Search clinical trials for: Metformin ER

Total 2835 results

National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Recurrent Bladder Urothelial Carcinoma | Recurrent Renal Pelvis Urothelial Carcinoma | Recurrent Ureter Urothelial Carcinoma and other conditions

United States
Janssen Research & Development, LLC

Completed

A Study of Lazertinib (JNJ-73841937) in Healthy Participants

Healthy

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Type 2 Diabetes Mellitus
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants

Healthy Subjects
Baylor College of Medicine

Enrolling by invitation

Post-operative Pain Management in Children With Supracondylar Humerus Fractures

Supracondylar Humerus Fracture

United States
H. Lee Moffitt Cancer Center and Research Institute
Pediatric Cancer Foundation

Completed

Metformin in Children With Relapsed or Refractory Solid Tumors

Solid Tumors | Primary Brain Tumors

United States
MedSIR
Novartis

Recruiting

Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients (METALLICA)

Breast Cancer

Spain
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

Type 2 Diabetes Mellitus
Instituto Brasileiro de Osteopatia

Completed

Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders

Temporomandibular Disorder

Brazil
Roswell Park Cancer Institute

Completed

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

United States
Bristol-Myers Squibb

Completed

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Healthy Participants

United States
Weill Cornell Medical College in Qatar
University of Hull; Hamad Medical Corporation; Sidra Medical and Research Center

Active, not recruiting

HbA1c Variability in Type II Diabetes

Diabetes Mellitus Type 2

Qatar
Boehringer Ingelheim

Completed

DIA_CENTRAL:T2D Treatment Pattern in Central Europe

Diabetes Mellitus, Type 2

Bulgaria, Czechia, Hungary, Poland, Russian Federation
Sanofi

Completed

Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (SWITCH)

Type 2 Diabetes Mellitus

China
ARKAY Therapeutics
Albany Medical College

Not yet recruiting

Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients (RESILIENCE)

Obesity | Arthritis | Type 2 Diabetes | High Blood Pressure

United States
University of Minnesota
University of Colorado, Denver; Northwestern University; Olive View-UCLA Education... and other collaborators

Completed

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

Covid19 | SARS-CoV Infection

United States
Altimmune, Inc.

Completed

ALT-801 DDI Study in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

Australia
Peking Union Medical College Hospital
Chinese Academy of Sciences

Unknown

Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

Type2 Diabetes Mellitus

China
Eli Lilly and Company

Terminated

A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM) (IMPERIUM)

Diabetes Mellitus, Type 2

United States, Puerto Rico, Germany, United Kingdom, Austria
Janssen Scientific Affairs, LLC

Completed

A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform (DREaM)

Psychotic Disorders | Schizophrenia

United States, Brazil, Mexico
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Type 2 Diabetes Mellitus
Montefiore Medical Center

Completed

Comparative Efficacy of 4 Oral Analgesics

Pain

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study (SAMURAI)

Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Unresectable Renal Cell Carcinoma

United States
University of Utah

Enrolling by invitation

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

Ankle Fractures

United States
Baylor Research Institute

Completed

Safety Study Of Chemotherapy Combined With Dendritic Cell Vaccine to Treat Breast Cancer

Breast Cancer

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC
Pfizer

Completed

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Type 2 Diabetes Mellitus
Haukeland University Hospital

Completed

IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC (IMPACT)

Ovarian Cancer

Norway
Wake Forest University Health Sciences
Carolinas Trauma Network Research Group; Charlotte, Houston, Milwaukee Prehospital...

Completed

IN Sub-Dissociative Ketamine vs IN Fentanyl

Bone Fracture

United States
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Stanford University

Completed

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Breast - Female

United States
Seoul National University Hospital
Seoul National University Bundang Hospital; Korea University Guro Hospital; Gangnam... and other collaborators

Completed

Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain (CES_SNS_LBP)

Low Back Pain

Korea, Republic of
St. Jude Children's Research Hospital
Ohio State University; Arog Pharmaceuticals, Inc.

Completed

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Acute Myeloid Leukemia

United States
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and Pancreatic Cancer

Diabetes Mellitus, Type 2

Canada
Changhai Hospital

Recruiting

Endotherapy for Painless Chronic Pancreatitis (EACH)

Abdominal Pain | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency | Cholangiopancreatography, Endoscopic Retrograde

China
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach

Interaction Drug Food

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer

Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
Sanofi

Completed

Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive (ACADEMIC)

Type 2 Diabetes Mellitus

China
University of Utah

Active, not recruiting

Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures

Tibial Plateau Fractures

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Endothelial Hyperpolarization in Humans

Hyperlipidemia

United States
Tang-Du Hospital

Unknown

Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia

General Anesthesia

China
Rush University Medical Center

Terminated

Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL) (DLBCL)

Diffuse Large B-Cell Lymphoma

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)

Type 2 Diabetes Mellitus
Cerevel Therapeutics, LLC

Completed

A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants

Healthy Volunteers

United States
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and the Risk of Heart Failure

Type 2 Diabetes Mellitus

Canada
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and Acute Pancreatitis

Diabetes Mellitus, Type 2

Canada
Ain Shams University

Not yet recruiting

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Periapical Disease

Egypt
Celgene

Completed

A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

Heathy Volunteer

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

Type 2 Diabetes Mellitus

Search clinical trials for: Metformin ER

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