Search clinical trials for: Plasma Concentration

Total 8748 results

Odense University Hospital
Novartis; Danish Research Agency

Completed

Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine.

Metabolic Clearance Rate

Denmark
Centre Hospitalier Universitaire de Nīmes

Completed

Reproducibility of Plasma Nucleosomes and Free DNA as Markers for Venous Thromboembolism

Venous Thromboembolism

France
Oslo University Hospital

Completed

Meropenem Plasma Concentration Measurements at the Pediatric Medical Ward, Oslo University Hospital, Rikshospitalet

Bacterial Infection

Norway
Oregon Health and Science University

Terminated

Moderate Intensity Exercise and Phenylketonuria

Phenylketonuria | PKU

United States
Laval University

Completed

Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial Hypercholesterolemia

Familial Hypercholesterolemia

Canada
Pfizer

Completed

A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06372865 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)

Healthy

Belgium
Canadian Immunodeficiency Research Collaborative

Completed

Concentrations of Raltegravir in the Semen of HIV-Infected Men

HIV

Canada
Mahidol University

Completed

Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty

Total Knee Arthroplasty | Serum Bupivacaine Level | Periarticular Block

Thailand
Pfizer

Completed

A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)

Healthy

Belgium
Janssen-Cilag G.m.b.H

Terminated

A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls

Schizophrenia

Germany
Astellas Pharma Inc

Completed

A Study to Compare the Oral Absorption of ASP1941 Among Two Types of Tablets

Healthy | Plasma Concentration of ASP1941

Japan
University Hospital, Clermont-Ferrand

Unknown

Pharmacokinetic Study of 48-hour Sevoflurane Inhalation Using a Disposable Delivery System (AnaConDa©) in ICU Patients With Acute Kidney Injury (SEVOKID)

Acute Kidney Injury

France
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
TNO
Alloksys Life Sciences B.V.

Completed

Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)

Healthy

Netherlands
Astellas Pharma Inc

Completed

Post-marketing Study to Evaluate the Effect of Mirabegron on the Plasma Concentration of Tolterodine

Healthy | Pharmacokinetics of Mirabegron and Tolterodine

Japan
Universidad del Desarrollo

Completed

Neuronal Inertia in Propofol Anesthesia (INERTIA)

General Anesthesia | Propofol Pharmacodynamics | Propofol Target Controlled Infusion | Loss of Consciousness and Recovery of Consciousness | Propofol Plasma Concentration

Chile
Fonterra Research Centre
Changi General Hospital

Completed

Micronutrient-supplemented Milk Study in Women of Childbearing Age

Increase the Concentration of Folic Acid in Women of Childbearing Age

Singapore
Cephalon

Completed

Study of the Efficacy and Multiple-Dose Plasma Concentration-Time Profiles of Armodafinil and PROVIGIL

Chronic Shift Work Sleep Disorder

United States
Astellas Pharma Inc

Completed

Multiple Oral Administration of ASP7991 to Non-elderly Male Subjects

Healthy | Pharmacokinetics of ASP7991

Japan
Janssen Research & Development, LLC

Completed

A Study to Compare Capillary and Venous Whole Blood and Plasma Concentrations of Five Antipsychotics

Healthy

Belgium
Pfizer

Completed

A Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Multiple Oral Doses Of PF-04895162

Healthy

United States
University Hospital, Linkoeping

Completed

Pharmacogenetics of Propofol and Depth of Anesthesia

Anesthesia | Propofol

Sweden
Astellas Pharma Inc

Completed

A Study to Evaluate Absorption, Distribution and Elimination of Mirabegron After Oral Administration to Non-elderly Healthy Chinese Subjects

Healthy Subjects | Plasma Concentration of Mirabegron

Japan
Astellas Pharma China, Inc.

