Search clinical trials for: topping-off.

Total 994 results

Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 2b Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of KW-6002 (Istradefylline) for the Treatment of Parkinson's Disease in Patients Taking Levodopa (6002-009)

Parkinson's Disease

Japan
BackBeat Medical Inc
Massachusetts General Hospital; MLM Medical Labs GmbH; nabios GmbH

Active, not recruiting

Moderato System: A Double-Blind Randomized Trial Ver 1.1

Bradycardia | Atrioventricular Block | Hypertension Resistant to Conventional Therapy

Hungary, Austria, Poland, Czechia, Latvia, Belgium, Lithuania
University of British Columbia

Not yet recruiting

Parkinsonian Sutter

Parkinson's Disease Stutter
University of British Columbia

Not yet recruiting

A Phase 2 Trial of Deep Brain Stimulation for Spasmodic Dysphonia

Spasmodic Dysphonia

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Abbott Medical Devices

Terminated

Evaluation of Resynchronization Therapy for Heart Failure (EARTH)

Heart Failure

Canada
Sunovion

Completed

A Study of an Investigational Drug to See How it Affects the People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes) Compared to an Approved Drug Used to Treat People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes)

Motor OFF Episodes Associated With Parkinson's Disease

Spain, United Kingdom, Germany, Italy, Austria, France
Functional Neuromodulation Ltd

Active, not recruiting

ADvance II Study: DBS-f in Patients With Mild Alzheimer's Disease

Alzheimer Disease

United States, Canada, Germany
Hacettepe University

Unknown

Biodex Balance System Cut-off Scores in Geriatric Individuals

Low Back Pain | Balance; Distorted
Imperial College London
Asthma UK Centre for Applied Research

Active, not recruiting

Using Specific Tests in Preschool Children With Wheeze to Help us Determine the Necessity of Inhaled Corticosteroid Therapy (Feasibility Study). (TAILOR)

Wheezing

United Kingdom
Peking University Third Hospital

Completed

Sigmoid Take-off, New Rectum Definition

Rectal Cancer

China
Baxter Healthcare Corporation

Recruiting

Theranova Randomized, Controlled, Trial (RCT) in China

Acute Kidney Failure | Chronic Kidney Failure

China
Restor3D

Terminated

TKA Operating Room Efficiency for TKA Using Customized Implant Techniques

Osteoarthritis, Knee

United States
Washington University School of Medicine

Completed

Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses (CFO)

Diabetes Mellitus | Peripheral Neuropathy | Orthotic Device

United States
University of Aarhus
University of Miami; TrygFonden, Denmark

Active, not recruiting

A Pilot Study of OurRelationship.dk, a Web-based Self-help-Program for Couples With High Levels of Conflict or Distress

Family Relationship | Marital Conflict | Relationship Distress

Denmark
University Hospital Inselspital, Berne
Czech Technical University in Prague

Recruiting

SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease (EMO-SPEECH-PD)

Parkinson Disease

Switzerland, Czechia
Columbia University
National Institute on Aging (NIA); Harvard School of Public Health (HSPH); National...

Completed

The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia

Dementia | Alzheimer Disease | Prescribing, Off-Label

United States
Azienda Ospedaliera di Lecco

Unknown

Randomized Anticoagulation Trial in Opcab (RATIO) (RATIO)

Ischemic Heart Disease

Italy, China
Tan Tock Seng Hospital

Completed

Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot

Plantar Fasciitis | Achilles Tendinopathy | Insertional Achilles Tendinopathy | Metatarsalgia | Pes Cavus | Subtle Cavus Foot | Mechanical Foot Pains | Strain of Peroneal Tendon | Pes Cavus, Bilateral | Pes Cavovarus

Singapore
Medtronic Bakken Research Center
Medtronic

Terminated

CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation

Heart Failure | Atrial Fibrillation | Sudden Cardiac Death

Germany
Konkuk University Medical Center

Completed

Saline Bag and TEE During Cardiac Displacement

Ischemic Heart Disease

Korea, Republic of
Hospital Pitangueiras

Unknown

Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery

Coronary Artery Disease

Brazil
Marc Righini
University Hospital, Angers; University Hospital, Brest; Academisch Medisch Centrum...

Completed

Age-adjusted D-dimer Cut-off Levels to Rule Out Pulmonary Embolism (ADJUST)

Pulmonary Embolism

Switzerland, France, Netherlands
TriHealth Inc.

