Clinical Trials Sponsored by Pennine Acute Hospitals NHS Trust

Total 3087 results

CCTU- Cancer Theme
Breast Cancer Now; CRUK Cambridge Institute

Recruiting

Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible (Neo-RT)

Breast Cancer

United Kingdom
University Hospitals Bristol and Weston NHS Foundation...
University College, London; The Tuberous Sclerosis Association

Active, not recruiting

Acceptance and Commitment Therapy in Tuberous Sclerosis Complex (ACT in TSC)

Tuberous Sclerosis Complex

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia; Dynamic Metrics Ltd

Completed

Modelling and AI Using Sensor Data to Personalise REHABilitation Following Joint Replacement (MAPREHAB)

Arthroplasty Complications

United Kingdom
Oxford University Hospitals NHS Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Completed

Regional Lung Imaging Using Hyperpolarized Xenon Gas

Lung Disease

United Kingdom
University of Exeter
Medical Research Council; University Hospitals Bristol and Weston NHS Foundation... and other collaborators

Withdrawn

Facilitating Catheter Guidance to Optimal Site for VT Ablation (CPS)

Post-myocardial Infarction Ventricular Tachycardia

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; University of Birmingham

Withdrawn

A Feasibility Study of the SNUBY®, a Skin-to-skin Garment, in the Preterm Infant (Preterm SNUBY®)

Premature Birth | Breast Feeding
Michael Reddington
National Institute for Health Research, United Kingdom

Completed

Physiotherapy for Sciatica; Is Earlier Better? (POLAR)

Low Back Pain | Sciatica | Radiculopathy
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Osteoporosis Society; Orthopaedic Research UK

Completed

The Effects of Obesity on Bone Structure and Strength

Obesity | Osteoporosis

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; National Institute for Health Research...

Completed

Trial of a Medical and Mental Health Unit for Older People (TEAM)

Delirium | Confusion | Cognitive Impairment | Dementia

United Kingdom
King's College London
King's College Hospital NHS Trust; Charles University, Czech Republic; Hopital... and other collaborators

Recruiting

Biology of Juvenile Myoclonic Epilepsy (BIOJUME)

Juvenile Myoclonic Epilepsy

United States, Canada, Czechia, Denmark, Estonia, France, Italy, Norway, United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; IntraOp Medical Corporation; PLANETS Cancer Charity

Active, not recruiting

Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial (ELECTRA)

Locally Advanced Rectal Cancer | Locally Recurrent Rectal Cancer

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
British Eye Research Foundation, operating as Fight for Sight

Completed

EFFECT:Eccentric Fixation From Enhanced Clinical Training (EFFECT)

Age Related Macular Degeneration (ARMD)

United Kingdom
King's College London
King's College Hospital NHS Trust; Michael J. Fox Foundation for Parkinson's...

Withdrawn

Molecular and Functional Imaging in SNCA, Parkin and PINK1

Parkinson Disease | PARK1 | PARK2
University of Oxford
Imperial College Healthcare NHS Trust; Fortius Clinic; BUPA Cromwell Hospital...

Unknown

Predicting Osteoarthritis Risk Following Knee Injury. (KICK)

Osteoarthritis | Injury

United Kingdom
King's College London
King's College Hospital NHS Trust; National Institute for Health Research,...

Unknown

Development of King's College Hospital Breathlessness Service

Breathless Patients With Any Established Underlying Medical Diagnosis

United Kingdom
King's College Hospital NHS Trust
Leukemia Research Fund; Department of Health; Elimination of Leukaemia Fund

Unknown

Lentivirus Transduced Acute Myeloid Leukaemia Blasts Expressing B7.1 (CD80) and IL-2 (RFUSIN2-AML1)

Leukemia, Myeloid, Acute

United Kingdom
Queen Mary University of London
Oslo University Hospital; Rigshospitalet, Denmark; Barts & The London NHS Trust; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Completed

Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy (iTACTIC)

Hemorrhage | Trauma | Coagulopathy

Norway, Netherlands, United Kingdom, Denmark, Germany
Fondazione Poliambulanza Istituto Ospedaliero
Hospices Civils de Lyon; Fondazione Policlinico Universitario Agostino Gemelli... and other collaborators

