Search clinical trials for: Primaquine double dose (PQdd)

Total 25444 results

University of Vermont

Completed

Evaluation of Safety, Reactogenicity and Immunogenicity of Fractional-dose Inactivated Polio Vaccine (fIPV) Given Intradermally With Double Mutant Enterotoxigenic Escherichia Coli Heat Labile Toxin (dmLT) Adjuvant

Polio

United States
The HIV Netherlands Australia Thailand Research...
Ministry of Education, Thailand

Completed

Efficacy and Safety of Single Versus Double Ritonavir-boosted Protease Inhibitor (PI)-Based Antiretroviral Therapy (ART) Regimens

HIV Infections | HIV Infection

Thailand
Oman Medical Speciality Board

Unknown

Double Dose Magnesium Sulphate in Moderate-severe Asthma in Paediatrics

Asthma in Children
GlycoMimetics Incorporated

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Rivipansel With rHuPH20 in Healthy Subjects

Healthy

Belgium
Bristol-Myers Squibb

Completed

Single and Multiple Dose Pharmacokinetics of BMS-986165 in a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Chinese Subjects

Autoimmune Diseases

China
Eleusis Therapeutics

Completed

A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

Healthy Volunteers
Perosphere Pharmaceuticals Inc, a wholly owned...

Completed

Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban (PER977-P1)

Anticoagulant Reversal | Reversal of Edoxaban Induced Anticoagulation

United States
AbbVie

Completed

Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Australia, Belgium, Canada, Czechia, France, Hungary, Korea, Republic of, Netherlands, Romania, Russian Federation, Spain
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Unknown

Randomized, Double Blinded, Placebo Controlled, Single Dose Escalation Study of 608 in Healthy Subjects

Moderate to Severe Plaque Psoriasis

China
First Affiliated Hospital Xi'an Jiaotong University
Fudan University; Yangtze River Pharmaceutical Group Co., Ltd.

Unknown

A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients

Coronary Artery Disease

China
University of Lausanne Hospitals

Completed

Immunogenicity and Safety of the Seasonal Flu Vaccine in Elderly and in SOT Recipients

Healthy Volunteers

Switzerland
Singapore General Hospital
Duke-NUS Graduate Medical School; 60 Degrees Pharmaceuticals LLC

Withdrawn

Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore

Dengue Fever

Singapore
Sunnybrook Health Sciences Centre
Peel Regional Paramedic Service; Toronto Paramedic Services; Halton Region Paramedic... and other collaborators

Completed

DOuble SEquential External Defibrillation for Refractory VF Pilot Study (DOSE-VF)

Ventricular Fibrillation

Canada
Hoffmann-La Roche

Completed

A Double-Blind Single-Ascending Dose (SAD) and Multiple-Ascending Dose (MAD) Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7049389 in Healthy Chinese Participants

Hepatitis B Virus

China
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
Midas Pharma GmbH

Completed

Drug-drug-interaction Study of Ramipril, Amlodipine and Atorvastatin

Healthy Volunteers

Jordan
Services Institute of Medical Sciences, Pakistan

Unknown

Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial.

for Post-operative Pain Relief in Spine Surgeries

Pakistan
Eisai Inc.

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

Elderly | Chronic Insomnia | Adults

United States
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Malaria Research and Training Center, Bamako...

Completed

Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission (NECTAR1)

Malaria,Falciparum

Netherlands, Mali
Cedars-Sinai Medical Center

Completed

Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy

Becker Muscular Dystrophy

United States
GlaxoSmithKline

Completed

A Study to Evaluate Immune Response and Safety of Two Doses of GSK Biologicals' HRV Liquid Vaccine in Healthy Infants.

Infections, Rotavirus | Rotavirus Vaccines

Philippines
University of Wisconsin, Madison
Sanofi; Genzyme, a Sanofi Company

Terminated

Study of Docetaxel With Doxercalciferol or Placebo for Advanced Prostate Cancer

Prostate Cancer

United States
H. Lundbeck A/S

Terminated

Study to Evaluate the Safety and Tolerability of a New Drug Named Lu AF20513 in Patients With Mild Alzheimer's Disease

Alzheimer Disease

Austria, Finland, Sweden
Duke University

Terminated

Patient- and Task-specific Radiation Dose Optimization for Pediatric Abdominopelvic CT Applications

Split Dose CT

United States
University of Wisconsin, Madison
Tyrogenex

Completed

VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Docetaxel in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Health Decisions
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Unknown

Study Comparing Emergency Contraception Effectiveness in Women Who Weight ≥ 80 kg

Contraception

United States
Eisai Inc.