Completed

Study to Assess the Safety and Plasma Concentration of YM178 OCAS Tablet (Mirabegron) in Healthy Chinese Volunteers

Healthy Chinese Volunteers

China
Lundbeck LLC

Withdrawn

An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile Spasms

Infantile Spasms
Purdue Pharma LP

Completed

Examine Plasma Concentrations of Buprenorphine Following Reapplication of Buprenorphine Transdermal System (BTDS) After Variable Application Site Rest Periods

Healthy

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Pharmacological Effect and Plasma Concentration of ASP7991 After Single Oral Administration to Healthy Volunteers

Healthy | Pharmacokinetics of ASP7991

Japan
Novartis Pharmaceuticals

Completed

Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure (ESCAPE-SHF)

Heart Failure

Russian Federation, Germany, Poland
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Oral Doses Of PF-06273340

PAIN

Belgium
Seoul National University Bundang Hospital

Unknown

Concentration of S-1 Metabolites in Tear and Plasma of Patients Receiving TS-1

Gastric Cancer

Korea, Republic of
Pontificia Universidad Catolica de Chile

Completed

Plasma Concentrations of Levobupivacaine With and Without Epinephrine in Transversus Abdominis Plane Blocks

Transversus Abdominis Plane Block

Chile
GlaxoSmithKline

Completed

At What Time Therapeutic Plasma Concentrations of Paracetamol Are Achieved in Two Marketed Formulations

Healthy Volunteer

United Kingdom
Vanderbilt University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Selenium Supplementation of Patients With Cirrhosis

Cirrhosis

United States
University Hospital, Clermont-Ferrand
Unither Pharmaceuticals

Completed

Pilot Study of Pharmacology of Paracetamol Administered Per-oral Mucosa (PMB)

Healthy
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of YM150 on the Plasma Concentration of Digoxin in Healthy Subjects

Healthy | Pharmacokinetic of Digoxin

France
Astellas Pharma Inc

Completed

A Study to Investigate the Plasma Concentration of YM150 After Repeated Administration to Elderly Subjects

Healthy Elderly Subject | Pharmacokinetic of YM150

Japan
IRCCS Policlinico S. Matteo

Completed

Assessment of Systemic Pharmacokinetics of Levobupivacaine and Ropivacaine During Continuous Epidural Infusion (LEVOROPI)

Surgery | Anesthesia

Italy
University of Manitoba

Completed

Efficacy of Plant Sterol-Fortified Dairy Product on Plasma Lipid and Plant Sterol Concentrations in Humans

Hypercholesterolemia

Canada
Center for Health, Exercise and Sport Sciences,...

Completed

The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers

Hyperhomocysteinemia

Serbia
Astellas Pharma Inc

Completed

A Study to Assess the Effect of ASP1941 and Mitiglinide on Their Plasma Concentration

Healthy | Pharmacokinetics of ASP1941 | Pharmacokinetics of Mitiglinide

Japan
Astellas Pharma Inc

Completed

A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet and Conventional Tablet Under With Water Intake

Healthy | Plasma Concentration of YM060

Japan
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.

Pharmacokinetics | Safety | Phase 1 | Single Dose | Toleration

Belgium
Astellas Pharma Inc

Completed

A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet (Without Water) and Conventional Tablet

Healthy | Plasma Concentration of YM060

Japan
University Medical Center Groningen

Completed

Influence of Intracranial Lesions on Bispectral Index

Supratentorial Brain Tumor

Netherlands
Xijing Hospital

Unknown

Plasma Adiponectin Concentration, Activity and Isoforms in Newly Diagnosed and Untreated Type 2 Diabetes Mellitus

Diabetes Mellitus

China
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Plasma Concentrations, Metabolism and Excretion of 14C-paliperidone After a Single Oral Dose

Schizophrenia
University Hospital, Bordeaux

Completed

Saliva and Plasma Endocannabinoids Concentrations According to Feeding Status and Body Mass Index (SALIVENDO)

Obesity

France
Hospitales Universitarios Virgen del Rocío

Completed

Plasma and Intracellular Concentrations of Raltegravir and Etravirine Administered Once Daily (RAET)

HIV Infections | HIV-1 Infection

Spain
AstraZeneca

Completed

Investigation Into the Correlation of Plasma Hs-CRP Concentrations and Cardiovascular Risk in Korean Population (CALLISTO)

hsCRP

Korea, Republic of
University of Zurich
Ixodes GmbH; Appletree AG

Completed

Safety, Skin and Plasma Concentration of Azithromycin Dermal Formulation (IXO-01)

Lyme Disease

Switzerland

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