Search clinical trials for: severe co-morbidity,

Total 25487 results

University Hospital Freiburg
Pfizer

Completed

Ziprasidone for Severe Conduct and Other Disruptive Behavior Disorders

Conduct Disorder | Oppositional Defiant Disorder

Germany
All India Institute of Medical Sciences, New Delhi

Completed

Effect of Addition of Oral Montelukast to Standard Treatment in Acute Moderate to Severe Asthma in Children (Montelukast)

Bronchial Asthma

India
University of Aarhus

Unknown

Cortical Excitability in Patients With Severe Brain Injury

Subarachnoid Hemorrhage | Anoxic Brain Injury | Severe Traumatic Brain Injury

Denmark
University of Aarhus

Unknown

Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.

Craniocerebral Trauma | Traumatic Brain Injury | Subarachnoid Hemorrhage | Anoxic Brain Injury

Denmark
University of Aarhus
Aarhus County, Denmark

Completed

Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Traumatic Brain Injury.

Craniocerebral Trauma | Traumatic Brain Injury | "Rehabilitation"

Denmark
The Back Research Center, Denmark

Completed

The Efficacy of Active Conservative Treatment for Patients With Severe Sciatica. A Randomized Clinical Controlled Trial

Sciatica

Denmark
Abbott Medical Devices

Completed

Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study)

Stroke | Atherosclerosis | Carotid Stenosis | Carotid Artery Disease
The University of New South Wales
Australian Government Department of Health and Ageing

Completed

Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study

Behavior, Addictive | Obesity | Psychotic Disorder

Australia
The Cleveland Clinic

Completed

A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction

Acute Myocardial Infarction

United States
Johns Hopkins University

Completed

Phase II Study of High-Dose Cyclophosphamide in Patients With Severe Autoimmune Hematologic Disease

Autoimmune Diseases | Purpura, Thrombocytopenic | Anemia, Hemolytic, Autoimmune | Felty Syndrome

United States
Wayne State University

Unknown

Intravenous Terbutaline in Severe Status Asthmaticus

Status Asthmaticus

United States
University Hospital, Bonn
Universitätsmedizin Mannheim

Withdrawn

Fetoscopic Tracheal Balloon Occlusion in Unborns With Severe Congenital Diaphragmatic Hernia - EUROTRIAL I

Diaphragmatic Hernia

Germany
Government Medical College Srinagar
Government Psychiatric Diseases Hospital, Srinagar

Completed

Use of Electroconvulsive Therapy (ECT) in Chronic, Severe, Treatment Resistant Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

India
University Hospital, Geneva
Pamukkale University; Hospices Civils de Lyon; Hospital Clinic of Barcelona; German... and other collaborators

Unknown

Preop Hemodialysis or Intraop Ultrafiltration for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery (SeRenaD-CPB)

Cardiovascular Disease | Non-Dialysis Dependent Severe Renal Dysfunction

Germany, France, Spain, Switzerland, Turkey
Pfizer

Completed

Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients

Arthritis, Rheumatoid

Canada, United States
Abbott

Completed

Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis (CHAMPION)

Psoriasis

United States
Florence Nightingale Hospital, Istanbul

Completed

Velocity Vector Imaging in Patients With Moderate-to-Severe Aortic Regurgitation

Aortic Regurgitation

Turkey
St. Jude Children's Research Hospital

Completed

Treatment of Severe Osteogenesis Imperfecta by Allogeneic Bone Marrow Transplantation

Osteogenesis Imperfecta

United States
Chulalongkorn University
Allergan

Unknown

Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes

Dry Eye

Thailand
Sanofi

Completed

Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).

