Search clinical trials for: TDF

Total 391 results

Centers for Disease Control and Prevention
Gilead Sciences; Botswana Ministry of Health

Completed

Botswana TDF/FTC Oral HIV Prophylaxis Trial (TDF2)

HIV Infections

United States, Botswana
ViiV Healthcare
GlaxoSmithKline

Completed

Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus Rilpivirine

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Canada
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, United Kingdom, Switzerland, Germany, Canada, France, Belgium, Puerto Rico
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
IlDong Pharmaceutical Co Ltd

Unknown

Switching From Tenofovir Disoproxil Fumarate to Besifovir Dipivoxil Maleate

Hepatitis B | Besifovir Dipivoxil Maleate | Tenofovir Disoproxil Fumarate

Korea, Republic of
New Discovery LLC
Gilead Sciences

Completed

Tenofovir in Late Pregnancy to Prevent Vertical Transmission of Hepatitis B Virus

Viremia | Hepatitis B Infection | Chronic Infection

China
Kirby Institute

Completed

PrEP Demonstration Project (PRELUDE Study) (PRELUDE)

HIV

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma (REACT-KS)

Kaposi's Sarcoma | HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Uganda
Qing XIe
Shanghai MedSci Healthcare Co. Ltd

Unknown

Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis

Hepatocellular Carcinoma | Hepatitis B, Chronic | Compensated Cirrhosis

China
Qilu Pharmaceutical Co., Ltd.

Unknown

An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Tenofovir in Naive Patients With Chronic Hepatitis b

Chronic Hepatitis b

China
Qilu Pharmaceutical Co., Ltd.

Unknown

An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Entecavir or Tenofovir in Patients With Chronic Hepatitis b Who Have Received Nucleoside (Acid) Therapy

Chronic Hepatitis b

China
GlaxoSmithKline

Completed

Tenofovir Disoproxil Fumarate (TDF) 300mg 3 Years RD Therapy Chinese Chronic Hepatitis B (CHN) CHB Multiple Nucleos(t)Ide Analogues (NAs) Failure Points Pts PH4 PMS Study

Hepatitis B, Chronic

China
Beijing Ditan Hospital

Unknown

Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B

Chronic Hepatitis B Infection | High Viral Load

China
ANRS, Emerging Infectious Diseases

Unknown

Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmission (TA-PROHM)

Pregnancy | Hepatitis B Chronic Infection

Cambodia
Sunshine Lake Pharma Co., Ltd.

Completed

A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects

Chronic Hepatitis B

China
HeNan Sincere Biotech Co., Ltd
Beijing YouAn Hospital; Beijing Ditan Hospital; Peking Union Medical College... and other collaborators

Completed

A Drug Safety and Dose-exploratory Clinical Study of Azvudine Tablets in Patients Who Have Not Received Anti-HIV Treatment (FNC)

AIDS

China
Thomas Jefferson University

Completed

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

Hyperglycemia | Cardiovascular Diseases | Metabolic Syndrome | Weight Gain | HIV-1-infection | Renal Function Abnormal

United States
Gilead Sciences

Completed

Safety and Efficacy of E/C/F/TDF Versus RTV-Boosted ATV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment-Naive Women (WAVES)

HIV Infections | Acquired Immunodeficiency Syndrome

United States, Thailand, France, Uganda, United Kingdom, Belgium, Portugal, Mexico, Dominican Republic, Italy, Puerto Rico, Russian Federation
South East Asia Research Collaboration with Hawaii
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Using Telmisartan With ART During Acute HIV Infection to Reduce the CNS Reservoirs of HIV and Lymph Node Fibrosis

Acute HIV Infection | HIV CNS Involvement

Thailand
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; Kirby Institute

Completed

Tenofovir Renal Toxicity and Glomerular Filtration Rate (GFR) Validation

HIV Infection | Renal Function

Thailand
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected

HIV-1 Infection | Pf Subclinical Parasitemia

Kenya, Malawi, Uganda
Felipe Garcia

Completed

Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively Treated

HIV-1 Infection

Spain
ANRS, Emerging Infectious Diseases

Completed

First-Line Treatment for HIV-2 (FIT-2)

