Search clinical trials for: cytotoxic activity against T-LGL cells

Total 22695 results

National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3

HIV Infections

United States
ADC Therapeutics S.A.

Terminated

Safety and Antitumor Activity Study of Loncastuximab Tesirine and Durvalumab in Diffuse Large B-Cell, Mantle Cell, or Follicular Lymphoma

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Mantle Cell Lymphoma

Spain, United States
AstraZeneca

Completed

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Chronic Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | High Risk Myelodysplastic Syndrome | Small Lymphocytic Lymphoma | B-cell Non-Hodgkin Lymphoma | Richter's Syndrome | T-cell Non-Hodgkin Lymphoma | Relapsed or Refractory...

United Kingdom, Germany, Netherlands
National Research Center for Preventive Medicine

Completed

Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive Postmenopausal Women (COMPASS)

Osteopenia | Arterial Hypertension

Russian Federation
Tanta University

Completed

Antibacterial and Anti-biofilm Activity of Frankincense Extract Against Porphyromonas Gingivalis

Periodontal Diseases

Egypt
Implicit Bioscience

No longer available

Compassionate Use Open-Label Anti-CD14 Treatment in Patients With SARS-CoV-2 (COVID-19)

COVID | SARS-CoV2 | ARDS, Human | Ards

Italy
Jonsson Comprehensive Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Vaccinex Inc.

Terminated

Anti-SEMA4D Monoclonal Antibody VX15/2503 With Nivolumab or Ipilimumab in Treating Patients With Stage III or IV Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
University of Southern Denmark
National Cancer Institute (NCI); Odense University Hospital; University of California... and other collaborators

Unknown

Validation of Objectively and Subjectively Measured Physical Activity Against Energy Expenditure in Older Adults

no Condition, Community-dwelling 80+ Older Adults

Denmark
Assiut University

Unknown

The Relationship Between Workplace Environment and Metabolic Syndrome in Different Industries

Metabolic Syndrome, Protection Against
Azienda Ospedaliera Città della Salute e della...

Completed

Physical Activity in Children During Hematopoietic Stem Cells Transplantation (HSCT)

Adolescent | Child | Hematopoietic Stem Cell Transplantation

Italy
Instituto de Investigación Sanitaria de la Fundación...
Hospital General Universitario Gregorio Marañon; Clinica Universidad de Navarra... and other collaborators

Suspended

BAttLe Against COVID-19 Using MesenchYmal Stromal Cells

COVID | Respiratory Distress Syndrome

Spain
National Cancer Institute (NCI)

Withdrawn

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

Metastatic HPV-16 Positive Squamous Cell Anal Cancer

United States
The Interregional Association for Clinical Microbiology...

Completed

In Vitro Activity of Ceftolozane-tazobactam Against Contemporary Nosocomial Gram "-" Pathogens Isolated in Russia

Nosocomial Infection

Russian Federation
Zagazig University
University of California, Irvine; Charles Drew University of Medicine and Science and other collaborators

Completed

Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses

Influenza-like Illness

Egypt
Cairo University

Unknown

Oxidative Stress in Response to Electroacupuncture Against Physical Activity in Diabetic Patients

Diabetes Mellitus, Type 2

Egypt
Assistance Publique - Hôpitaux de Paris
Fondation ARSEP/AFM

Completed

Biological Activity and Safety of Low Dose IL2 in Relapsing Remitting Multiple Sclerosis (MS-IL2)

Relapsing Remitting Multiple Sclerosis

France
Fuda Cancer Hospital, Guangzhou
Jinan University Guangzhou

Completed

Safety and Efficiency of IRE Plus γδ T Cell Against Locally Advanced Pancreatic Cancer

Pancreatic Cancer

China
Sunesis Pharmaceuticals

Terminated

Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Lymphoplasmacytoid Lymphoma

United States
George Washington University

Withdrawn

Diet, Physical Activity and Body Composition Changes During R-CHOP (R-CHOP-OS)

Non-Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | DLBCL

United States
Huashan Hospital
Fudan University

Unknown

Study of DC Vaccination Against Glioblastoma

Glioma | Neoplasms | Glioblastoma Multiforme

China
National Institutes of Health Clinical Center (CC)

No longer available

Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Main Line Fertility Center

Completed

Mitochondrial Activity of Cumulus Cells From the Cumulus-oocyte Complex and Oocyte Competence