Chronic Heart Failure

Canada, United States, United Kingdom
Memorial Medical Center

Terminated

A Prospective, Randomized Trial of Early Versus Late Tracheostomy in Trauma Patients With Severe Brain Injury

Respiratory Failure | Traumatic Brain Injury

United States
University of Oxford
Wellcome Trust; Mahidol University

Unknown

A Randomized Double Blinded Comparison of Ceftazidime and Meropenem in Severe Melioidosis (ATOM)

Melioidosis

Thailand
Movetis

Completed

Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation

Chronic Constipation
Ministry of Health, China

Unknown

Wingspan Stenting for Symptomatic Severe Stenosis of Intracranial Atherosclerosis Registry in China (WingspanSSIR)

Intracranial Atherosclerosis

China
National University Hospital, Singapore

Unknown

External Micropulse Diode Laser Transscleral Trabeculoplasty (EMDLT) for Severe Open Angle Glaucoma (EMDLT)

Primary Open Angle Glaucoma

Singapore
Tehran University of Medical Sciences
Hoffmann-La Roche

Completed

Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease

Behcet's Syndrome

Iran, Islamic Republic of
Fred Hutchinson Cancer Center
University of California, Los Angeles; Oregon Health and Science University; Ohio... and other collaborators

Completed

Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor

Anemia, Aplastic

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ReFacto AF in Severe Hemophilia A

Hemophilia A
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

Inhaled Tacrolimus, Add-on to Inhaled Corticosteroids & Long Acting B2 Agonists in Moderate to Severe Persistent Asthma

Asthma, Bronchial | Bronchial Asthma

Russian Federation, Poland, Germany, Ukraine, Czech Republic
LivaNova

Completed

Clinical Evaluation on Advanced Resynchronization

Heart Failure | Cardiomyopathy

Netherlands, France, Spain, Italy, Germany, United Kingdom
Dalhousie University
Canadian Institutes of Health Research (CIHR)

Unknown

Problems With Morphine Use in Patients With a Severe Brain Injury

Subarachnoid Hemorrhage | Head Trauma | Close Head Injury

Canada
Abbott

Completed

Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severely Active Psoriatic Arthritis Subjects With Inadequate Response to Disease Modifying Anti-Rheumatic Drug Therapy

Arthritis | Psoriatic
Abbott

Completed

Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Federico II University

Completed

Replacement GH Therapy After Bariatric Surgery in Patients With Very Severe Obesity (GH&LASGB)

Obesity | GHD

Italy
Abbott

Completed

Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis

Arthritis | Psoriatic
Abbott

Completed

Extension Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Abbott

Completed

Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Abbott

Completed

Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Light Chain Bioscience - Novimmune SA

Completed

NI-0401 in Active Crohn's Disease

Moderate to Severe Crohn's Disease
National Institute of Allergy and Infectious Diseases...

Completed

Emergency Use of Voriconazole in Patients With Life-Threatening Invasive Fungal Infections

Mycoses

United States
National Cancer Institute (NCI)

Completed

Randomized Double-Blind Placebo-Controlled Trial Using Recombinant Human Interleukin-10 for Moderate-to-Severe Psoriasis

Psoriasis

United States
National Cancer Institute (NCI)

Completed

Micellar Paclitaxel to Treat Severe Psoriasis

Psoriasis

United States
National Institute of Diabetes and Digestive and...

Completed

Leptin to Treat Severe Insulin Resistance - Pilot Study

Syndrome

United States
National Institute of Diabetes and Digestive and...

Completed

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia

Beta Thalassemia

United States
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Severe Combined Immunodeficiency

United States
National Institute of Arthritis and Musculoskeletal...

Completed

Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy

Arthritis, Rheumatoid | Synovitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Interleukin-12 in the Treatment of Severe Nontuberculous Mycobacterial Infections

Atypical Mycobacterium Infection

United States
French National Agency for Research on AIDS and...

Unknown

Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis

Fibrosis | Hepatitis C, Chronic

France
Pediatrix

Completed

Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia

Jaundice | Hyperbilirubinemia

United States
IRCCS San Raffaele
Fondazione Telethon

Completed

Gene Therapy for ADA-SCID

Severe Combined Immunodeficiency Syndrome

3

Subscribe