HIV-2 Infection

Côte D'Ivoire, Burkina Faso, Senegal, Togo
Auritec Pharmaceuticals
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Safety and Pharmacokinetic Study of HIV Prophylaxis Using Antiretroviral Intravaginal Rings in Healthy Women

Human Immunodeficiency Virus (HIV) Prophylaxis

United States
Gilead Sciences

Completed

Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Participants With Chronic Hepatitis B (CHB) and Who Are Currently Not on Treatment

Chronic Hepatitis B

Korea, Republic of, Canada, United States, New Zealand, Italy, Romania
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Patient-donor Vaccination in the Context of Allogeneic Bone Marrow Transplant With Post-transplant Cyclophosphamide

Transplant-Related Cancer

United States
Mahidol University

Completed

Switching TDF/FTC/EFV to TDF/FTC/RPV VS Continuing TDF/FTC/EFV in HIV Patients With Complete Virological Suppression (STEREOS)

Dyslipidemias | HIV-1-infection | Sustained Virologic Response | Anti-Retroviral Agents | Efavirenz | Rilpivirine
University of Washington
Bill and Melinda Gates Foundation

Completed

Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant Couples (Partners PrEP)

HIV Infections | HIV-1 Infections

Kenya, Uganda
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

Renal, Endocrine, and Bone Changes in Response to FTC/TDF in Uninfected Young Men Who Have Sex With Men (YMSM).

HIV Infection

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Efficacy and Safety of Domestic Tenofovir Tablets in Chinese Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
Myeong Jun Song
Gilead Sciences; Soonchunhyang University Hospital; Chungnam National University... and other collaborators

Completed

Treatment Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) in naïve Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
The Catholic University of Korea

Unknown

Treatment Efficacy and Safety of TDF-TAF Switch Study in South Korea

Chronic Hepatitis b

Korea, Republic of
Yale University

Withdrawn

Betadine Pleurodesis Via Tunneled Pleural Catheters

Pleural Effusion | Malignant Pleural Effusion | Pleurodesis | Pleural Effusions, Chronic | Pleural Effusion Due to Congestive Heart Failure | Pleural Effusion in Conditions Classified Elsewhere
Qilu Pharmaceutical Co., Ltd.

Unknown

A Study to Investigate the Safety, Efficacy and PK of Multiple Doses of QL-007 in Chronic Hepatitis B Patients in CHINA (QL-007)

Chronic Hepatitis b

China
Gilead Sciences

Completed

Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

HIV Infections | Acquired Immunodeficiency Syndrome

United States, Puerto Rico
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults

HIV Infections | HIV

United States, Spain, Switzerland, Canada, Thailand, Puerto Rico, Australia, Austria, Belgium, Italy, Japan, United Kingdom
Gilead Sciences

Completed

A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B

Chronic Hepatitis B

Canada, United States, United Kingdom, Australia, New Zealand
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission (OCTANE)

HIV Infections

South Africa, Botswana, Kenya, Malawi, Uganda, Zambia, Zimbabwe
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults

HIV Infections

United States, Puerto Rico
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART

HIV-1 Infection

United States, Puerto Rico
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected Adults

HIV Infections

Peru, Brazil, South Africa, Uganda, Botswana, Haiti, Zambia, Zimbabwe
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings (PEARLS)

HIV Infections

United States, Brazil, Peru, India, Malawi, Haiti, South Africa, Thailand, Zimbabwe
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Trial Comparing GSK1349572 50mg Once Daily to Raltegravir 400mg Twice Daily (SPRING-2)

Infection, Human Immunodeficiency Virus I

Germany, Spain, France, Australia, United States, Canada, United Kingdom, Italy, Russian Federation
Fuzhou General Hospital

Completed

TDF and LdT in Immune-tolerant CHB Patients Awaiting Assisted Reproduction

Hepatitis B, Chronic

China
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults

Infection, Human Immunodeficiency Virus

United States, France, Germany, Canada, Spain, United Kingdom, Mexico, Italy, Argentina, Chile, South Africa, Poland
Emory University

Completed

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

HIV

United States, South Africa
Albert Einstein College of Medicine
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-001)

HIV

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Optimizing Pediatric HIV-1 Treatment in Infants With Prophylactic Exposure to Nevirapine, Nairobi, Kenya

HIV Infections

Kenya
Marla Keller
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002) (TDF IVR-002)

Healthy | HIV

United States, Kenya

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