Search clinical trials for: signal pathway

Total 2609 results

Shaare Zedek Medical Center

Completed

The Clinical Impact of Isolation of Two Different Bacteria in Urinary Cultures

Urinary Tract Infection
Medical Center Alkmaar

Unknown

Dipeptide Alanyl Glutamine and Postoperative Insulin Resistance in Colon Carcinoma Patients (AIRCo)

Colon Carcinoma

Netherlands
Vanderbilt University
National Institutes of Health (NIH)

Terminated

Effects of PA-1 Transcriptional Regulation on Monocyte Function

Atherosclerosis

United States
Vanderbilt University

Terminated

Characterizing PAI-1 Modulation on Monocyte Adhesion

Atherosclerosis

United States
University of Iceland
The Icelandic Parkinson´s Association.; Icelandic Physiotherapy Association

Completed

The Effect of High-Volume Walking With Visual Cues (VC) in Parkinson´s Disease (PD)

Parkinson´s Disease

Iceland
INSYS Therapeutics Inc

Completed

Study to Determine the Maximum Tolerated Dose of LErafAON in Patients With Advanced Cancer

Neoplasms

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Carcinoma of Unknown Primary

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Brain and Central Nervous System Tumors

United States
vTv Therapeutics
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA)

Coagulation

United States
Sheba Medical Center

Completed

Evaluation of Dorsal Visual Stream in Patients With Schizophrenia

Schizophrenia

Israel
University Medical Centre Ljubljana
Hyb, d.o.o., Slovenia

Completed

Clinical Investigation of Wireless Transmission of Invasive Blood Pressure Signal

Shock | Atrial Fibrillation | Multiple Trauma | Perioperative/Postoperative Complications
Progen Pharmaceuticals

Terminated

Phase III Study of PI-88 in Post-resection Hepatocellular Carcinoma (PATHWAY)

Cancer | Hepatocellular Carcinoma | Primary Liver Cancer | Liver Cancer | Hepatoma

Hong Kong, Singapore, United States, Australia, Canada, Italy, Malaysia, Spain, Taiwan, Thailand
SciClone Pharmaceuticals

Terminated

Phase II Study to Evaluate Efficacy and Safety of RP101 in Combination With Gemcitabine (RP101)

Pancreatic Cancer

United States, Chile, Spain, Brazil, Argentina, France, Germany, Hungary, Netherlands, Peru, Poland, Romania, United Kingdom
Radboud University Medical Center
Maastricht University Medical Center

Completed

Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental Endotoxemia (VIHE)

Endotoxemia

Netherlands
Samsung Medical Center

Unknown

Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug Metabolis/Transport Pharmacogenetics in the Prediction of Response and Treatment Outcomes in Acute Myeloid Leukemia

Patients With Acute Myeloid Leukemia | Patients Receiving Induction/Consolidation Chemotherapy

Korea, Republic of
Guangzhou University of Traditional Chinese Medicine

Completed

Establishment and Evaluation to the Effects of a Clinical Pathway for Acute Ischemic Stroke (PAIS)

Acute Ischemic Stroke

China
AviGenics

Completed

Safety and Efficacy Study of GCSF Therapy to Treat Patients at High Risk for Chemotherapy Induced Severe Neutropenia

Breast Cancer | Neutropenia

United States, India
Beijing Children's Hospital
Merck Sharp & Dohme LLC

Unknown

Leukotrienes Pathway in Chinese Children With Sleep-disordered Breathing

Sleep-disordered Breathing

China
Tel-Aviv Sourasky Medical Center
Rabin Medical Center

Unknown

DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)

Silicosis

Israel
University of Sao Paulo

Unknown

Levonorgestrel-releasing Intrauterine Device on Obese Women: Effects on Hemostatic and Arterial Function

Obesity | Contraception Desired

Brazil
Assistance Publique - Hôpitaux de Paris
Institut de Recherches Scientifiques sur les Boissons

Completed

Does the Threat of an Aversive Reaction Affect Craving of Alcohol During Cue Exposure in Alcohol Dependent Patients?

Alcoholic Intoxication, Chronic

France
Mayo Clinic

Completed

Development of a Hospital Service That Uses Critical Pathway (Protocolized) Care Plans to Provide High-Quality, High-Reliability, Evidence-Based Medical Care

Critical Pathways

United States
Sahlgrenska University Hospital, Sweden

Completed

Microembolic Signals and Serum Markers of Neuronal Damage During Transcatheter Aortic Valve Implantation.