Completed

Role of AI in CE for the Identification of SB Lesions in Patients With Small Intestinal Bleeding. (ArtIC)

Iron Deficiency Anemia | Obscure Gastrointestinal Bleeding

Italy
Cambridge University Hospitals NHS Foundation Trust
Juvenile Diabetes Research Foundation; Wellcome Trust; University of Cambridge; National Institute for Health Research, United Kingdom

Completed

Regulatory T Cells in Type 1 Diabetes Patients Treated With IL-2 (DILT1D)

Type 1 Diabetes

United Kingdom
King's College London
King's College Hospital NHS Trust; National Institute for Health Research,...

Terminated

Liver Immunosuppression Free Trial (LIFT)

Transplantation, Liver

United Kingdom
Institute of Cancer Research, United Kingdom
Cancer Research UK; University Hospital Birmingham NHS Foundation Trust

Unknown

Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours (111)

Stage I Testicular Non-Seminomatous Germ Cell Tumor

United Kingdom
Grace Ward
Guy's and St Thomas' NHS Foundation Trust; Royal Berkshire Hospital

Unknown

The Ecological Role of Yeasts in the Human Gut (YIG)

Irritable Bowel Syndrome | Inflammatory Bowel Diseases | Gastrointestinal Disease

United Kingdom
Barts & The London NHS Trust
Harvard Medical School (HMS and HSDM); Brigham and Women's Hospital

Unknown

Neurosurgical Transitional Care Programme (TCP)

Brain Diseases | Spinal Diseases | Brain Cancer | Brain Tumor | Surgery | Spinal Stenosis | Aneurysm | Fusion of Spine | Brain Metastases | Spinal Fusion | Trigeminal Neuralgia | Brain Tumor, Recurrent | Hydrocephalus | Spinal Cord Neoplasms | Brain Lesion | SPINAL Fracture | Brain Pathology | Spinal Instability | Spinal Curvature | Chiari; Net and other conditions

United Kingdom
Gene Signal SAS
Moorfields Eye Hospital NHS Foundation Trust; Johannes Gutenberg University... and other collaborators

Unknown

Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG (STRONG)

Neovascular Glaucoma | Ischaemic Central Retinal Vein Occlusion
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; Dystrophic Epidermolysis Bullosa Research Association...

Enrolling by invitation

Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa

Junctional Epidermolysis Bullosa | Laryngo Onycho Cutaneous Syndrome

United Kingdom
Papworth Hospital NHS Foundation Trust
Roche Pharma AG; National Institute for Health Research, United Kingdom

Completed

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension (TRANSFORM-UK)

Pulmonary Arterial Hypertension

United Kingdom
pSiMedica Limited
Singapore General Hospital; Guy's and St Thomas' NHS Foundation Trust; pSiOncology...

Unknown

32P BioSiliconTM in Addition to Gemcitabine in Pancreatic Cancer

Pancreatic Cancer

Singapore, United Kingdom
University of Oxford
Pfizer; Belfast Health and Social Care Trust; Queen's University, Belfast; Saint... and other collaborators

Completed

MEK and MET Inhibition in Colorectal Cancer (MErCuRIC1)

Colorectal Cancer | Solid Tumor

United Kingdom
University Hospital Schleswig-Holstein
Johannes Gutenberg University Mainz; Great Ormond Street Hospital for Children...

Completed

Endomicroscopy, IBS and Food Intolerance

Food Intolerance | Inflammatory Bowel Syndrome | Endomicroscopy

Germany
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Recruiting

SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study

Dental Caries in Children

United Kingdom
Anglia Ruskin University
University of Manchester; Pharmacy Research UK; Ashford and St. Peter's Hospitals...

Not yet recruiting

Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1 (DRP-EDiT)

Medication Administered in Error | Medication Adverse Effects | Medication Reaction
University Hospitals Coventry and Warwickshire...
University of Leeds; University of Manchester; University of Warwick

Recruiting

Reducing Colonoscopies in Patients Without Significant Bowel Disease (RECEDE)

Colorectal Cancer | Colorectal Disorders | Colorectal Adenoma | Colorectal Polyp

United Kingdom
CCTU- Cancer Theme
AstraZeneca; Cancer Research UK; University of Cambridge

Recruiting

WIRE - Novel Treatments in Renal Cell Cancer (WIRE)

Renal Cell Cancer

United Kingdom
Nottingham University Hospitals NHS Trust
Newcastle University; University of Kansas; Macmillan Cancer Support; Bishop Grosseteste...

