Search clinical trials for: moderate arthritis

Total 16481 results

Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB2 to Remicade® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Bulgaria, Lithuania
Kang Stem Biotech Co., Ltd.

Unknown

Long-term Safety and Efficacy of FURESTEM-CD Inj. in Patients With Moderately Active Crohn's Disease(CD)

Crohn's Disease

Korea, Republic of
Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Poland, United Kingdom
Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB5 to Humira® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Lithuania, Poland
UCB Italy s.p.a.

Completed

Open Label Study to Assess the Predictability of Early Response to Certolizumab Pegol in Patients With Rheumatoid Arthritis (SPEED)

Rheumatoid Arthritis

Italy
Centrexion Therapeutics

Completed

Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain

Osteoarthritis

United States
Hoffmann-La Roche

Completed

A Study of Tocilizumab + DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Italy
Hoffmann-La Roche

Completed

An Observational Study of Tocilizumab (Actemra) in Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Peru
Hoffmann-La Roche

Completed

A Study of the Effect of Tocilizumab on Markers of Atherogenic Risk in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Canada, Puerto Rico, United Kingdom
Hoffmann-La Roche

Completed

A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Brazil, United Kingdom, Canada, Argentina, Mexico, Austria, Israel, Colombia, Peru, Russian Federation, Philippines, Puerto Rico, Germany, Greece, Poland, Spain, France, Singapore, China, South Africa, Hungary, Denmark, Finlan... and more
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs

Rheumatoid Arthritis

Italy
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
Kunming Baker Norton Pharmaceutical Sales Co.,...

Unknown

Clinical Study of Artz in the Treatment of Knee Osteoarthritis (Artz)

Knee Osteoarthritis

China
ProCore Ltd.

Completed

A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis

Osteoarthritis

Israel
Amgen

Completed

Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Spain, Canada, Bulgaria, Russian Federation, Germany, Hungary, Poland, Czech Republic, Romania, United Kingdom
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees

Knee Osteoarthritis

United States
Amgen

Completed

Moderate Rheumatoid Arthritis (RA) With Etanercept (Enbrel)

Rheumatoid Arthritis

United States, Canada
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA19926 on the Safety of Tocilizumab (RoActemra/Actemra) in Participants With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

France
Invion, Inc.

Completed

Double-Blinded, Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Biochemical Activity of Intravenous Cpn10 Administration in Subjects With Mild to Moderate SLE.

Lupus Erythematosus, Systemic

United States
Catherine Buettner
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms

Pain | Weakness | HMG COA Reductase Inhibitor Adverse Reaction | Cramps | Myalgia or Myositis Nos

United States
Amgen

Completed

Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Canada, Germany, United Kingdom
Centrexion Therapeutics

Completed

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Osteoarthritis of the Knee

United States
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22762 to Evaluate Safety and Efficacy of Subcutaneous Tocilizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA).

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22763 and NA25220 of Subcutaneous RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Charleston Laboratories, Inc

Completed

A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip

Pain | Nausea | Vomiting

United States
Takeda

Completed

Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment

Gout | Moderate Renal Impairment

United States
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy

Rheumatoid Arthritis

France, Germany, Italy, Australia, United States, Canada, Mexico, United Kingdom, Sweden, Belgium, Switzerland, Netherlands, Puerto Rico, Iceland
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Early Moderate to Severe Rheumatoid Arthritis Who Completed Study WA19926

Rheumatoid Arthritis

Macedonia, The Former Yugoslav Republic of
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, China, United States, France, Sweden, South Africa, Czech Republic, Australia, Germany, Russian Federation, Canada, Thailand, Mexico, Hong Kong, Brazil, Argentina, Panama, Costa Rica, Finland
Hoffmann-La Roche

Withdrawn

A Study of The Effect of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate on Articular Damage in The Hand in Patients With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response to Non-Biological DMARDs

Rheumatoid Arthritis
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Indonesia
Genentech, Inc.

Completed

A Long-Term Extension Study of WA22762 and NA25220 of Subcutaneous (SC) Tocilizumab (TCZ) in Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Puerto Rico
Kang Stem Biotech Co., Ltd.

Completed

Safety of FURESTEM-RA Inj. in Patients With Moderate to Severe Rheumatoid Arthritis(RA) (RA)

Rheumatoid Arthritis

Korea, Republic of
Revive Therapeutics, Ltd.

Completed

Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout

Gout

United States
MedImmune LLC
MedImmune Ltd

Completed

A Study of Mavrilimumab in Subjects With Moderate-to-Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Bulgaria, Poland, Russian Federation, South Africa, Spain, Estonia, Hungary, Ukraine, Argentina, Chile, Germany, Serbia, Czech Republic, Colombia
Mundipharma Pte Ltd.
Mundipharma Korea Ltd; Mundipharma (Hong Kong) Ltd; Mundipharma Distribution...

Completed

Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain

Osteoarthritis | Rheumatoid Arthritis | Lower Back Pain | Joint Pain | Muscle Pain

Hong Kong, Korea, Republic of, Philippines
Hoffmann-La Roche

Completed

An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Australia
Mundipharma Pharmaceuticals Sdn. Bhd.

Completed

Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity

Osteoarthritis | Rheumatoid Arthritis | Lower Back Pain | Joint Pain | Muscle Pain

Malaysia
Pfizer

Completed

Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening

Rheumatoid Arthritis

Hungary, Qatar, Romania, Ukraine, China, Czech Republic, Malaysia, Thailand, Lebanon, South Africa, Philippines, Brazil, Colombia, Egypt, Jordan, Mexico, Russian Federation, Taiwan, United Arab Emirates
Hoffmann-La Roche

Completed

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Germany, Italy, Spain, United Kingdom, Hong Kong, United States, Colombia, Brazil, Canada, New Zealand, South Africa, Philippines, Russian Federation, Thailand, Singapore, Bulgaria, Mexico, Australia, Lithuania, Poland, Ar... and more
Stanford University

Completed

Web-based CBT for Symptoms of Mild-to-Moderate Anxiety and Depression in Youth With Chronic Illness

Depression | Systemic Lupus Erythematosus | Anxiety | Juvenile Idiopathic Arthritis | Inflammatory Bowel Disease
First Affiliated Hospital of Harbin Medical University
Shanghai Baiying Medical Technology Co., Ltd.

Unknown

Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis (ESIETNKOA)

Osteoarthritis Of Knee

China
Takeda

Terminated

VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis (VELVET)

Rheumatoid Arthritis

United States, Argentina, Canada, Czech Republic, Germany, Hungary, Italy, Mexico, Poland, Spain, United Kingdom
First Affiliated Hospital of Harbin Medical University
Shanghai baiying pharmaceutical technology Co., Ltd.

Unknown

Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis (EIAIETNKOA)

Osteoarthritis of Knee

China
Hoffmann-La Roche

Terminated

A Study of Ocrelizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Belgium, United Kingdom, Canada, New Zealand, Spain, Russian Federation, Australia, Netherlands
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary
AbbVie (prior sponsor, Abbott)
University Health Network, Toronto

Completed

Real Life Evaluation of Rheumatoid Arthritis in Canadians Taking HUMIRA (REACH)

Moderate-to-severe Rheumatoid Arthritis
Pfizer
Amgen

Completed

Open-Label Study Comparing Etanercept to Conventional Disease Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

Chile, Colombia, Argentina, Mexico, Panama

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