Search clinical trials for: tenofovir alafenamide

Total 1149 results

VA Office of Research and Development
Baylor College of Medicine

Completed

Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse

Cocaine Dependence

United States
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Azienda Ospedaliera Universitaria Senese
Catholic University of the Sacred Heart; Ospedale Policlinico San Martino; Azienda... and other collaborators

Unknown

Neurological Monitoring in Patients Switching From Dolutegravir Based Regimen to Bictegravir Based Regimen (DOBINeuro)

HIV-1-infection

Italy
Erasmus Medical Center
Gilead Sciences

Unknown

Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir Alafenamide (BACTAF)

Hiv | Renal Insufficiency,Chronic | Therapeutic Agent Toxicity

Netherlands
New Discovery LLC

Unknown

Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical Transmission

Hepatitis B, Chronic | Pregnancy Related

China
ADRIANO LAZZARIN, MD
Ministero della Salute, Italy

Unknown

Implication for Strategies of Long Term Control of Viral Replication in Patient With Primary HIV Infection (PHI). (P25-INACTION)

HIV-1-infection

Italy
Institut de Médecine et d'Epidémiologie Appliquée...

Unknown

Initiation of First-line Antiretroviral Treatment With TENOFOVIR ALAFENAMIDE - EMTRICITABINE - BICTEGRAVIR at the First Clinical Contact in France: Trial IMEA 055 - FAST (FAST)

HIV Seropositivity

France
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, United Kingdom, Switzerland, Germany, Canada, France, Belgium, Puerto Rico
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
Saskatchewan Health Authority - Regina Area
Gilead Sciences

Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Hepatitis C, Chronic | HIV/AIDS | Bone Diseases, Metabolic | Opioid Dependence | HIV-1-infection | HCV Coinfection | Buprenorphine Dependence | Methadone Dependence | Co-infection

Canada
Bausch Health Americas, Inc.
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of Methylnaltrexone (MNTX) for the Relief of Constipation

Advance Illness Patients With OIC

United States
Bausch & Lomb Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%

Inflammation | Conjunctivitis, Seasonal Allergic | Conjunctivitis, Giant Papillary

Korea, Republic of
University of California, San Diego
Gilead Sciences; University at Buffalo

Completed

Elvitegravir (EVG) Cerebrospinal Fluid (CSF) Pharmacokinetics in HIV-Infected Individuals

HIV

United States
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Thomas Jefferson University

Completed

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

Hyperglycemia | Cardiovascular Diseases | Metabolic Syndrome | Weight Gain | HIV-1-infection | Renal Function Abnormal

United States
Bin Du

Unknown

Trimethoprim/Sulfamethoxazole Combined With Caspofungin as First-line Therapy in PCP

Pneumocystis Pneumonia

China
Bausch & Lomb Incorporated
Synteract, Inc.

Completed

Lotemax® Gel 0.5% and Restasis 0.05% in Participants With Mild or Moderate Keratoconjunctivitis Sicca (Dry Eye Disease)

Keratoconjunctivitis Sicca

United States
National Taiwan University Hospital
Mackay Memorial Hospital; Chang Gung Memorial Hospital; Kaohsiung Medical University... and other collaborators

Unknown

Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide as Maintenance Treatment for HIV/HBV-coinfection

Bone Diseases | Kidney Injury | Chronic Hepatitis B in HIV Patient

Taiwan
Southeast University, China

Unknown

Study of Tenofovir Alafenamide Fumarate Tablets (TAF) in Blocking Mother-to-child Transmission of Hepatitis B Virus

Hepatitis B Virus | Mother to Child Transmission

China
Cristina Mussini

Unknown

Evaluating Inflammatory and Immunological Changes of HIV-positive Patients Switching to DTG Dual Regimen Compared to Those Switching to a Triple Drugs Regimen (B/F/TAF)

HIV Infections
The First Hospital of Jilin University

Unknown

A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) and Intolerant to Entecavir

HBV
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

TAF Switch in F3/4 CHB pt With Partial Response to NUC (ESTAB-AFPVR)

