Testicular Cancer: the SEA-CAT Study

Testicular Cancer

Netherlands
Kura Oncology, Inc.

Recruiting

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Leukemia of Ambiguous Lineage | Advanced Malignant Neoplasm | Mixed Phenotype Acute Leukemia | Mixed Lineage Leukemia | Mixed Lineage Acute Leukemia

United States, Spain, United Kingdom, France, Germany, Canada, Belgium, Italy
Syndax Pharmaceuticals

Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage | Mixed Phenotype Acute Leukemia | Mixed Lineage Acute Leukemia

United States, Israel, Spain, Australia, Netherlands, Germany, Canada, France, Italy, Lithuania
University Hospital, Montpellier

Recruiting

Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy (DIAMYOTIT)

Genetic Disease | Myopathy | Phenotypic Abnormality

France
MejoraVisionMD
Maisonneuve-Rosemont Hospital; Retina and Genomics Institute

Recruiting

Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.

Retinitis Pigmentosa | Usher Syndromes | Cone Dystrophy | Retina; Dystrophy

Mexico
Dr. Rebecca Schule
German Federal Ministry of Education and Research; German Center for Neurodegenerative...

Recruiting

Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders (HSP-PBP)

Hereditary Spastic Paraplegia

Austria, Germany, Italy
Universita di Verona

Recruiting

Successful Aging and Frailty (SAFe)

Cognitive Impairment | Sarcopenia | Frailty Syndrome

Italy
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States, Canada, Australia, Puerto Rico, New Zealand
Institut Paoli-Calmettes
INATHERYS

Recruiting

Study of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute Leukemia (INA03)

Acute Lymphoblastic Leukemia, in Relapse | Acute Myeloid Leukemia, in Relapse | Mixed Phenotype Acute Leukemia | Acute Lymphoblastic Leukemia Recurrent | Acute Myeloid Leukaemia Recurrent

France
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); Duke University; National...

Recruiting

Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes (SANDIA)

Obesity | Asthma

United States
Chinese PLA General Hospital
Beijing Friendship Hospital; Guang'anmen Hospital of China Academy of Chinese... and other collaborators

Recruiting

Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy

Diabetic Kidney Disease

China
University College, London
NIHR Rare Diseases Translational Research Collaboration; Barts Cardiovascular...

Recruiting

The Deep Phenotype of Lamin A/C Cardiomyopathy

Lamin A/C Gene Mutation | Dilated Cardiomyopathy, Familial

United Kingdom
Johns Hopkins All Children's Hospital

Recruiting

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Mixed Phenotype Acute Leukemia

United States
Orca Biosystems, Inc.

Recruiting

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Mixed Phenotype Acute Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Acute Lymphoblastic Leukemia | Acute Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Acute Leukemia of Ambiguous Lineage | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia | Myelodysplastic Syndrome With Excess Blasts-1 | Mixed Phenotype Acute Leukemia | Blasts Under 5 Percent... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype

Glioma | Glioblastoma | Malignant Glioma | Low Grade Glioma | High Grage Glioma

United States
Tampere University Hospital

Recruiting

Small Airway Inflammation and Dysfunction in Different Asthma Phenotypes

Asthma

Finland
Jessa Hospital
Maastricht University Medical Center; UZA

Recruiting

Genotype-phenotype Correlation Study of Presymptomatic and Symptomatic DFNA9 Patients

Vestibular Diseases | DFNA9

Belgium
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

Sickle Cell | PKLR Variants | Adenosine Triphosphate Activities

United States
Abramson Cancer Center at Penn Medicine

Recruiting

Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

MDS | Leukemia, Acute

United States
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Prospective Analysis of "Genotype-phenotype" Correlations Observed in a Large Cohort of Patients With Hereditary Retinal Dystrophies - GEPHIRD (GEPHIRD)

Hereditary Retinal Dystrophies

France
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Vascular Disease Discovery Protocol

Genetic Predisposition | Vascular Dysfunction | Genetic Mutations

United States
University of Texas Southwestern Medical Center
Massachusetts General Hospital

Recruiting

Dystonia Genotype-Phenotype Correlation

Dystonia | Dystonia; Idiopathic | Dystonia, Primary | Dystonia, Secondary | Dystonia, Familial | Dystonia Disorder | Dystonias, Sporadic | Dystonia; Orofacial | Dystonia Lenticularis | Dystonia, Paroxysmal | Dystonia 6 | Dystonia 5 | Dystonia 8 | Dystonia 9 | Dystonia 19 | Dystonia 10 | Dystonia 11 | Dystonia 20 | Dystonia 12 | Dystonia... and other conditions

United States
Ciusss de L'Est de l'Île de Montréal

Recruiting

Correlation Between NOL Index After Stimulus and Post-operative Opioid, Pain, Pre-operative Phenotype

Pain, Postoperative | Anesthesia | Nociceptive Pain | Catastrophizing

Canada
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Rare Bleeding Disorders in the Netherlands (RBIN)

Rare Bleeding Disorders

Netherlands
Institut Pasteur

Recruiting

Pilot Study: Characterization of the Immune Phenotype of Patients Allergic to Wasp Venom or Penicillin (WasPenIP)

Allergy

France
Roncarolo, Maria Grazia, MD
National Cancer Institute (NCI)

Recruiting

Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders (T-allo10)

Hodgkin's Lymphoma | MDS (Myelodysplastic Syndrome) | ALL | Mixed Phenotype Acute Leukemia | AML - Acute Myeloid Leukemia | NHL - Non-Hodgkin's Lymphoma

United States
Children's Oncology Group
National Cancer Institute (NCI); EsPhALL Network/ BFM Study Group

Recruiting

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | T Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States, Canada, Puerto Rico, Australia, Finland, New Zealand, Saudi Arabia, Germany, Austria, Belgium, Chile, Czechia, France, Italy, Netherlands, Sweden, Switzerland, Hong Kong, Israel
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation (SILOG)

Limbus Corneae

France
National Center for Complementary and Integrative...

Recruiting

Clinical and Scientific Assessment of Pain and Painful Disorders

Pain | Normal Physiology

United States
National Institute of Diabetes and Digestive and...

Recruiting

Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism

Brown Adipose Tissue (BAT) Physiology | Phenotyping | Brown Adipocytes

United States
Imagine Institute

Recruiting

Characterization of Phenotype and Genotype of Early Onset Enteropathies (IMMUNOBIOTA)

Inflammatory Bowel Disease

France
Abramson Cancer Center at Penn Medicine

Recruiting

Breast Cancer 2-PREVENT Translational Center of Excellence (TCE) - Metastatic Markers of Recurrent Tumor Phenotype for Breast Cancer

Women With Suspected or Confirmed Recurrent Breast Cancer

United States

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