Aortic Stenosis

Sweden
Roswell Park Cancer Institute

Completed

Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer

Lymphoma | Brain and Central Nervous System Tumors | Neuroblastoma | Retinoblastoma

United States
University College Cork
Science Foundation Ireland; American Neurogastroenterology and Motility Society

Unknown

An Assessment of Cognitive Function in Irritable Bowel Syndrome

Irritable Bowel Syndrome

Ireland
BSP Biological Signal Processing Ltd.

Unknown

Feasibility of High Frequency QRS Analysis in Patients With Acute Myocardial Infarction

Myocardial Infarction

Israel
Pfizer

Completed

Genotropin Study Assessing Use of Injection Pen

Growth Hormone Deficiency | Idiopathic Short Stature

United States
Isfahan University of Medical Sciences

Completed

Effect of Oral L-carnitine Supplement on Lipid Profile, Anemia, and Quality of Life of Patients

Complication of Hemodialysis

Iran, Islamic Republic of
University of Aarhus

Completed

Effects of Fasting and Exercise on Insulin and GH Signaltransduction in Muscle and Fat (FEIGH)

Healthy

Denmark
National Taiwan University Hospital

Completed

Dissection of Differentially Expressed Genes and Pathways in Patients With OSAS Before and After CPAP Treatment

Sleep Apnea, Obstructive

Taiwan
Austin Health
Royal North Shore Hospital; Ballarat Health Services; Queen Elizabeth Hospital...

Unknown

Dual Inhibition of EGFR Signalling Using the Combination of Cetuximab and Erlotinib (Dux)

Metastatic Colorectal Cancer

Australia
Green Signal Biopharma Private Limited

Completed

A Study of Comparing Safety and Reactogenicity, of Lyophilized BCG Vaccine IP of Green Signal Bio Pharma Private Limited, India With BCG Vaccine of Serum Institute of India Limited in 120 Healthy Children.

Healthy

India
Hospital Clinic of Barcelona

Unknown

Effect of Maraviroc (MCV) on the Immunological Recovery of HIV-1 Discordant Patients With CD4 Lymphocyte Counts Below 200 Cells/mm3 (DIS-MVC)

HIV-1 Infection

Spain
Centers for Disease Control and Prevention
Columbia University; United States Agency for International Development (USAID)

Completed

Ethiopia Malaria Therapeutic Efficacy Study

Malaria

Ethiopia
University of Aarhus
MR Research Center, Skejby Sygehus, Brendstrupgaardsvej 100, 8200 Aarhus N

Terminated

Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism

Hypothyroidism

Denmark
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Remote Ischaemic Preconditioning in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Washington

Unknown

Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone

Substance-Related Disorders

United States
Novartis

Completed

Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet

Hypertension

United States
Aarhus University Hospital

Completed

Peripheral Effects of Endotoxin on Insulin Resistance

Healthy

Denmark
Wolfson Medical Center

Unknown

Combined Treatment With Fresh Frozen Plasma and Rituximab (Mabthera) in Patients With Advanced Refractory Chronic Lymphocytic Leukemia

Advanced Refractory Chronic Lymphocytic Leukemia

Israel
National Institute of General Medical Sciences...

Unknown

Critical Illness Outcomes Study (CIOS)

Critical Illness | Intensive Care Unit | Intensive Care

United States
University of Edinburgh
NHS Lothian; British Heart Foundation

Completed

Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation

Heart Failure | Heart Disease | Vasodilatation

United Kingdom
Changhai Hospital
National Natural Science Foundation of China

Completed

PD-1/PD-L1 Pathway Study on Septic Patients

Sepsis
Aristotle University Of Thessaloniki
Greek State Scholarship Foundation

Completed

Evaluation Of Patients With Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) Based on Nonlinear Analysis Of Respiratory Signals

Obstructive Sleep Apnea Syndrome (OSAS)

Greece
Hospital Authority, Hong Kong
The University of Hong Kong

Unknown

Chemoprevention of Gastric Cancer by Intervention With Helicobacter Pylori and Cyclooxygenase Pathway

Stomach Neoplasms

China
University Medical Center Groningen

Unknown

Paracrine Mechanisms of Bone Marrow Stem Cell Signalling in Chronic Heart Failure (BM-CHF)

Heart Failure

Netherlands, Italy
Tel-Aviv Sourasky Medical Center

Unknown

Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air

Lung Diseases
Seoul National University Hospital

Unknown

Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block (park001)

Complex Regional Pain Syndrome

Korea, Republic of
Universidad Complutense de Madrid

Unknown

Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers

Diabetic Foot Ulcers | Diabetic Foot | Osteomyelitis

Spain

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