Terminated

Nutrition Health Literacy of Cancer Patients and Their Support Networks. (NiiCproject)

Cancer | Oncologic Disorders | Nutrition Aspect of Cancer | Haematological Malignancy

United Kingdom
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Completed

Selenium for Musculoskeletal Health

Osteoporosis

United Kingdom
Julie Dawson
University of East Anglia; GN Otometrics

Completed

Accuscreen Equipment Evaluation For Newborn Hearing Screening

Hearing Loss

United Kingdom
University of East Anglia
Norfolk and Norwich University Hospitals NHS Foundation Trust; British Medical...

Unknown

Nitrite in Hypertrophic Cardiomyopathy (HCM) Study

Cardiomyopathy, Hypertrophic

United Kingdom
University of Oxford
Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston...

Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Malaria,Falciparum

United Kingdom
Nottingham University Hospitals NHS Trust
CICbioGUNE; Christian-Albrechts-University of Kiel; University of Veterinary...

Not yet recruiting

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity (GenMalCarb)

Irritable Bowel Syndrome (IBS) | Sucrase Isomaltase Deficiency
South Glasgow University Hospitals NHS Trust
Cardiff University; University of Bristol; University of Glasgow; Parkinson's UK

Active, not recruiting

Parkinson's Repository of Biosamples and Network Datasets (Tracking Parkinson's) (PRoBaND)

Parkinson's Disease

United Kingdom
University of Liverpool
Cancer Research UK; Liverpool University Hospitals NHS Foundation Trust; Advaxis... and other collaborators

Terminated

Safety Study of Recombinant Listeria Monocytogenes(Lm)Based Vaccine Virus Vaccine to Treat Oropharyngeal Cancer (REALISTIC:)

HPV-16 +ve Oropharyngeal Carcinoma

United Kingdom
Ospedali Riuniti Ancona
The University of Hong Kong; Yale University; The Leeds Teaching Hospitals NHS...

Completed

Objective and Subjective Outcomes of an Electronic Chest Drainage System

Lung Cancer

Italy
Cambridge University Hospitals NHS Foundation Trust
Medical Research Council; National Institute for Health Research, United Kingdom

Recruiting

Gaucherite - A Study to Stratify Gaucher Disease (Gaucherite)

Gaucher Disease, Type III | Gaucher Disease, Type I

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Alexion Pharmaceuticals...

Completed

Characterisation of Adult-Onset Hypophosphatasia

Hypophosphatasia

United Kingdom
St George's, University of London
University of Oxford; University Hospitals Bristol and Weston NHS Foundation...

Completed

Immunising Mums Against Pertussis 3 (iMAP3)

Whooping Cough | Immunization; Infection | Maternal Vaccine Exposure

United Kingdom
York Teaching Hospitals NHS Foundation Trust
University of York; University of Salford; York St John University

Completed

York Study of Unloading Shoes for Vascular Intermittent Claudication (YORVIC)

Peripheral Arterial Disease | Intermittent Claudication

United Kingdom
Ospedali Riuniti Ancona
The University of Hong Kong; Yale University; The Leeds Teaching Hospitals NHS...

Withdrawn

Effect of Regulated Pleural Pressure on Air Leak and Fluid Drainage Following Pulmonary Resections: A Multicenter Randomized Trial

Lung Cancer

Italy
Quadram Institute Bioscience
Norfolk and Norwich University Hospitals NHS Foundation Trust; Top Institute...

Completed

Gastric Layering Study

Healthy Volunteers

United Kingdom
Al-Quds University
Assiut University; Tanta University; Papworth Hospital NHS Foundation Trust; European... and other collaborators

Recruiting

Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy

Post Operative Pain

Italy, Egypt, United Kingdom, Palestinian Territory, occupied

Clinical Trials Sponsored by Pennine Acute Hospitals NHS Trust

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CROs in Bahrain

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