Search clinical trials for: Randomized open-label controlled clinical trial

Total 88308 results

Shanghai Eye Disease Prevention and Treatment Center
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Completed

The Effectiveness and Safety of Low-intensity Single-wavelength Red Light in Controlling High Myopia in Children and Adolescents：A Randomized, Controlled, Multicenter Clinical Trial

Age 3 to 16 Years (Inclusive), Male or Female | Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye | The Guardian Voluntarily Signed the Subject's Informed Consent Form

China
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Institute for Clinical Evaluative... and other collaborators

Completed

Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD)

Kidney Diseases | End Stage Renal Disease | Kidney Failure

Canada
University of California, San Francisco
National Institutes of Health (NIH)

Terminated

A Randomized, Placebo-controlled, Double-blind Clinical Trial of Curcuminoids in Oral Lichen Planus

Oral Lichen Planus

United States
Medesis Pharma SA

Terminated

NanoMn®_COVID-19 A Prospective, Multicenter, Randomized, Placebo-controlled, Parallel-group, Double-blind Trial to Evaluate the Clinical Efficacy of NanoManganese® on Top of Standard of Care, in Adult Patients With Moderate to Severe Coronavirus Disease 2019 (COVID-19)

COVID-19 Pandemic

Brazil
Fujian Medical University

Completed

The Effectiveness of At-home , In-office and Combined Dental Bleaching System ：A Randomized Controlled Clinical Trial

Tooth Bleaching

China
Bryan Schneider, MD
Hoosier Cancer Research Network; Walther Cancer Institute; Vera Bradley Foundation... and other collaborators

Completed

Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer

Breast Cancer | Malignant Neoplasm of Breast

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil (Remember)

Cognitive Dysfunction | Memory Impairment

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Suspended

Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

Cannabis

United States
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
AbbVie

Completed

A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC)

United States, Argentina, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico, Nether... and more
Biotech Pharmaceutical Co., Ltd.

Completed

A Real-world Study of the Efficacy and Safety of Nimotuzumab in Combination With Chemoradiotherapy for LASCCHN (Redbull-1)

Locally Advanced Head and Neck Squamous Cell Carcinoma

China
Second Affiliated Hospital, School of Medicine,...

Completed

A Single-center Randomized Controlled Study on the Effect of Pharmacogenomics Trial on Clinical Efficacy in Patients With Depression

Depressive Disorder | Pharmacogenomic Drug Interaction

China
Security Forces Hospital

Completed

Evaluation of Ultrasound-guided Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Sleeve Gastrectomy: A Prospective, Randomized, Controlled Clinical Trial (ESP)

Pain, Postoperative

Saudi Arabia
Beijing Tiantan Hospital
Ministry of Science and Technology of the People's Republic of China

Active, not recruiting

Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)

Transient Ischemic Attack | Acute Stroke

China
National Cardiovascular Center Harapan Kita Hospital...
Danone Institute International

Completed

The Effect of High-Calorie Formula on Nutritional and Clinical Outcomes Among Infants After Congenital Heart Surgery

Malnutrition, Child | Congenital Heart Disease in Children

Indonesia
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Effect of Olive Oil Massage on Growth in Preterm Low Birth Weight Neonate: A Randomized Controlled Clinical Trial

Weight Gain

Bangladesh
Ain Shams University

Completed

The Impact of Root End Filling Material Type and the Application of Bone Graft on Healing of Periapical Tissues After Endodontic Microsurgery (A Clinical Randomized Controlled Trial)

Periapical Diseases | Periapical Cyst

Egypt
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer

High Grade Upper Tract Urothelial Carcinoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Invasive Breast Carcinoma | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Stage...

United States, South Africa
Ain Shams University

Completed

Role of Ivermectin and Colchicine in Treatment of COVID-19: Randomized Controlled Clinical Trial

COVID-19

Egypt
Satsuma Pharmaceuticals, Inc.

Completed

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine (EMERGE)

Migraine | Migraine Without Aura | Migraine With Aura

United States
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Ottawa Hospital Research Institute and other collaborators

Completed

Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP)

Kidney Diseases | Hemodialysis | End-Stage Kidney Disease

Canada
National Institute of Allergy and Infectious Diseases...
PPD; University of Washington; Vanderbilt University Medical Center; Implicit Bioscience

Terminated

COVID-19 and Anti-CD14 Treatment Trial (CaTT)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Coronavirus Disease 2019 (COVID-19)

United States
Insel Gruppe AG, University Hospital Bern

Active, not recruiting

Decompressive Hemicraniectomy in Intracerebral Hemorrhage (SWITCH)

Cerebral Hemorrhage

Belgium, France, Germany, Finland, Austria, Netherlands, Spain, Switzerland
Philogen S.p.A.

Terminated

A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX

Rheumatoid Arthritis

Switzerland, Germany, Italy
Aldeyra Therapeutics, Inc.