Infertility

United States
Children's National Research Institute
M.D. Anderson Cancer Center

Completed

Cytotoxic T Cells to Prevent Virus Infections

CMV | EBV | Adenovirus Infections

United States
Fuda Cancer Hospital, Guangzhou
Jinan University Guangzhou

Completed

Safety and Efficiency of γδ T Cell Against Lung Cancer

Lung Cancer

China
Fuda Cancer Hospital, Guangzhou
Jinan University Guangzhou

Completed

Safety and Efficiency of γδ T Cell Against Breast Cancer

Breast Cancer

China
Fuda Cancer Hospital, Guangzhou
Jinan University Guangzhou

Completed

Safety and Efficiency of γδ T Cell Against Liver Cancer

Liver Cancer

China
University of Zagreb

Unknown

Tooth Whitening Evaluation With Cytotoxic and Genotoxic Effect of Commercial Whitening Toothpastes on Oral Mucosal Cells

Teeth Whitening

Croatia
Fauqué
Institut Polyclinique de Cannes (IPOCA)

Completed

Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study (PPAR-NAPAS)

Obesity | Female | Obesity, Abdominal | Obesity, Visceral

France
Celyad Oncology SA

Unknown

Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases (SHRINK)

Colon Cancer Liver Metastasis

Belgium
Memorial Sloan Kettering Cancer Center

Withdrawn

Safety and Effectiveness of EBV-specific Cytotoxic T Cells for the Treatment for EBV Lymphomas or Other EBV-associated Malignancies

EBV Lymphomas | EBV-associated Malignancies
Mesoblast, Ltd.

Completed

Safety Study of Mesenchymal Precursor Cells in Type 2 Diabetes

Type 2 Diabetes

United States
Guangzhou First People's Hospital

Unknown

To Explore the Effect of GH on Outcomes of IVF and Telomerase Activity of Granulosa Cells in Women With POR

GH | Poor Ovarian Reserve Based on POSEIDON
Università degli Studi dell'Insubria

Unknown

Monocytes and NK Cells Activity in Covid-19 Patients

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | Immunomodulation

Italy
CytoVac A/S

Completed

Autologuos Lymphoid Effector Cells Specific Against Tumour (ALECSAT) as Add on to Standard of Care in Patients With Glioblastoma (ALECSAT)

Glioblastoma

Sweden
Shenzhen Geno-Immune Medical Institute

Unknown

Genetically Modified T Cells Against Ovarian Cancer

Ovarian Cancer

China
M.D. Anderson Cancer Center
Miltenyi Biotec B.V. & Co. KG

Completed

Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Cytomegalovirus (CMV) Reactivation

Lymphoma | Leukemia

United States
GlaxoSmithKline

Terminated

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas, Solid Tumors and Multiple Myeloma

Neoplasms | Cancer

United States, United Kingdom, France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

NK Cells in Cord Blood Transplantation

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia and other conditions

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases (MALTED)

Nasopharyngeal Carcinoma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Leiomyosarcoma | Lymphoproliferative Disorder | Severe Chronic Active EBV (SCAEBV)

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States, Italy
Sidney Kimmel Comprehensive Cancer Center at Johns...
Novartis Pharmaceuticals; The Skip Viragh Foundation

Terminated

Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic Adenocarcinoma

Pancreatic Ductal Adenocarcinoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

Recurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Mantle Cell Lymphoma | Waldenstrom Macroglobulinemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood... and other conditions

United States
International Centre for Diarrhoeal Disease Research...
Medical Research Council, South Africa; BSR; Change Associates Limited

Completed

HERrespect Evaluation (HERrespect)

IPV | Workplace Violence
Rigshospitalet, Denmark

Completed

PROstaTe Cancer - Exercise-STudy (PRO-TEST) (PRO-TEST)

Prostate Cancer

Denmark
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral Infections

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | MDS (Myelodysplastic Syndrome) | CML (Chronic Myelogenous Leukemia) | AML (Acute Myelogenous Leukemia)

United States
Rigshospitalet, Denmark

Completed

The Effect of Exercise on Tumor Hypoxia in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy. (SHOR-TEST)

Prostate Cancer

Denmark
The First Affiliated Hospital of Nanchang University

Unknown

Humanized CAR-T Cells of Anti-BCAM and Anti-CD19 Against Relapsed and Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

China
GlaxoSmithKline
Merck Sharp & Dohme LLC

Withdrawn

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

Neoplasms
Shenzhen Geno-Immune Medical Institute

Unknown

Engineered Immune Effectors Against Ovarian Cancer

Ovarian Cancer

China

Search clinical trials for: cytotoxic activity against T-LGL cells

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