Search clinical trials for: first-line drugs

Total 256744 results

University of Wisconsin, Madison
Fogarty International Center of the National Institute of Health

Not yet recruiting

Community Health Worker-led Hypertension Management

Hypertension
Sanofi

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

Alopecia Areata
Rigshospitalet, Denmark

Not yet recruiting

Cocaine, Lidocaine/Xylometazoline and Saline for Nasal Analgesia

Analgesia
Peking University Cancer Hospital & Institute

Not yet recruiting

Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer (PKUCH-R09)

Rectal Cancer

China
Columbia University
University of Southern California; Abdul Latif Jameel Poverty Action Lab; Bowdoin... and other collaborators

Not yet recruiting

E-mail Nudges for Prescribing Risky Drugs

Opioid Prescribing | Prescription Drug Misuse

United States
Mahidol University

Recruiting

The Effect of Smartphone Application on the Quality of Bowel Preparation for Colonoscopy

Colonoscopy | Bowel Preparation | Smartphone Application | Quality

Thailand
Peking University

Recruiting

Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan

Colorectal Cancer | Solid Tumor

China
Hunan Normal University

Not yet recruiting

Effects of Adaptive Physical Activity on Health-related Fitness of Students With Intellectual Disabilitiesdisability

Intellectual Disability
Istituto Clinico Humanitas

Not yet recruiting

Suturing Through-the-scope System Used for Prophylactic Closure of Colonic Post-ESD Defects (STITCH)

Precancerous Lesion of Colon
Necmettin Erbakan University

Not yet recruiting

Needle and Shotblocker on Pain and Satisfaction in Intramuscular Injection Pain

Intramuscular Injection
Nanfang Hospital, Southern Medical University
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Not yet recruiting

hAESCs Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation

Acute Graft Versus Host Disease
Institut d'Investigació Biomèdica de Girona Dr....
Germans Trias i Pujol Hospital; University Hospital of Girona Dr.Josep Trueta

Recruiting

Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis

Bronchiectasis Adult

Spain
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Lei Liu

Not yet recruiting

A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma
RAND
Innovations for Poverty Action; Clinton Health Access Initiative, Nigeria

Not yet recruiting

The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea

Diarrhea Toddler
Başakşehir Çam & Sakura City Hospital

Recruiting

Comparison of Pain Relief After Hip Fracture Surgery: Hip and Groin Nerve Block

Pain, Postoperative | Hip Fractures | Opioid Use

Turkey
Novartis Pharmaceuticals

Not yet recruiting

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis (KATHAROS)

Multiple Sclerosis
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
Mayo Clinic

Not yet recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

WHO Grade 3 Glioma | WHO Grade 2 Glioma | WHO Grade 4 Glioma

United States
Hasselt University
Ziekenhuis Oost-Limburg; Research Foundation Flanders

Recruiting

Differences in Extracellular Vesicles From Adipose Tissue of Individuals With Obesity. (EVO)

Obesity

Belgium
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

A Machine Learning Prediction Model for Delayed CIPONV

Postoperative Nausea and Vomiting

China
Regeneron Pharmaceuticals

Not yet recruiting

Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants

Healthy Volunteers
Balgrist University Hospital

Recruiting

Loss and Return of Sensation After Axillary Brachial Plexus Nerve Block - Distally or Proximally (LRNB)

Anesthesia

Switzerland
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

COVID-19

United States
Masonic Cancer Center, University of Minnesota

Not yet recruiting

Remote Trial - Tobacco Product Standard (VLNC)

Tobacco Use
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Not yet recruiting

M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis

Radiation Dermatitis

United States
Rethink Wellbeing
Maastricht University

Not yet recruiting

Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity. (CT_DoBetter)

Depression | Quality of Life | Cognitive Dysfunction | Anxiety | Loneliness | Treatment Adherence and Compliance | Mental Health Issue | Self Esteem | Interpersonal Relations | Functioning, Psychosocial | Social Functioning | Well-Being, Psychological | Functioning, Social

Netherlands
Fudan University

Recruiting

Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA

Colorectal Cancer Metastatic

China
Ain Shams University

Recruiting

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Diabetic Kidney Disease | Diabetic Nephropathies

Egypt
Diakonhjemmet Hospital
Karolinska University Hospital; Medical University of Vienna; Oslo University... and other collaborators

Not yet recruiting

Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM) (RA-DRUM)

Rheumatoid Arthritis

Austria, Sweden, Norway, United Kingdom
Taizhou Hospital

Not yet recruiting

Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell (SCLC)

SCLC | Maintenance Treatment
Applied Science & Performance Institute

Recruiting

Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine

Cognitive Change | Mood | Caffeine | Mood Change

United States
NYU Langone Health

Not yet recruiting

Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis

Acute Bronchiolitis

United States
Nicolaus Copernicus University in Toruń, Collegium...

Recruiting

The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.

Knee Osteoarthritis | Knee Injuries | ACL Injury

Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
Yale University
Usona Institute

Not yet recruiting

Open-Label Psilocybin

Safety, Feasibility, and Tolerability of Psilocybin Treatment in Individuals With Functional Impairment Due to Psychiatric Symptoms
University of California, San Francisco
Johns Hopkins University

Not yet recruiting

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis (PRISM-TB)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR

Peru, Vietnam, Moldova, Republic of, Mongolia, Pakistan, Philippines, South Africa
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Jeffrey Joseph
RTM Vital Signs, LLC

Recruiting

Wearable Wireless Respiratory Monitoring System That Detects and Predicts Opioid Induced Respiratory Depression

Respiratory Insufficiency | Clinical Deterioration

United States
Assiut University

Not yet recruiting

Iron Status in Autism Spectrum Disorders

Anemia, Iron Deficiency
Shanghai Municipal Hospital of Traditional Chinese...

Not yet recruiting

A Clinical Trial of Chazhu Xiaozhi Decoction Against Non-alcoholic Fatty Liver Disease

Hepatic Steatosis | Symptoms and Signs

China
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
University of Palermo

Recruiting

Effectiveness of Extracorporeal Shockwave Therapy and Nutraceutical Supplementation in the Treatment of Epicondylitis: a Clinical Trial

Tennis Elbow | Epicondylitis, Lateral | Epicondylitis of the Elbow

Italy
Seoul St. Mary's Hospital

Not yet recruiting

The Role of Intravenous Ferritin in Optimizing Postoperative Recovery Following Pancreaticoduodenectomy (Ferritin)

Pancreaticojuodenectomy
Taichung Veterans General Hospital
All Clean Health Co., Ltd

Not yet recruiting

The Effect of AC-134 in Chronic Kidney Diseases

Nephrology

Taiwan
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection
Copenhagen University Hospital at Herlev
Aarhus University Hospital; Rigshospitalet, Denmark

Recruiting

Benefit of Spectral Information in Patients Suspected for Lung Cancer

Lung Neoplasm Malignant

Denmark
Medical College of Wisconsin

Not yet recruiting

Puerto Rican Obesity Intervention for Men

Obesity

United States
University of Illinois at Chicago

Recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer (BRE-10)

Breast Cancer | HER2-positive Breast Cancer

United States

Search clinical trials for: first-line drugs

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