Hepatitis B | Fibrosis and Cirrhosis of Liver

Taiwan
The Catholic University of Korea

Unknown

Treatment Efficacy and Safety of TDF-TAF Switch Study in South Korea

Chronic Hepatitis b

Korea, Republic of
Gilead Sciences

Completed

Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected Adolescents

HIV

United States, South Africa
Gilead Sciences

Completed

Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults

HIV Infections | Acquired Immunodeficiency Syndrome | HIV-1

United States, Canada
Gilead Sciences

Completed

Efficacy of Tenofovir Alafenamide Versus Placebo Added to a Failing Regimen Followed by Treatment With Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Atazanavir in HIV-1 Positive, Antiretroviral Treatment-Experienced Adults

HIV Infections | Acquired Immunodeficiency Syndrome | HIV

United States, Thailand, Uganda, Dominican Republic, Russian Federation
Gilead Sciences

Completed

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment (Co-STARs)

HIV-1 Infection | HCV Infection

United States, Puerto Rico
Göteborg University

Completed

Tenofovir Alafenamide Fumarate (TAF) Effect on Residual Intrathecal Immune Activation

HIV

Sweden
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum

Malaria
IlDong Pharmaceutical Co Ltd

Unknown

Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver

Hepatitis B
Yonsei University

Unknown

Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance

Hepatitis B | Antiviral Drug Adverse Reaction
CONRAD
United States Agency for International Development (USAID); Agility Clinical...

Completed

PK and PD Study of Oral F/TAF for HIV Prevention

HIV

Dominican Republic, United States
St. Stephens Clinical Research

Completed

RIFT: Effect of Rifampicin on Plasma PK of FTC, TAF and Intracellular TFV-DP & FTC-TP (RIFT)

HIV

United Kingdom
National Institute of Allergy and Infectious Diseases...

Terminated

Emtricitabine/Tenofovir Alafenamide as Salvage ART

HIV

United States
Janssen Sciences Ireland UC

Completed

Relative Bioavailability and Food Effect for Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination

Healthy

Belgium
Technical University of Munich

Completed

Changes in Insulin Sensitivity in Healthy Volunteers Taking Tenofovir Alafenamide (TAF)-Containing Antiretroviral Medication (TAF-IR)

Insulin Resistance

Germany
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

The Compartmental Biology of HIV in the Male Genital Tract

Human Immunodeficiency Virus | Virus Shedding

United States
Asian Pacific Liver Center at Coalition of Inclusive...

Unknown

TAF Switch Study in Hepatitis B Monoinfection

Hepatitis B
Janssen Scientific Affairs, LLC

Completed

Study to Evaluate the Relative Bioavailability of Fixed-dose Combination Tablet Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) as a Whole Tablet, as a Split Tablet, and as Crushed Tablet in Healthy Adult Participants

Healthy

United States
Janssen Sciences Ireland UC

Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Healthy

Netherlands
University of North Carolina, Chapel Hill
Gilead Sciences

Completed

Dose Proportionality of TFV-DP After a Single Dose of GS-7340 in Women

Healthy

United States
University of Sao Paulo
Financiadora de Estudos e Projetos

Completed

Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic

Candidiasis, Oral | Stomatitis, Denture

Brazil
NPO International TRI Network
Duke Clinical Research Institute; European Cardiovascular Research Center

Unknown

Radial Artery Patency and Bleeding, Efficacy, Adverse evenT Trial (RAPandBEAT)

Percutaneous Coronary Intervention
Gilead Sciences

Completed

A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients

HIV Infections

United States
Institut de Recherche pour le Developpement
National Malaria Control Program, Benin; Ministry of Foreign Affairs, France; Institut des Sciences Biomédicales Appliquées, Bénin and other collaborators

Completed

Intermittent Preventive Treatment During Pregnancy in Benin

Malaria

Benin
Mayo Clinic

Recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
The First Affiliated Hospital of Dalian Medical...

Recruiting

Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC

Long-Term Effects Secondary to Cancer Therapy

China
The Fourth Affiliated Hospital of Zhejiang University...

Recruiting

Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease

Parkinson Disease

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients (HepBTer)

Chronic Hepatitis b

Netherlands
Samuel Lunenfeld Research Institute, Mount Sinai...

Recruiting

Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study

Postpartum Hemorrhage

Canada

3

Subscribe