Search clinical trials for: cancer therapies

Total 88160 results

Memorial Sloan Kettering Cancer Center
University of Southern California; Weill Medical College of Cornell University and other collaborators

Active, not recruiting

Development of Psychotherapeutic Interventions for Parents Who Lost a Child

Parents Who Have Lost a Child

United States
Affimed GmbH

Completed

Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides (REDIRECT)

Peripheral T Cell Lymphoma | Transformed Mycosis Fungoides

Spain, United States, Korea, Republic of, Italy, France, Australia, Germany, Poland, Turkey, Russian Federation
MEI Pharma, Inc.

Terminated

Zandelisib (ME-401) in Subjects With Follicular Lymphoma or Marginal Zone Lymphoma After Failure of Two or More Prior Therapies (TIDAL)

Marginal Zone Lymphoma | Non Hodgkin Lymphoma | Follicular Lymphoma (FL)

United States, Spain, Korea, Republic of, Belgium, Taiwan, Germany, France, Italy, Australia, Poland, New Zealand, United Kingdom, Austria, Switzerland
Okan University
Istanbul University

Completed

Effects of Therapeutic Play on Anxiety and Fear

Pediatric Cancer

Turkey
Merck Sharp & Dohme LLC

Active, not recruiting

Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B)

Carcinoma, Renal Cell

United States, Australia, Canada, Chile, France, Hungary, Israel, Korea, Republic of, Netherlands, New Zealand, Poland, Spain, United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Active, not recruiting

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer (REACTION)

Gastroesophageal Cancer | Immune Checkpoint Inhibition

United States
New Mexico Cancer Care Alliance

Terminated

Acute Lymphoblastic Leukemia Therapies Informed by Genomic Analyses

Leukemia, Acute Lymphoblastic

United States
University Health Network, Toronto

Active, not recruiting

A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes

Salivary Gland Cancer | Metastatic | Recurrent | Advanced

Canada
Hunan Province Tumor Hospital

Completed

Association Between the Results of Specific Genetic Tests and the Efficacy of Targeted Therapies in Patients

Non-small Cell Lung Cancer

China
Ferring Pharmaceuticals
FKD Therapies Oy; Society of Urologic Oncology Clinical Trials Consortium

Completed

ADSTILADRIN (=INSTILADRIN) in Patients With High Grade, Bacillus Calmette-Guerin (BCG) Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC)

Superficial Bladder Cancer

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; Pfizer; Janssen Scientific Affairs, LLC

Completed

Maximal Androgen Depletion Followed by Randomization of Maximal Androgen Ablation With Molecular Targeted Therapies

Prostate Cancer

United States
Gilead Sciences

Active, not recruiting

Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell Malignancies

B-cell Malignancies

United States, United Kingdom, France
International Myeloma Foundation
Janssen Scientific Affairs, LLC; Celgene; Amgen; Trevie, Inc.

Active, not recruiting

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT)

Smoldering Multiple Myeloma

United States
Cliniques universitaires Saint-Luc- Université...

Active, not recruiting

Prospective Collection of Tumor Biopsy and Plasma Samples From Cancer Patients Treated With Molecular Targeted Therapies or Immunotherapy (Plasma-Target)

Cancer

Belgium
UNICANCER
Pfizer

Active, not recruiting

Locoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer Patients (PALATINE)

Surgery | Breast Cancer Stage IV | Radiotherapy

France
SCRI Development Innovations, LLC
Bayer; Boehringer Ingelheim; Exelixis; Foundation Medicine

Completed

Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations

Non-small Cell Lung Carcinoma | Urothelial Carcinoma | Gastrointestinal Carcinoma, Non-colon | Upper Aerodigestive Tract Carcinoma

United States
SCRI Development Innovations, LLC
Incyte Corporation

Terminated

A Study of Itacitinib for the Treatment of Chronic Graft Versus Host Disease (cGVHD)

Chronic Graft-versus-host-disease

United States
University of Malaga

Completed

Clinical and Functional Variables in Oncology (Oncolab)

Cancer | Survivorship | Cancer, Metastatic

Spain
Jennifer Choe
Arcus Biosciences, Inc.

Withdrawn

A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers (PANTHEoN)

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Oropharynx Cancer | Oral Cavity Cancer | Oropharynx Squamous Cell Carcinoma | Pharynx Cancer | Larynx Cancer | Hypopharynx Cancer | Oral Cavity Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

United States
Arog Pharmaceuticals, Inc.

Completed

A Phase II Study of Crenolanib in Relapsed/Refractory Acute Myeloid Leukemia Patients With FLT3 Activating Mutations

Acute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior Therapies

United States
University of Coimbra
Portuguese Oncology Institute, Coimbra

Completed

Well-being Biomarkers (BIOSMILE) & Psychology Analyses in Women With Cancer After Hospital Clowns and Hosting Effects

Cancer | Biomarkers | Complementary Therapies | Ambulatory Care | Well-Being, Psychological

Portugal
MedImmune LLC

Terminated

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Metastatic Microsatellite-stable Colorectal Cancer

United States, Spain, France, Australia, Canada
University of Barcelona

Enrolling by invitation

Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC

Quality of Life | Periodontal Diseases | Dysbiosis | Dental Plaque | Xerostomia | Oral Mucositis

Spain
Amgen

Terminated

Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

United States, Sweden, Spain, United Kingdom, Australia, Denmark
Boehringer Ingelheim

Completed

Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma

Non-squamous, Non-Small Cell Lung Cancer

Japan
Sun Pharma Advanced Research Company Limited

Active, not recruiting

Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies

Healthy (For Part A) | Chronic Myeloid Leukemia (for Part B and C)

United States, Spain, Hungary, Italy, India, Belgium, France, Romania, Singapore, United Kingdom, Korea, Republic of, Turkey
National Cancer Institute (NCI)

Completed

Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)

Neurofibromatosis 1 | Peripheral Nerve Neoplasms, Malignant

United States
Cancer Trials Ireland

Completed

Exosomal and Free Extracellular RNAs and Proteins as Predictive Biomarkers for HER2 Therapies in Breast Cancer

Breast Cancer | HER2 Positive Breast Cancer | HER2 Negative Breast Cancer

Ireland
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC; Seagen Inc.