Completed

A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese Adults

Chronic Weight Management

United States
Sun Yat-sen University

Terminated

Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy

Polypoidal Choroidal Vasculopathy

China
Eli Lilly and Company

Completed

A Study to Compare the Effect of a Double Dose of Two Long-acting Insulin Therapies in Participants With Type 2 Diabetes (IMAGINE 8)

Type 2 Diabetes Mellitus

Germany, United States
Wex Pharmaceuticals Inc.
Celerion

Completed

A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate the Cardiovascular Effect of Tetrodotoxin in Healthy Adult Subjects

TQT Study

United States
United States Naval Medical Center, San Diego

Withdrawn

A Study to Decrease Suicidal Thinking Using Ketamine

Depression | Suicide

United States
Clovis Oncology, Inc.

Terminated

TIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet Chemotherapy

Non-small Cell Lung Cancer

Korea, Republic of, United States, France, Germany, Netherlands, Australia, Spain, Taiwan, United Kingdom, Italy
GlaxoSmithKline

Terminated

Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging

Idiopathic Pulmonary Fibrosis

United Kingdom
GlaxoSmithKline

Completed

Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)

Asthma

United States, Canada
University of Mississippi, Oxford

Completed

Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen

Malaria | Glucose 6 Phosphate Dehydrogenase Deficiency

United States
Michael Campos, MD
CSL Behring

Completed

Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.

Alpha 1 Antitrypsin Deficiency

United States
University of Dundee

Completed

Fluticasone/Salmeterol (FP/SM) Versus Double the Dose Fluticasone (FP) in Patients With Mild to Moderate Asthma (CLE001)

Asthma

United Kingdom
University of British Columbia

Completed

Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration (CIRCA-DOSE)

Paroxysmal Atrial Fibrillation

Canada
Ipsen

Completed

Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acromegaly

Acromegaly

France, Germany, Spain, Belgium, Russian Federation, United Kingdom, Italy, Lithuania, Czechia, Romania, Poland, Netherlands
University of Calgary
Pure North S'Energy Foundation

Completed

Dose-dependent Effects of Vitamin D on Bone Health

Age-Related Osteoporosis

Canada
ImmuPharma

Completed

A 52-Week, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus (LUPUZOR)

Lupus Erythematosus, Systemic

France, Puerto Rico, Poland, Mauritius, United States, Czechia, Germany, Hungary
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effectiveness and Safety of Different Doses of ASP1707 Compared to Placebo for Endometriosis Associated Pelvic Pain

Endometriosis

Belgium, Bulgaria, Germany, Hungary, Japan, Poland, Romania, Ukraine, United Kingdom
Dynavax Technologies Corporation

Terminated

A Safety and Efficacy Study of a Single or Double Dose of HEPLISAV™ Hepatitis B Vaccine in Adults With End-Stage Renal Disease

Hepatitis B

Canada
One World Cannabis Ltd.

Completed

A Phase I, Double Blind, Randomized, Placebo Controlled, Maximal Dose Study to Determine the Safety, Tolerability of Topical Cream Containing MGC (Medical Grade Cannabis) in Healthy Volunteers

Safety Study for Future Treatment of Psoriasis

Israel
Berg, LLC

Completed

Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma

Superficial Basal Cell Carcinoma

United States
Pluristem Ltd.

Completed

Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC)

Intermittent Claudication | Peripheral Artery Disease

United States, Germany, Korea, Republic of, Israel
Almirall, S.A.
Allergan

Completed

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Acne Vulgaris

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase 1 Trial of Inactivated West Nile Virus Vaccine

West Nile Viral Infection

United States
Cairo University

Completed

Different Doses of Vitamin D and T Regulatory Cells in Preterm Infants

Prematurity | Immune Defect
Torax Medical Incorporated

Completed

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease (CALIBER)

GERD Gastroesophageal Reflux Disease

United States

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