Terminated

The Effects of Sacral Neuromodulation for Urinary Urgency, Frequency, and Urge Incontinence

Urinary Urge Incontinence

United States
VA Office of Research and Development

Completed

ROOBY Trial Follow-up Extension

All Cause Mortality | MACE

United States
Karadeniz Technical University
Trabzon Kanuni Education and Research Hospital

Unknown

Acute Effects of Cell Phone Exposure on Immediate Attention Levels and Concentration of Emergency Physicians

Acute Effects of EMWs Emitted by Cell Phones

Turkey
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness (ORGAR)

Consciousness Disorders | Wearing Off Effect | Artificial Respiration

France
Moon Surgical

Completed

Maestro LIFT-OFF: Surgical Assistance Device in Abdominal Laparoscopic Surgery (Maestro)

Surgery

Belgium
Hospital San Carlos, Madrid

Completed

Safety and Efficacy of Medications COVID-19

Severe Covid-19

Spain
PureIMS B.V.
Cooperative Clinical Drug Research and Development AG (CCDRD AG)

Completed

A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops™ Relative to INBRIJA®

Parkinson Disease | Parkinson | Parkinson's Disease and Parkinsonism

Bulgaria
The Medicines Company

Completed

Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB (OPCAB)

Cardiac Surgery | Coronary Artery Bypass Surgery

United States
University of Oxford

Completed

Safety and Efficacy of the Alpha AMS Subretinal Implant (OX-RI)

Retinitis Pigmentosa

United Kingdom
Yonsei University

Recruiting

Effect of Non-anemic Iron Deficiency on Outcome Following Off-pump Coronary Revascularization

Coronary Artery Bypass, Off-Pump | Iron Deficiencies

Korea, Republic of
Organogenesis

Completed

Pivotal Trial of Dermagraft(R) to Treat Diabetic Foot Ulcers

Diabetic Foot Ulcer

United States
Washington University School of Medicine
University of Pittsburgh; American Glaucoma Society

Recruiting

Tied Tube Trial in Glaucoma Surgery

Glaucoma Eye | Ahmed Glaucoma Valve Implantation

United States
Yonsei University

Completed

Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft

Postoperative Acute Kidney Injury After Off-pump Coronary Artery Bypass Graft

Korea, Republic of
Copenhagen University Hospital, Hvidovre

Recruiting

Endoscopic Step-up Approach vs Aggressive Debridement of Large Pancreatic Walled-off Necrosis

Pancreatitis, Acute Necrotizing | Pancreatic Necrosis

Denmark
Icahn School of Medicine at Mount Sinai

Unknown

Safety and Effectiveness of Corneal Crosslinking (CXL): Keratoconus and Post-Refractive Ectasia (CXL)

Keratoconus | Ectasia

United States
University of Oxford

Unknown

SyncAV Study: Investigation of the Efficacy of the SyncAV Fusion Pacing Algorithm on Exercise

Heart Failure, Systolic

United Kingdom
Keimyung University Dongsan Medical Center

Unknown

Heated Circuit on Sore Throat

General Anesthesia
Kim Houlind

Completed

The Danish On-pump, Off-pump Randomization Study (DOORS)

Ischemic Heart Disease

Denmark
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Terminated

An Extension of Istradefylline in North American Parkinson's Disease Patients Who Have Completed Study 6002-INT-001

Parkinson's Disease

United States
Kyowa Kirin, Inc.
Kyowa Hakko Kirin UK, Ltd.

Completed

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

Parkinson's Disease

United States
Kyowa Kirin Co., Ltd.

Completed

Long-Term Safety Study of KW-6002 (Istradefylline) in Parkinson's Disease Patients (6002-010)

Parkinson's Disease

Japan
Boston Scientific Corporation

Completed

AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study

Walled Off Pancreatic Necrosis

United States
American Society of Clinical Oncology
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; Merck Sharp & Dohme LLC; Pfizer; AstraZene... and other collaborators

Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Advanced Solid Tumors

United States
Kyowa Kirin, Inc.

Completed

12-Week, Double-Blind, Placebo-Controlled Study of 20 and 60 mg/Day Istradefylline in Parkinson's Disease Patients on Levodopa/Carbodopa

Parkinson's Disease

United States
Janssen Research & Development, LLC

Completed

A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder

Bipolar Disorder

United States
University of Saskatchewan

Unknown

Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF (MUF)

Coronary Artery Disease | Anemia

Canada

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