Active, not recruiting

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer (EV-103)

Urologic Neoplasms | Urinary Bladder Neoplasms | Carcinoma, Transitional Cell | Ureteral Neoplasms | Urothelial Cancer | Urethral Neoplasms | Renal Pelvis Neoplasms

United States, Italy, Spain, Canada, France, Puerto Rico
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Phase 1a Study Evaluating the Safety, Tolerability, and Efficacy of IBI322 in Subjects With Advanced Cancers

Advanced Malignant Tumors Lymphomas

United States
NovoCure GmbH

Active, not recruiting

Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

NSCLC | Nonsmall Cell Lung Cancer

United States, Poland, Hong Kong, China, Spain, Serbia, Croatia, France, Canada, Netherlands, Austria, Belgium, Bulgaria, Czechia, Germany, Hungary, Italy, Switzerland
Heat Biologics

Completed

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

United States
First Affiliated Hospital of Wenzhou Medical University
Qilu Hospital of Shandong University; Eastern Hepatobiliary Surgery Hospital; The First Affiliated Hospital of Zhejiang Chinese Medical University

Enrolling by invitation

Effect of Sarcopenia on Hepatocellular Carcinoma(HCC) After Systemic Therapies

Hepatocellular Carcinoma | Sarcopenia

China
Innovent Biologics (Suzhou) Co. Ltd.

Withdrawn

IBI397 or Combination Therapies in Patients With Advanced Malignancies

Advanced Malignancies

China
University of Florida

Completed

Gemcitabine With Abraxane and Other Investigational Therapies in Neoadjuvant Treatment of Pancreatic Adenocarcinoma (GAIN-1)

Pancreatic Cancer

United States
David Bushnell
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Active, not recruiting

Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors

Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting | Neuroendocrine Tumor, Malignant

United States
Baylor College of Medicine
Harris County Hospital District; The Methodist Hospital Research Institute; Center... and other collaborators

Active, not recruiting

TAA Specific Cytotoxic T Lymphocytes in Patients With Pancreatic Cancer (TACTOPS)

Pancreatic Cancer

United States
Institut Bergonié
Institut du Cancer de Montpellier - Val d'Aurelle; UNICANCER

Active, not recruiting

Survival Endpoints for Treatment Evaluation in Subjects Treated for Metastatic Breast Cancer: Contribution of Real-life Databases

Cancer

France
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies

Solid Tumor | Hematologic Malignancy | Solid Tumor, Adult | Solid Carcinoma

United States
Erasca, Inc.

Completed

A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC (HERKULES-2)

Advanced Non-squamous Non-small-cell Lung Cancer

United States
Charite University, Berlin, Germany

Completed

Evaluation of a Oncology Day Care Unit Programme With Two Different Focuses (TK-Onko)

Cancer

Germany
Albert Einstein College of Medicine
American Cancer Society, Inc.

Completed

Mind-Body Program for Cancer Patients

Neoplasms

United States
The Mediterranean Institute for Transplantation...
Azienda Ospedaliero, Universitaria Pisana; Università degli Studi di Ferrara; Azienda Ospedaliera di Perugia and other collaborators

Enrolling by invitation

Italian Lung Cancer Observational Study (LUCENT)

Lung Cancer

Italy
Memorial Sloan Kettering Cancer Center
Medivation, Inc.

Completed

Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies

Primary Peritoneal Carcinoma | Fallopian Tube | Advanced Epithelial Ovarian | Recurrent Epithelial Ovarian

United States
Tulane University
Blue Earth Diagnostics

Completed

18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies

Metastatic Castration-resistant Prostate Cancer

United States
M.D. Anderson Cancer Center

Completed

High-Flow Oxygen for Dyspnea in Hospitalized Cancer Patients

Cancer

United States
Groupe Hospitalier Pitie-Salpetriere

Completed

Chimeric Antigen Receptor T-cell and Cellular Therapies for the Treatment of cAncer or BLood Diseases: Evaluation of Reporting of Adverse Events (CARTABLE)

Cancer | Adverse Drug Reactions

France
Revolution Medicines, Inc.
Sanofi; Amgen

Active, not recruiting

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Non-Small Cell Lung Cancer

United States, Korea, Republic of, Canada, Taiwan, Spain, United Kingdom, Italy, Australia, France, Germany
National Cancer Institute (NCI)

Completed

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Hepatocellular Carcinoma | Cholangiocarcinoma | Bile Duct Cancer | Biliary Tract Neoplasms | Liver Cancer

United States
Linda E. Carlson
Alberta Health services; University of Calgary; Princess Margaret Hospital, Canada and other collaborators

Active, not recruiting

The MATCH Study: Mindfulness And Tai Chi for Cancer Health (MATCH)

Cancer

Canada

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