Completed

A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Rigel Pharmaceuticals

Completed

A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA

Warm Antibody Autoimmune Hemolytic Anemia

United States, Spain, Canada, Australia, Norway, France, Belarus, Germany, Netherlands, Belgium, United Kingdom, Austria, Czechia, Georgia, Italy, Russian Federation, Serbia, Ukraine, Romania, Denmark, Hungary, Bulgaria
Naga P. Chalasani
DSM Nutritional Products, Inc.

Completed

Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD) (PUVENAFLD)

Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis | Non-Alcoholic Fatty Liver

United States
University of Zurich

Active, not recruiting

Two Implants Versus One Implant With a Cantilever - a Randomized Controlled Clinical Trial

Dental Implants

Switzerland
American University of Beirut Medical Center

Completed

Nonopioid Analgesics and Cholecystectomy

Pain, Postoperative | Opioid Use | Cholecystectomy

Lebanon
Anhui Medical University

Completed

Exercise Interventions on Problematic Mobile Phone Use: a Multi-arm Randomized Controlled Trial

Randomized Clinical Trial | Intestinal Flora | Exercise Intervention | Tai Chi Chuan

China
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

PanACEA Sutezolid Dose-finding and Combination Evaluation (SUDOCU)

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
American Regent, Inc.
Duke Clinical Research Institute

Completed

Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency (HEART-FID)

Heart Failure | Iron-deficiency

United States, Canada, Australia, Bulgaria, Georgia, New Zealand, Latvia, Hungary, Poland, Czechia, Lithuania, Russian Federation, Ukraine
University of British Columbia
Ministry of Health, British Columbia

Completed

Evaluation of Therapeutic Initiative's Cystitis Portrait and Therapeutics Letter

Quality Improvement | Clinical Audit

Canada
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Al... and other collaborators

Completed

Mindfulness Based Cognitive Therapy for Bipolar Disorder (MBCT-BD)

Bipolar Disorder

Netherlands
Fujian Medical University

Completed

Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer

Stomach Neoplasms
University of Bari Aldo Moro
IGEA

Completed

CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial

Vertebral Fracture | Osteoporotic Fractures
University of Sao Paulo
Instituto Dante Pazzanese de Cardiologia

Completed

Efficacy of the PEAC-IC: a Randomized Controlled Clinical Trial (PEAC-IC)

Heart Failure

Brazil
Women's College Hospital
Sunnybrook Health Sciences Centre; Canadian Institutes of Health Research (CIHR) and other collaborators

Completed

Avoiding Diabetes After Pregnancy Trial in Moms (ADAPT-M)

Diabetes

Canada
Hospital Universitari de Bellvitge

Completed

Feasibility and Effect of a Multidisciplinary Telematics Approach for Chronic Non-specific Low Back Pain: a Randomized, Open-label, Controlled, Pilot Clinical Trial. Study Protocol

Low Back Pain

Spain
Federal University of São Paulo
University of Sao Paulo

No longer available

CLINICAL TRIAL PHASE II, MULTICENTRIC, NATIONAL, DOUBLE-BLIND, PARALLEL, RANDOMIZED, AND PLACEBO-CONTROLLED FOR EVALUATION OF THE IMPROVEMENT OF SLEEP QUALITY IN PARTICIPANTS OF RESEARCH WITH INSOMNIA DISORDER

Sleep Initiation and Maintenance Disorders
Elizabeth Glaser Pediatric AIDS Foundation
University of Sheffield; Epicentre; Institut de Recherche pour le Developpement

Completed

Community-based Tuberculosis Tracing and Preventive Therapy (CONTACT)

Tuberculosis

Uganda, Cameroon
Alejandro Reyes Sánchez

Completed

Clinical Trial Analyzing the Efficacy of Oral Administration of Tranexamic Acid in Spine Surgery.

Randomized Controlled Trial | Prospective Study | Tranexamic Acid (TXA) | Evidence-based Medicine

Mexico
Aldeyra Therapeutics, Inc.

Completed

A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)

Atopic Asthma

Canada
Yu Qin

Active, not recruiting

An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older

Prevention of COVID-19 Caused by SARS-CoV-2

China
University of Sao Paulo

Completed

Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin

Dental Caries

Brazil
Indiana University
National Institute on Aging (NIA); Regenstrief Institute, Inc.; Hebrew SeniorLife

Completed

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support (APPROACHES)

Dementia | Alzheimer Disease

United States
Universidad Complutense de Madrid

Active, not recruiting

Leukocyte and Platelet-rich Fibrin (L-PRF) Effects on Alveolar Ridge Preservation. A Randomized Controlled Clinical Trial.

Dental Implants | Alveolar Ridge Preservation

Spain
NovaCell Technology Inc.

Completed

A Single-center, Randomized, Double-blinded, Placebo-controlled, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of NCP112

Atopic Dermatitis

Korea, Republic of

Search clinical trials for: Randomized open-label controlled clinical trial

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